Ömer AKYÜREK, Erdem AKBAL, Fahri GÜNEŞ, Esra CAN SARIBACAK, Mustafa ALTINBAŞ

Hodgkin's Disease and Autoimmune Hemolytic Anemia: A Case Report

Hodking hastalığı lenfatik sistemin monoklonal malign bir hastalığıdır. Otoimmün hemolitik anemi, trombositopenive lökopeniler özellikle kronik lenfositik lösemi ve nonhodking lenfoma olmak üzre lenfoproliferatif hastalıklar ara- sında görülebilir, fakat bunlar hodking hastalığında nadiren görülür. En sık görülen hematolojik bulgu normokromiknormositik anemidir. Hodking hastalığında immün trombositopenik purpura, immün nötropeni gibi çeşitli immüno- lojik hastalıklar tanımlanmıştır. Bununla birlikte otoimmün hemolitik anemi, hodking hastalığında nadiren görülür.Biz bu yazıda direk coombs pozitif hemolitik anemi ve pansitopeniye neden olan hodking hastlıklı bir vaka sunduk.

Hodking Hastalığı ve Otoimmün Hemolitik Anemi: Vaka Sunumu

Hodgkin s disease is a distinct monoclonal malignant disorder of the lymphatic system. Autoimmune hemolyticanemia, trombocytopenia and leukopenia can be present with lymphoproliferative disease especially chronic lym- phocytic leukemia and Non-Hodgkin s lymphomas but they abnormalities rarely seen in Hodgkin s disease (1, 2).The most common hematologic finding is normocytic normochromic anemia. Various immunologic abnormalitiesincluding that immune thrombocytopenic purpura and immune neutropenia have been described in Hodgkin s dis- ease. However, autoimmune hemolytic anemia was rarely occurred in Hodking s Diseases. We reported a case whoHodgkin s disease lead to a direct coomb s positive hemolytic anemia and pancytopenia.

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