AYSEL GÜVEN, İNAN KAYA, HACİ AHMET DEVECİ, MİNE ERİŞİR, NADİDE NABİL KAMİLOĞLU, Alpaslan Kadir DEVRİM

Changes in liver and kidney arginase activities of geese after experimental tissue damage

Uzun süre karbon tetraklorür (CCk) ve etanol (C2H5OH) verilen kazlarda karaciğer ve böbrek arginaz aktiviteleri incelendi. CCU verilen gruptaki böbrek ve karaciğer arginaz aktiviteleri kontrol grubu ile karşılaştırıldığında önemli derecede düşük bulundu. Etanol verilen grupta ise böbrek arginaz aktivitesi önemli derecede yüksek bulunurken karaciğerde önemli derecede değişiklik gözlenmemiştir. Sonuçta, karaciğer ve böbrek hücrelerinin zarar gördüğü, arginaz aktivitesİnde de değişim olduğu ve bu değişimde böbreklerin karaciğere göre daha fazla etkilendiği görülmüştür.

Anahtar Kelimeler:

böbrekler, kümes hayvanları, zehirlenme, yan etkiler, arginaz, karbon tetraklorür, ilaç toksisitesi, enzim aktivitesi, etanol, kaz, karaciğer

Deneysel olarak doku dejenerasyonu oluşturulmuş kazlarda karaciğer ve böbrek arginaz aktivitesi değişimleri

The changes in arginase activity in the liver and kidney of geese were investigated through long-term treatment with carbon tetrachloride (CCU) and ethanol (C2H5OH). Compared to the control group, arginase activity in the kidneys and liver of the CCU treatment groups was found to be significantly decreased. Arginase activity in the kidney of the ethanol treated group was found to be significantly increased, whereas no significant differences were found in the hepatic arginase activity. These results show that arginase activity in the liver and kidney of geese is affected by cell damage. The kidney arginase is more sensitive than the liver arginase to cell damage.

Keywords:

kidneys, poultry, poisoning, adverse effects, arginase, carbon tetrachloride, drug toxicity, enzyme activity, ethanol, geese, liver,

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