Koçlarda Aflatoksinin Böbrek Üzerine Etkileri ve Esterifiye Glukomannanın Koruyucu Etkinliği

Bu çalışmada Merinos ırkı koçlara ağızdan verilen total aflatoksinin (AF) böbrek üzerine etkileri ile glukomannanın (EG) koruyucu etkinliği değerlendirildi. Çalışmada 1 yaşında 32 adet koç 4 eşit gruba ayrıldı. Beslemeye 92 gün devam edildi. Kontrol (K) grubuna ticari yem; AF grubuna ticari yem ile günlük 250 µg AF; EG grubuna ticari yem ile günlük 2 gr EG; AF+EG grubuna ise ticari yemle birlikte günlük 250 µg AF ve 2 gr EG verildi. 92. günün sonunda hayvanlar kesildikten sonra böbrekteki histolojik yapıyı göstermek için örnekler alındı. AF grubunun böbrek tübüllerinde dejenerasyon ve dökülmeler, böbrek damarlarında ise yoğun hiperemi gözlendi. Sonuç olarak; aflatoksikozun böbrek üzerindeki olumsuz etkilerinin yeme EG ilave edilerek iyileştirilebildiği ortaya konmuştur.

Effects of Aflatoxin on Kidney and Protective Effectiveness of Esterified Glucomannan in Ram

In this study, the effects of total aflatoxin (AF) given orally on kidney in Merino rams were studied. In addition, this study was conducted in order to evaluate the efficacy of an esterified glucomannan (EG) for protection against to aflatoxicosis. One year-old 32 Merino rams were divided into four equal groups. Rams were fed through the 92 days. Control group (C) fed with the commercial feed. AF group fed with commercial feed added 250 µg/day of total AF. EG group fed with commercial feed added 2 g/day of EG. AF+EG group fed with commercial feed added 250 µg/day of total AF and 2 g/day of EG. At the end of the 92 day after cessation of the animals, tissue samples were taken from the kidney in order to perform histological structure. Degeneration and spills in the tubular epithelial cells of kidney were observed in the AF group. Massive hyperemia was observed in the renal vessels. In conclusion, the adverse effects causing by aflatoxicosis on the kidney could be ameliorated by adding EG to the ration.

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Van Veterinary Journal-Cover
  • ISSN: 2149-3359
  • Başlangıç: 1990
  • Yayıncı: Yüzüncü Yıl Üniv. Veteriner Fak.