Successfull bleeding control with intermittent injection of factor VIII in a patient with hemophilia a during coronary artery bypass grafting surgery

Coronary surgery in patients with hemophilia is a challenging issue since it requires specific and a careful medical approach before, during and after the operation. Although several studies have shown the effectiveness of either intermittent or continuous infusion of factor VIII concentrates, there are no standardized schedules for the replacement therapy in these kinds of patients. We hereby present a case of severe hemophilia A and coronary event which was successfully managed by surgical approach supported by intermittent high dose factor VIII infusion. The patient underwent a surgical by-pass operation without any hemorrhagic and thrombotic complications..

Hemofili A Tanılı hastada koroner arter By-pass operasyonunda aralıklı faktör VIII uygulaması ile basarılı kanama kontrolü

Hemofili hastalarında koroner cerrahi, operasyon öncesi, operasyon sırası ve sonrasında özel ve dikkatli tıbbi yaklasım gerektirmektedir. Aralıklı veya sürekli faktör VIII infüzyonu uygulamalarının etkinlikleri açısından birkaç çalısma olmakla birlikte bu konuda net protokoller ortaya konabilmis değildir. Burada ağır hemofili A tanısı ve koroner hastalığı olan ve aralıklı yüksek doz faktör VIII infüzyonları ile basarılı bir operasyon geçiren bir hastayı sunmaktayız. By-pass operasyonu geçiren hastada kanama ve trombotik komplikasyon izlenmemistir..

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