UYUZ HASTALIĞI (SKABİYES), TEDAVİSİ VE UYUZ HASTALIĞI TEDAVİSİNDE KULLANILAN BİTKİLER

Amaç: Uyuz hastalığı (Skabiyes) dünyada yaygın olarak görülen kaşıntılı, döküntülü ve bulaşıcı ektoparaziter bir hastalıktır. Etken Sarcoptes scabiei var. hominis adı verilen mikroskobik bir eklem bacaklıdır. Her yaş, cinsiyet, coğrafya ve kültürden insanı etkileyebilir. Gelişmekte olan ülkeler, tropikal ve subtropikal ülkelerde endemik olan parazit nedenli bu hastalık, büyük kalabalıklar ve hijyenin korunamadığı ortamlarda salgınlar yapabilir. Tedavide topikal ve oral olarak kullanılan seçenekler kısıtlı sayıdadır. Permetrin, Benzil Benzoat, Kükürtlü merhemler, Lindan, İvermektin gibi ilaçların birçoğu toksik etkilerinden dolayı bebek, çocuk, gebe ve laktasyon ile ilgili kısıtlılıklar nedeniyle risk altındaki tüm popülasyonlara uygulanamamaktadır. Scabiyes tedavi edilmediğinde, özellikle pediyatrik yaş grubunda görülen piyoderma, impetigo gibi sekonder enfeksiyonların da tabloya eklenmesi, hastalığın yükünü artırmaktadır. Bu nedenle daha az toksik etkileri olan ilaç arayışları halihazırda kullanılagelen bitkilere olan ilgiyi de canlı tutmaktadır.

SCABIES, SCABIES TREATMENT AND PLANTS USED IN THE TREATMENT OF SCABIES

Objective: Scabies are an itch and contagious ectoparasite that is common around the World. There is the causative Sarcoptes scabiei var. hominis. It can affect people of all ages, sexes, geographies and cultures. It is endemic in developing countries, tropical and subtropical countries. It can cause epidemics in large crowds and environments where hygiene cannot be maintained. Topical and oral options for treatment are limited. Drugs such as Permethrin, Benzyl Benzoate, Sulfur Ointments, Lindan, Ivermectin cannot be applied to all populations at risk due to their toxic effects, infants, children, pregnant women, and lactation-related restrictions. When scabies are not treated, the addition of secondary infections such as pyoderma and impetigo, which are seen especially in the pediatric age group, increases the burden of the disease. For that reason, the search for drugs with less toxic effects keeps the interest in plants still alive.

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Ankara Üniversitesi Eczacılık Fakültesi Dergisi-Cover
  • ISSN: 1015-3918
  • Yayın Aralığı: Yılda 3 Sayı
  • Başlangıç: 2016
  • Yayıncı: Ankara Üniversitesi Eczacılık Fakültesi
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