BAZI 1,2,4-TRİAZOL YOĞUNLAŞTIRILMIŞ TÜREVLERİNİN SENTEZİ, ÖZELLİKLERI VE BİYOLOJİK POTANSİYELİ

Amaç: Çalışmanın amacı 1,2,4-triazol, indol ve pirol içeren biyolojik olarak aktif heterosiklik sistemlerin sentezi için etkili yöntemler geliştirmektir. Bu çalısmada, öncelikle çalısma için gerekli olan on üç adet [1,2,4]triazolo[3,4-b][1,3,4]tiadiazol bilesigi sentezlenmistir.

Anahtar Kelimeler:

İndol, moleküler modelleme, pirol, sentez, 1-2-4-triazol

SYNTHESIS, PROPERTIES AND BIOLOGICAL POTENTIAL SOME CONDENSED DERIVATIVES 1,2,4-TRIAZOLE

Objective: The aim of the work was to develop effective methods for the synthesis of biologically active heterocyclic systems containing pyrrole, indole and 1,2,4-triazole. In this study, firstly fourteen [1,2,4]triazolo[3,4-b][1,3,4]thiadiazoles compounds requiring for this study were synthesized.

Keywords:

Docking, indole, pyrrole, synthesis, 1-2-4-triazole,

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