Sesli Emel ÇETİN, Murat ÖZSAN, Arif ÖRSAL, İştar DOLAPÇI, Alper TEKELİ

Kemoterapi alan maligniteli hastalarda boğaz florasının değerlendirilmesi

Bu çalışmada Ankara üniversitesi Tıp Fakültesi İbn-i Sina Hastanesi Onkoloji Bilim Dal polikliniğinde takip edilen ve kemoterapi almakta olan 250 kanser hastasından alınan boğaz sürüntüsü örnekleri değerlendirildi. Yapılan değerlendirmede 10 hastada çeşitli gram negatif bakterilerin, 12 hastada Candida türlerinin, 6 hastada Staphyloccocus aureus'un, 1 hastada da beta hemolitik streptokokların floraya hakim hale gelmiş olduğu saptandı . Gram negatif bakteri hakimiyeti görülen 10 örneğin 6 sında E.coli, 1 inde Acinetobacter spp., 2 sinde Enterobacter spp. ve 1 inde Klebsiella spp. izole edildi. İkiyüzelli hastanın 29 unun (% 11.6) oral floralarında normalden sapma tespit edildi. Sonuç olarak bu hastaların oral floralarının yakın takip edilmesi ve kemoterapi öncesi ve sonrasında floranın değerlendirilerek olası infeksiyon durumlarında oral floranın da kaynak olarak akılda bulundurulması gerekmektedir.

Evaluation of oral microflora in patients with malignancy receiving chemotherapy

In this study we investigated the throat swab samples of 250 cancer patients receiving chemotherapy in the Oncology Department of Ankara University Medical Faculty Ibn-i Sina Hospital. The predominant organisms were gram negative bacteria in 10 patients, Candida spp. in 12 patients, Staphylococcus aureus in 6 patients and beta haemolytic streptococcus in 1 patient. Isolated gram negative bacteria were identified as E.coli (6 patients), Acinetobacter spp. (2 patients), Enterobacter spp. (2 patients) and Klebsiella spp. (1 patient). Changes in oral flora were detected in 29 patients (%11.6). Our results support the necessity to follow up the oral flora in this patient group and to keep in mind that oral flora may be the source of infection in many cases.

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