Kanser Hastalarında Kemoterapi Tedavisine Bağlı Gelişen Periferal Nöropatinin Yönetiminde Kanıta Dayalı Tamamlayıcı Yaklaşımlar

Kanser hastalarında kemoterapi ile ilişkili periferal nöropati hastanın günlük yaşam aktivitelerini ve yaşam kalitesini olumsuz etkileyen ve yaygın görülen semptomlardan biridir. Yapılan çalışmalarda periferal nöropatinin tedavi kesildikten sonraki ilk 1 yılda %67-80 oranında devam ettiği, bazı hastalarda ise %43 oranında kalıcı nöropati görüldüğü tespit edilmiştir. Kemoterapiye bağlı gelişen periferal nöropatinin yönetiminde sıklıkla ilaç dozunu azaltma, ilaca ara verme veya ilacı sonlandırma yapılmakta olup bu da hastaya uygulanan tedavinin etkinliğinin azalmasına neden olmaktadır. Periferal nöropatinin yönetimine farmakolojik ve akupunktur, refleksoloji, masaj, ayak banyosu, kriyoterapi, scrambler terapi, fiziksel aktivite gibi pek çok non-farmakolojik yaklaşım bulunmasına rağmen bu sorun güncelliğini korumakta ve yeni yöntemlerin etkinliği araştırılmaktadır. Bu derleme kemoterapiye bağlı periferal nöropatinin yönetiminde kullanılan, tamamlayıcı yaklaşımlara ilişkin çalışmaların gözden geçirilmesi amacıyla yazılmıştır

Evidence Based Complementary Approaches in the Management of Chemotherapy-Induced Peripheral Neuropathy in Cancer Patients

Peripheral neuropathy associated with chemotherapy in cancer patients is one of the common symptoms that adversely affects the patients’ daily life activities and life quality. In studies conducted, peripheral neuropathy was observed in 67–80% of patients in the first year after discontinuation of treatment, and 43% of patients had persistent neuropathy. Administration of chemotherapy-induced peripheral neuropathy often leads to a reduction in the dose of medication, intermittent discontinuation or drug termination, which reduces the efficacy of treatment administered to the patient. Although there are many pharmacological and non-pharmacologic approaches to manage peripheral neuropathy, such as acupuncture, reflexology, massage, foot bathing, cryotherapy, scrambler therapy, and other physical activities, this problem remains, and the effectiveness of new methods is being investigated. This review is written for the purpose of investigating the research on complementary approaches used in the management of chemotherapyinduced peripheral neuropathy.

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Koç Üniversitesi Hemşirelikte Eğitim ve Araştırma Dergisi-Cover

ISSN: 2618-5741
Yayın Aralığı: Yılda 4 Sayı
Başlangıç: 2004
Yayıncı: Koç Üniversitesi HYO Semahat Arsel Hemşirelik Eğitim ve Araştırma Merkezi (SANERC)