Nuriza ZAMIRBEKOVA, Fatma ÇUHADAR ERDAL, Celal İZCİ

Sığırlarda tırnak lezyonlarında iyileşme ve tedavisinde temel yaklaşımlar

Süt sığırlarında ayak lezyonları etiyolojilerine göre enfeksiyöz ve non enfeksiyöz olarak sınıflandırılabilir. Non enfeksiyöz ayak lezyonları enfeksiyöz ayak lezyonlarından daha yaygın oluşur. En yaygın görülen non enfeksiyöz lezyonlar taban ülseri, taban ucu ülseri, taban hemorajisi ve beyaz çizgi hastalığıdır. Yara iyileşmesi genel olarak primer ve sekonder iyileşme olarak ikiye ayrılır. Tırnak lezyonları çoğunlukla primer iyileşme kriterlerine uymaz. Tırnağın hasar gördüğü ve koryumun açığa çıktığı tırnak lezyonlarında granülasyon dokusu oluşumu ile ikinci derecede bir iyileşme görülür. Sığırlarda tırnak lezyonlarını tedavi etmek için bilinen ve uygulanan birçok yöntem vardır. Bunların nasıl uygulanacağı, hangi hastalıkta hangisinin tek başına veya kombine olarak uygulanacağı, uygulama süreleri vb gibi konularda ciddi bir karmaşa vardır. Bilinçsiz ve doğru uygulanmadığında çoğu uygulamanın fayda yerine zarar verdiği saha gözlemlerimizle sabittir. Bu derlemenin amacı, süt sığırlarında sık görülen tırnak lezyonlarının iyileşmesi ve tedavisine yönelik güncel literatür bilgiyi özetlemek ve deneyimlere dayanarak sahadaki uygulayıcılara yol göstermektir.

Basic approaches to healing and treatment of claw lesions in cattle

Foot diseases can be classified as infectious and non-infectious according to their etiology. Non-infectious foot lesions occur more commonly than infectious ones. The most common non-infectious foot lesions are sole ulcer, toe ulcer, sole hemorrhage, and white line disease. Wound healing is generally considered as primary and secondary healing. There is often no primary improvement in claw lesions. In claw lesions where the nail and chorium are damaged, a secondary improvement is seen with the formation of granulation tissue. There is often no primary improvement in claw lesions. In these lesions where the claw and corium are damaged, a secondary improvement is observed with the formation of granulation tissue. There are many methods used in the treatment of claw lesions. It is important to know how to apply them in which disease. When not applied correctly, most applications harm instead of benefit. The purpose of this review is to summarize the current literature on the management of common claw horn lesions and to guide the practitioners in the field based on experience.

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Akköse M, İzci C, 2017. Süt ineklerinde yatma süresinin topallıklara etkisi ve yatma süresini etkileyen faktörler. Lalahan Hay Araşt Enst Derg, 57(1), 44-51.
Auer J, Stick J, 2012. Equine Surgery, Ed: Auer J, Stick J, 2nd ed., St Louis: Saunders Elsevier, Philadelphia, USA.
Azarabad H, Nowrouzian I, Soleymani E, Vakilgilani G, Seyedjavadi S, 2006. Wound healing process of uncomplicated “Rusterholz” ulcer following treatment by Wooden Block and Hoofgel in Bovine Hoof: histopathological aspects. Am J Anim Vet Sci, 1(2), 27–30.
Bicalho RC, Machado VS, Caixeta LS, 2009. Lameness in dairy cattle: a debilitating disease or a disease of debilitated cattle? A cross-sectional study of lameness prevalence and thickness of the digital cushion. J Dairy Sci, 92(7), 3175– 3184.
Blowey R, Weaver D, 2011. Color atlas of diseases and disorders of cattle, 3rd edition, Mosby Elsevier Ltd, London, UK.
Broughton IIG, Janis JE, Attinger CE, 2006. The basic science of wound healing, Plast Reconstr Surg, 117(7S), 12-34.
Calvin M, 1998. Cutaneous wound healing, Wounds, 10(1), 12-32.
Chapinal N, de Passille AM, Rushen J, Wagner S, 2010. Automated methods for detecting lameness and measuring analgesia in dairy cattle. J Dairy Sci, 93(5), 2007–2013.
Coetzee JF, Kleinhenz K, Pingsterhaus B, Schleining J, et al., 2014. Effect of topical treatment of claw horn lesions with tetracycline-derivatives on plasma and milk concentrations, In: 47th Annual Conference of the American Association of Bovine Practitioners, Albuquerque, NM, p. 137.
Coetzee JF, Shearer JK, Stock ML, Kleinhenz MD, et al., 2017.
An Update on the Assessment and Management of Pain Associated with Lameness in Cattle. Vet Clin Food Anim, 33(2), 389-411.
Cook NB 2003. Prevalence of lameness among dairy cattle in Wisconsin as a function of housing type and stall surface. J Am Vet Med Assoc, 223(9), 1324-1348.
Cook NB, Nordlund KV, 2009. The influence of the environment on dairy cow behavior, claw health and herd lameness dynamics. Vet J, 179(3), 360-369.
Edmondson MA, 2016. Local, regional, and spinal anesthesia in ruminants. Vet Clin Food Anim, 32(3), 535-552.
Flower FC, Sedlbauer M, Carter E, von Keyserlingk MAG, et al., 2008. Analgesics improve the gait of lame dairy cattle. J Dairy Sci, 91(8), 3010-3014.
Green LE, Huxley JN, Banks C, Green MJ, 2014. Temporal associations between low body condition, lameness and milk yield in a UK dairy herd. Prev Vet Med, 113(1), 63-71.
Greenough PR, 1987. Pododermatitis circumscripta (ulceration of the sole) in cattle. Agri Practic, 1, 17-22.
Gregory SS, 2007. The physiology of wound bed preparation, In: Surgical Wound Healing and Management, Ed: Granick MS, Gamelli RL, Informa, USA, pp; 1-16
Griffin D, Perino L, Hudson D, 1993. G93-1159 Feedlot Lameness. Erişim adresi: https://digitalcommons.unl.edu/ cgi/viewcontent.cgi?article=1195&context=extensionhist. Erişim tarihi: 16.07.2020.
Hernandez-Mendo O, von Keyserlingk MA, Veira DM, Weary DM, 2007. Effects of pasture on lameness in dairy cows. J Dairy Sci, 90(3), 1209-1214.
Hunt T, 2004. Wound Healing. Current Surgical Diagnosis & Treatment’de. Ed: Way LW, Doherty GM. United States of America: McGraw Hill, 75-88.
Hurley RW, Chatterjea D, Rose Feng M, Taylor CP, et al., 2002.
Gabapentin and pregabalin can interact synergistically with naproxen to produce antihyperalgesia. Anesthesiology, 97(5), 1263-1273.
Jones SG, Edwards R, Thomas DW, 2004. Inflammation and wound healing: the role of bacteria in the ımmuno-regulation of wound healing, Int J Low Extrem Wounds, 3(4), 201-208.
İzci C, 2001. “Sığırların Önemli Bir Ayak Hastalığı-LAMİNİTİS”. Tarım ve Köyişleri Bakanlığı, Koruma ve Kontrol Genel Müd., Hayvan Sağlığı Eğitim ve Yayın Serisi, Yayın no.8, ANKARA.
İzci C, 2013. Tırnak kesimi nasıl yapılır? Sığırlarda Topallık ve Ayak Hastalıkları Sempozyumu. 26-27 Nisan, Kervansaray Termal Otel, Bursa.
İzci C, Altan S, Gökşahin E 2013a. Bir inekte taban ucu ülseri. Sığırlarda Topallık ve Ayak Hastalıkları Sempozyumu. 26- 27 Nisan, Kervansaray Termal Otel, Bursa.
İzci C, Gökşahin E, Altan S, 2013b. Bir inekte abaksiyal beyaz çizgi hastalığı. Sığırlarda Topallık ve Ayak Hastalıkları Sempozyumu. 26-27 Nisan, Kervansaray Termal Otel, Bursa.
İzci C, Erol M, Çelik İ, et al., 2014. Boynuz Tırnak Lezyonu Bulunan Düve ve Süt İneklerinde Ökçe Yastığının Yapısal Özelliklerindeki Dönemsel Değişikliklerin Belirlenmesi. Tamamlanmış TÜBİTAK Projesi (1001), Proje No: 112O332
İzci C, Parlak K, Çuhadar F, 2016. Bir süt sığırında ökçe ülseri. 15. Ulusal 1. Uluslararası Veteriner Cerrahi Kongresi, 11- 14 Mayıs, Polat Erzurum Resort Hotel, Erzurum, 327.
İzci C, 2018. Sığırlarda Ayak Hastalıkları ve Topallık Kontrolü, Birinci Baskı, Selçuk Üniversitesi Basımev, Konya, Türkiye.
Kleinhenz K, Plummer P, Danielson J, Burzette RG, et al., 2014. Survey of veterinarians and hoof trimmers on methods applied to treat claw lesions in dairy cattle. Bovine Pract, 48, 47-52.
Klawitter M, Döpfer D, Braden T, et al., 2016. To bandage or not bandage - the curative effect of bandaging digital dermatitis lesions. Paper presented at: 29th World Buiatrics Congress. Dublin (Ireland), 174.
Kofler J, 1999. Clinical study of toe ulcer and necrosis of the apex of the distal phalanx in 53 cattle. Vet J, 157(2), 139- 147.
Kofler J, Glonegger-Reichert J, Dietrich J, Sykora S, et al., 2015. A simple surgical treatment for digital dermatitis-associated white line lesions and sole ulcers. Vet J, 204(2), 229- 231.
Leach KA, Logue DN, Kempson SA, Offer JE, et al., 1997. Claw lesions in dairy cattle: development of sole and white line haemor¬rhages during the first lactation. Vet J, 54(3), 215- 225.
Lischer CJ, Dietrich-Hunkeler A, Geyer H, Schulze J, et al., 2001. Healing process of uncomplicated sole ulcers in dairy cows kept in tie stalls: clinical description and blood chemical investigations. Schweiz Arch Tierheilkd, 143(3), 125-133.
Lischer CJ, Ossent P, Raber M, Geyer H, 2002. The suspensory structures and supporting tissues of the bovine 3rd phalanx and their relevance in the development of sole ulcers at the typical site. Vet Rec, 51(23), 694-698.
Manske T, Hultgren J, Bergsten C, 2002a. Prevalence and interrelationships of hoof lesions and lameness in Swedish dairy cows. Prev Vet Med, 54(3), 247-263.
Manske T, Hultgren J, Bergsten C, 2002b. The effect of claw trimming on the hoof health of Swedish dairy cattle. Prev Vet Med, 54(2), 113-129.
Mulling CKW, Lischer CJ, 2002. New aspects on etiology and pathogenesis of laminitis in cattle, In: Proc of the XXII World Buiatrics Congress (keynote lectures). Hanover, Germany, pp; 236-247.
Nagel D, Wieringa R, Ireland J, Olson ME, 2016. The use of meloxicam oral suspension to treat musculoskeletal lameness in cattle. Vet Medicine Research Rep, 7, 149-155.
Nguhiu-Mwangi J, Mbithi P, Wabacha J, Mbithi PMF, 2008.
Retrospective study of foot conditions in dairy cows in urban and periurban areas of Kenya. Isr J Vet Med, 63, 40-45.
Nuss K, 2016. Surgery of the distal limb. Vet Clin Food Anim, 32(3),753-775.
Offinger J, Herdtweck S, Rizk A, Starken A, et al., 2013. Postoperative analgesic efficacy of meloxicam in lame dairy cows undergoing resection of the distal interphalangeal joint. J Dairy Sci, 96(2), 866-876.
Ossent P, Lischer CJ, 1998. Bovine laminitis: the lesions and their pathogenesis. In Practice, 20(8), 415-427.
O’Toole EA, 2001. Extracellular matrix and keratinocyte migration. Clin Exp Dermatol, 26(6), 525-530.
Paetsch CD, 2014. Epidemiology of toe tip necrosis syndrome in Western Canadian feedlot cattle. Thesis Veterinary Medicine. Saskatoon (Canada): University of Saskatchewan.
Paetsch C, Fenton K, Perrett T, Janzen E, et al., 2017. Prospective case-control study of toe tip necrosis syndrome (TTNS)in western Canadian feedlot cattle. Can Vet J, 58(3), 247-254.
Pengov A, Flajs VC, Zadnik T, Marinšek J, et al., 2005. Distribution of chloramphenicol residues in lactating cows following an external application. Anal Chim Acta, 529(1–2), 347-351.
Pyman MF, 1997. Comparison of bandaging and elevation of the claw for the treatment of foot lameness in dairy cows. Aust Vet J, 7582, 132-135.
Raven T, 1989. Cattle footcare and claw trimming. Ipswich (United Kingdom): Farming Press.
Rigler DJ, 1997. Inflamation and repair. In: Veterinary Pathology, Ed: Jones TC, Hunt RD, King NW, 6nd Ed, Williams & Wilkins, Pennsylvania, ABD, pp; 150-157.
Rizk A, Herdtweck S, Offinger J, Meyer H, et al., 2012. The use of xylazine hydrochloride in an analgesic protocol for claw treat¬ment of lame dairy cows in lateral recumbency on a surgical tipping table. Vet J. 192(2), 193-198.
Schulz KL, Anderson DE, Coetzee JF, White BJ, et al., 2011.
Effect of flunixin meglumine on the amelioration of lameness in dairy steers with amphotericin B-induced transient synovitis-arthritis. Am J Vet Res, 72(11), 1431-1438.
Shaw G, 2017. Latest Lameness Research: A Summary. International Animal Health Journal, 4, 4, 36-9. Erişim adresi: www.animalhealthmedia.com Erişim tarihi: 10.10.2018.
Shearer JK, van Amstel SR, 2001. Functional and corrective claw trimming. Vet Clin North Am Food Anim Pract, 17(1), 53-72.
Shearer JK, Van Amstel SR, 2009. Toe lesions in dairy cattle. Paper presented at: 46th Florida Dairy Production Conference. Gainesville (FL), 28, 47-55.
Shearer JK, Van Amstel S, 2013. Manual of foot care in cattle, Ed: Atkinson F, 2nd edition, WI: WD Hoard and Sons Company, USA.
Shearer JK, Stock ML, Van Amstel SR, Coetzee JF, 2013. Assessment and management of pain associated with lameness in cattle. Vet Clin Food Anim, 29(1), 135-156. Shearer JK, Plummer PJ, Schleining JA, 2015a. Perspectives on the treatment of claw lesions in cattle. J Res Vet Med, 6, 273- 292.
Shearer JK, Plummer PJ, Schleining JA, et al., 2015b. Effect of topical treatment with oxytetracycline soluble powder or copper sulfate powder on healing of claw lesions. The 18th International Symposium and 10th International Conference on Lameness in Ruminants. Valdivia, Chile, 154.
Shearer JK, Van Amstel SR, 2017a. Traumatic Lesions of the Sole. Vet Clin Food Anim, 33(2), 271-281.
Shearer JK, Van Amstel SR, 2017b. Pathogenesis and Treatment of Sole Ulcers and White Line Disease. Vet Clin North Am Food Anim Pract, 33(2), 283-300.
Somers JG, Frankena K, Noordhuizen-Stassen KEN, Metz JHM.
2003. Prevalence of claw disorders in Dutch dairy cows exposed to several floor systems. J. Dairy Sci, 86, 2082-2093.
Stadelmann WK, Digenis AG, Tobin GR, 1998. Physiology and healing dynamics of chronic cutaneous wounds. Am J Surg, 176(2), 26-38.
Stashak TS, 1991. Principles of wound healing, In: Equine Wound Management, Ed:Lea& Febiger, Malvern, first edition, Pennsylvania, PA, pp; 1-15.
Stokka GL, Lechtenberg K, Edwards T, MacGregor S, et al., 2001. Lameness in feedlot cattle. Vet Clin North Am Food Anim Pract, 17(1), 189-207.
Tarleton JF, Holah DE, Evans KM, Jones S, et al., 2002. Biomechanical and histopathological changes in the support structures of bovine hooves around the time of first calving. Vet J, 163(2), 196-204.
Theoret CL, 2004. Update on wound repair, Clin. Tech. Equine Pract, 3(2), 110-122.
Van Amstel SR, Shearer JK, Palin FL, 2003. Case report – clinical response to treatment of pododermatitis circumscripta (ulceration of the sole) in dairy cows. Bovine Pract, 37, 143-150.
Van Amstel S, Shearer J, 2006. ‘Manual For Treatment and Control of Lameness in Cattle’. Blackwell Publishing, Ames, USA.
Van Amstel SR, Shearer JK, Cooper VL, 2011. Clinical presentation, treatment approach and histopathology of atypical digital dermatitis lesions. In: 16th Symposium and 8th Conference on Lameness in Ruminants, 2011, Rotorua, New Zealand.
Van Amstel SR and Shearer JK, 2011. Atypical digital dermatitis lesions. Proceedings of the International Symposium on Bovine Lameness. Rotorua (New Zealand).
Wang PH , Huang BS, Horng HC, Yeh CC, et al., 2018. Wound Healing. L Chin Med Assoc, 81(2), 94-101.
Whay HR, Webster AJ, Waterman-Pearson AE, 2005. Role of ketoprofen in the modulation of hyperalgesia associated with lameness in dairy cattle. Vet Rec, 157(23), 729-733.
Webster AJF 2002. Effects of housing practices on the development of foot lesions in dairy heifers in early lactation. Vet Rec, 151, 9-12.
White EM, Glickman LT, Embree C, 1981. A randomized field trial for evaluation of bandaging sole abscesses in cattle. J Am Vet Med Assoc, 178, 375-357.
Wilmink J, VanWeeren P, 2004. Treatment of exuberant granulation tissue. Clin Tech Equine Pract, 3(2), 141-147.