Diyabet-depresyon etkileşiminde kortizolün etkisi

Tüm dünyada diyabet hastalarının sayısı giderek artmaktadır. Çalışmalar diyabet hastalarında psikiyatrik bozuk-lukların normal populasyona göre daha sık olduğunu ve depresyonun bu hastalıkta normal populasyona göre iki kat fazla görüldüğünü göstermektedir. Diyabet sosyal sonuçları olan, kronik, uzun süreli komplikasyonları olan ve yeti yitimine yol açan bir hastalıktır ve bu durum depresyon gelişimi açısından önemlidir. Ancak ortaya çıkan hormonal değişimlerin bu sosyal etkiler dışında beyne olan etkileri de depresyon gelişimine katkıda bulunuyor ola-bilir. Bu gözden geçirme çalışmasında bazı yayınlarda diyabette ve depresyonda benzer şekilde arttığı gösterilen kortizol hormonunun beyne olan etkileri ve iki hastalık açısından karşılıklı etiyolojik önemi değerlendirilmiştir.

Anahtar Kelimeler:

Risk faktörleri, Depresyon, Diabetes mellitus, Hidrokortizon

The effects of cortisol in the interaction between diabetes and depression

The number of diabetes patients is increasing in all over the world. It is shown that psychiatric diseases are more common in diabetes patients than in normal population. Depression is also seen two folds in these patients when compared to normal population. Diabetes is a disease with social consequences, chronic complications and disabilities and these factors are important in depression occurrence. But apart from these social consequences, hormonal changes which occur with the disease process can also have some influences on development of depression. In this review, we evaluated the mutual etiological importance of cortisol hormone which was shown to increase similarly in both depression and diabetes in some of the articles and its effects on brain.

Keywords:

Risk Factors, Depression, Diabetes Mellitus, Hydrocortisone,

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