Preterm eylem yönetimi

Preterm Eylem Yönetimi Otuzyedinci gestasyonel haftadan önce olan doğumlar preterm eylem olarak isimlendirilir. Preterm eylem obs-tetrik mortalitenin ve morbiditenin en önemli nedenidir. Ekonomik ve emosyonel birçok etkisinin olması haricinde respiratuar, gastrointestinal, immünolojik, santral sinir sistemi, duyma ve görme problemleri gibi birçok fetal etkilere ve uzun dönem kognitif ve gelişimsel bozuk-luklara yol açmaktadır. Böyle ciddi sonuçları olan pre-term eylemin insidansı ilerleyen medikal gelişmelere rağmen günden güne artmaktadır. Preterm doğum için risk faktörleri arasında geçirilmiş preterm doğum öyküsü, erken membran rüptürü hikayesi, geçirilmiş servikal cerrahi, yardımcı üreme teknikleri (ART) ile gerçekleşmiş gebelik olması, uterin anomali, kısa servikal uzunluk, kronik uriner traktus infeksiyonu, maternal Body Mass Index (BMI)’ın düşük olması gibi birçok neden suçlan-maktadır. Yapılan birçok araştırma olmasına rağmen halen preterm eylemin önlenmesinde ve yönetiminde kesin kurallar bulunmamaktadır. Gestasyonel haftaya göre kortikosteroid, tokoliz ve antibiyotik tedavileri multidisipliner bir çerçevede uygu-lanmalıdır ancak şüphesiz ciddi komplikasyonlara yol açan preterm eylemi öngörebilmek ve önleyebilmek esas hedef olmalıdır.

Management of preterm labour

Preterm labour is that born at less than 37 completed weeks of gestation which is the most important cause of the obstetric mortality and morbidity. The birth of a preterm infant brings emotional and economic costs to families and also respiratory, gastrointestinal, immu-nologic, central nervous system, hearing, and vision problems, as well as longer term motor, cognitive, visual, hearing, and growth problems. Despitethese gross results the incidance of preterm labour has increased steadily. Previous preterm labour, preterm premature rupture of membranes (PPROM), previous servical surgery, pregnancy with asiste reproductive technology (ART), uterine abnormality, short servical lenght, cronic urinary tractus infection and less maternal BMI are the risk factors for preterm labour. In contravention of many studies there is no consensus for prevention or treatment of preterm labour. According to week of gestation treatment options are corticosteroids, tocolitic theraphies and antibiotics in a multidisipliner way. But surely the principle aim must be prediction and prevention of preterm labour.

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  • 1. Ananth CV, Vintzileos AM. Epidemiology of preterm birth and its clinical subtypes. J Matern Fetal Neonatal Med 2006;19: 773-82.
  • 2. Meis PJ, Goldenberg RL, Mercer BM, Iams JD, Moawad AH, Miodovnik M, et al. The Preterm Prediction Study: Risk factors for indicated preterm births. Maternal-Fetal Medicine Units Network of the National Institute of Child Health and Human Development. Am J Obstet Gynecol 1998;178: 562–67.
  • 3. March of Dimes Web site. Born too soon and too small in the United States. March of Dimes Birth Defects Foundation PeriStats. Updated May, 2006. Available from: www:marchofdimes.com/peristats [Accessed August 5, 2006].
  • 4. Martin JA, Hamilton BE, Sutton PD, Ventura SJ, Menacker F, Kirmeyer S. Births: Final data for 2004: National Vital Statistics Report (vol 55, no 2), National Center for Health Statistics, Hyattsville, MD (2006).
  • 5. Bittar RE, Yamasaki AA, Sasaki S, Zugaib M. Cervical fetal fibronectin in patients at increased risk for preterm delivery. Am J Obstet Gynecol 1996;175: 178-81.
  • 6. Crowley PA. Antenatal corticosteroid therapy: a metaanalysisof the randomized trials, 1972 to 1994. Am J Obstet Gynecol 1995;173: 322-35.
  • 7. Engle WA. A recommendation for the definition of “late preterm” (near-term) and the birth weight-gestational age classification system. Semin Perinatol 2006;30: 2–7.
  • 8. Reedy NJ. Born too soon: the continuing challenge of preterm labor and birth in the United States. J Midwifery Womens Health2007;52: 281-90.
  • 9. Hoffman HJ, Bakketeig LS. Risk factors associated with the occurrence of preterm birth. Clin Obstet Gynecol 1984;27: 539–42.
  • 10. Hoffman HJ, Bakketeig LS. Epidemiology of preterm birth: Results from a longitudinal study of births in Norway. In: MG Elder and CH Hendricks 1981;93–115.
  • 11. Iams JD. Prediction and early detection of preterm labor. Obstet Gynecol 2003;101: 402-12.
  • 12. Talmud PJ, Humphries SE. Gene: environment interactions and coronary heart disease risk. World Rev Nutr Diet 2004;93: 29-40.
  • 13. Mattison DR, Damus K, Fiore E, Petrini J,Alter C. Preterm delivery: a public health perspective. Paediatr Perinat Epidemiol 2001; 7-16.
  • 14. Berghella V, Odibo AO, To MS, Rust OA, Althuisius SM. Cerclage for short cervix on ultrasonography: meta-analysis of trials using individual patient-level data. Obstet Gynecol2005;106: 181-9.
  • 15. Chao AS, Chao A, Hsieh PC. Ultrasound assessment of cervical length in pregnancy. Taiwan J Obstet Gynecol2008;47: 291-5.
  • 16. Behrman RE, Butler AS. Preterm Birth: Causes, Consequences, and Prevention: National Academies Press (US); 2007.
  • 17. Errol R, Norwitz N, Julian N, Robinson. A Systematic Approach to the management of Preterm Labor. Seminars in perinatology 2001;25: 223-5.
  • 18. Canavan, Timothy P, FACOG Simhan, Hyagriv N, MSCR; Caritis, Steve MD. An Evidence-Based Approach to the Evaluation and Treatment of Premature Rupture of Membranes. Obstetrical & Gynecological Survey: 2004;59: 678-89.
  • 19. Tan TC, Devendra K, Tan LK, Tan HK. Tocolytic treatment for the management of preterm labour: a systematic review. Signapore Med J2006;47:361-6
  • 20. Management of Preterm Labour. ACOG Practice Bulletin No 43, May 2003.
  • 21. King JF, Flenady VJ, Papatsonis DN, Dekker GA, Carbonne B. Calcium channel blockers for inhibiting preterm labour. Cochrane Database Syst Rev 2002;2: CD002255.
  • 22. Anyaegbunam WI, Adetona AB. Use of antenatal corticosteroids for fetal maturation in preterm infants. Am Fam Physician 1997;56: 1093- 6.
  • 23. Crowley P. Prophylactic corticosteroids for preterm birth. Cochrane Database Syst Rev 2007;3: CD000065.
  • 24. Smith GN. What are the realistic expectations of tocolytics? BJOG 2003; 110: 103-6.
  • 25. Bozdağ H, Ertekin K, Sezer H. Erken membran rüptürü ve erken doğum eylemi olgularında serum ferritin düzeyi. Zeynep Kamil Tıp Bulteni. 2003;34: 13-6.
  • 26. Greenfield PJ, Lamont RF. The contemporary use of tocolytics. Current Obstet Gynaecol 2000;10: 218-24.
  • 27. Toprak E, Yardımcı OD, Tapısız Ö, Aytan H, Özel M, Tonguç E, ve ark. Erken doğum eylemine profilaktik yaklaşımda oral magnezyum tedavisinin rolü. Türkiye Klinikleri Jinekol Obs 2003: 13-5.
  • 28. Lyell DJ, Pullen KM, Mannan J, Chitkara U, Druzin ML, Caughey AB, et al. Maintenance nifedipine tocolysis compared with placebo: a randomized controlled trial. Obstet Gynecol 2008;112: 1221-6. 29. Lyndrup J, Lamont RF. The choice of a tocolytic for the treatment of preterm labor: a critical evaluation of nifedipine versus atosiban. Expert Opin Investig Drugs 2007;16: 843-53.
  • 30. Papatsonis D, Flenady V, Cole S, Liley H.Oxytocin receptor antagonists for inhibiting preterm labour. Cochrane Database Syst Rev 2005;20: CD004452. 31. Mercer BM, Lewis R.Preterm labor and preterm premature rupture of the membranes. Diagnosis and management. Infect Dis Clin North Am1997;11: 177-201.
  • 32. Reimer T, Ulfig N, Friese K. Antibiotics: treatment of preterm labor. J Perinat Med1999;27: 35-40.
Yeni Tıp Dergisi-Cover
  • ISSN: 1300-2317
  • Yayın Aralığı: Yılda 4 Sayı
  • Başlangıç: 2018
  • Yayıncı: -
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