Karma yemlere katılan narasin ve nikarbazinin, zeolit ile etkileşiminin etlik piliçlerin ince bağırsak ağırlığı, tibial diskondroplazi, tibia külü ve kan parametreleri üzerine etkileri

Bu çalışmanın amacı, karma yemlere katılan narasin ve nikarbazinin, zeolit ile etkileşiminin, etlik piliçlerin ince bağırsak ağırlığı (g/100 g canlı ağırlık), iç organ ağırlıkları (karaciğer, taşlık, kalp - g/100 g canlı ağırlık), kan serumu sodyum (Na), potasyum (K), klor (CI) konsantrasyonları, altlık rutubeti, kemik külü ve tibial diskondroplazi (TD) üzerine etkilerinin belirlenmesidir. Denemede toplam 3 12 adet bir günlük yaşta Avian Farms broyler erkek civciv kullanılmış ve civcivler 4 ana gruba ayrılmıştır. Ayrıca her ana grup, her biri 13 adet civciv içeren 6 tekrar grubuna ayrılmıştır. Deneme süresince Grup NA, Grup NAZ, Grup Nİ ve Grup NlZ'in izokalorik ve izonitrojenik yemlerine sırasıyla, 70 mg/kg narasin, 70 mg/kg narasin + % 2 zeolit, 125 mg/kg nikarbazin, 125 mg/kg nikarbazin + % 2 zeolit katılmıştır. Denemenin 21. gününde NAZ grubunun ince bağırsak ağırlığı, Nİ ve NİZ grubundan önemli düzeyde düşük bulunmuştur (P

Anahtar Kelimeler:

diskondroplazi, kan parametreleri, zeolit, tibia, narasin, etlik piliç, karma yemler, bağırsaklar, nikarbazin, kemik külü

The effect of interaction between narasin and nicarbazin with zeolite supplemented to mixed feed on small intestine weight and tibial dyschondroplasia, tibia ash and blood parameters of broiler chickens

The aim of this study was to determine the effects of interaction between narasin and nicarbazin with zeolite supplemented to the feeds on small intestine weight (g/100 g body weight), organ weights (liver, gizzard, heart- g/100 g body weight), blood serum sodium (Na), potassium (K), chlorine (Cl) concentrations, litter moisture, bone ash and tibial dyschondroplasia (TD) of broiler chickens.In the experiment, a total of 312 one day old male broiler chicks (Avian Farms) were used and divided into main four groups. Also, each group was divided again into 6 replicate groups each containing 13 chicks. During the experiment, isocaloric and isonitrogenic feeds of Group NA, Group NAZ, Group Nİ and Group NİZ were supplemented with 70 mg/kg narasin, 70 mg/kg narasin + 2 % zeolite, 125 mg/kg nicarbazin, 125 mg/kg nicarbazin + 2 % zeolite, respectively. For the first 21 days, small intestine weight of NAZ group was found significantly less (PO.01) than Nİ and NİZ groups. In the same period, blood serum Cl concentration of NA group was higher than Nİ and NİZ groups (PO.001). Also, blood serum Cl concentration of NİZ was found significantly less than NAZ group (PO.001). Moreover, at 40 days of the experiment we have observed that the level of blood serum Na concentration in N A group was significantly lower than both of Nİ and NİZ groups (PO.001), as for the level of K concentration was lower only in Nİ containing group (PO.05). Zeolit supplementation (2 %) to the feeds of NAZ and NİZ groups resulted in a reduction of incidence and severity of tibial dyschondroplasia, compared with N A and Nİ groups at 21 days of age. Litter moisture of N A and Nİ groups were determined significantly higher than NAZ group at the end of the trial (PO.001). No significant différents were noted between other parameters. As a result, zeolite supplementation to the broiler feeds which contain narasin and nicarbazin decrased the incidence of tibial dyschondroplasia at 21 days old, and also, utilisation of narasin with zeolite reduced small intestine weight and decreased litter moisture. These results suggested that combined use of narasin and nicarbazin with zeolit in feeds might have beneficial influence on broilers.

Keywords:

dyschondroplasia, blood parameters, zeolites, tibia, narasin, broilers, compound feeds, intestines, nicarbazin, bone ash,

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1. A.O.A.C.: Official Methods of Analysis (9th Ed.) Vail-Balloa Pres Inc., Binghampton, N.Y., 38: 1165, 1980.

2. A.O.A.C.: Official Methods of Analysis, Vail- Balloa Pres Inc., Binghampton, N.Y., 38: 10-11, 1996.

3. ALTAN, A., ALTAN, Ö., ALÇİÇEK, A., NALBANT, M., AKBAŞ, Y.: Tavukçulukta Doğal Zeolit Kullanımı: I.Altlığa Zeolit İlavesinin Etlik Piliç Performansı, Altlık Nemi ve Amonyak Kon santrasyonu Üzerine Etkileri. Ege Üniv. Zir. Fak. Derg. 35 (1-2-3), 1998.

4. ALTINTAŞ, A., FİDANCI, U.R.: Evcil Hayvan larda ve İnsanda Kanın Biyokimyasal Normal De ğerleri. Ankara Üniv. Vet. Fak. Derg. 40: 173-186, 1993.

5. ARMSTRONG, D.G.: Antibiotics as Feed Additives for Ruminant. WOUDLINE M, eds. Antimicrobials and Agriculture. Butterworth, Chapter 27, London, 331-348, 1984.

6. BAILEY, R.H., KUBENA, L.F., HARVEY, R.B., BUCKLEY, S.A., ROTTINGHAUS, G.E.: Efficacy of Various Inorganic Sorbents to Reduce the Toxicity of Aflatoxin and T-2 Toxin in Broiler Chickens. Poultry Sci. 77: 1623-1630,1998.

7. BALLARD, R., EDWARDS, H.M.: Effects of Dietary Zeolite and Vitamin A on of Tibial Dyschondroplasia in Chickens. Poultry Sci. 67: 113-119, 1998.

8. ÇOLPAN, İ., YALÇIN, S., ERGÜN, A., TUNCER, Ş.D., KÜÇÜKERSAN, K., ÜNAL, A., YILDIZ, G.: Zeolitin Hayvan Beslemede Kulla nılması Üzerine Çalışmalar. Marmara Bölgesi II. Hayvancılık Kongresi, Uludağ Üniversitesi Veteri ner Fakültesi, Kirazlıyayla, Bursa, 1995.

9. EDWARDS, H.M. Observations on Several Factors Influencing The Incidence of Tibial Dyschondroplasia in Broiler Chickens. Poultry Sci. 64: 2325-2334, 1985.

10. EDWARDS, H.M.: Efficacy of Several Vitamin D Compounds in The Prevention of Tibial Dyschondroplasia in Broiler Chicks. Americ. Inst. of Nutr. 4:1054-1061, 1990.

11. EDWARDS, H.M., VELTMANN, J.R.: The Role of Calcium and Phosphorus in the Etiology of Tibial Dyschondroplasia in Young Chicks. J. Nutr. 113: 1568-1575, 1983.

12. ELLIOT, A.M., EDWARDS, H.M.: Comparison of the Effects of Synthetic and Natural Zeolite on Laying Hen and Broiler Chicken Performance. Poultry Sci. 70: 2115-2130, 1991.

13. EYSSEN, H., SOMER, P.: Effect of Antibiotics on Growth and Nutrient Absorption of Chicks. Poultry Sci. 42: 1373-1379, 1963.

14. FETHIERE, R., MILES, D.R.: Intestinal Tract Weight of Chicks Fed an Antibiotic and Probiotic. Nutr. Rep. Int. 36: 1305-1309, 1987.

15. HARTEL, H.: Relations Between N-Corrected Metabolisable Energy and Nutrient Content of Feeds for Chickens. Archiv Fuer Gefluegelkunde, 41: 152-182, 1977.

16. HOOGE, D.M.: Dietary Electrolytes Influence Metabolic Processes of Poultry. Feedstuffs, 12: 14- 21, 1995.

17. JOHNSON, R.J., KARUNAJEEWA, H.: The Effects of Dietary Minerals and Electrolytes on Growth and Physiology of The Young Chick. J. Nutr. 115: 1680-1690, 1985.

18. KARUNAJEEWA, H., BARR, D.A.: Influence of Dietary Electrolite Balance, Source of Added Potassium and Anticoccidial Agents on the Performance of Male Broilers. British Poultry Sci. 29:137-147, 1988.

19. KAYA, S., PİRİNÇÇİ, İ., TRAŞ, B., BİLGİLİ, A., BAYDAN, E., AKAR, F., DOĞAN, A.: Veteriner Uygulamalı Farmakoloji, Ed. KAYA, S., PİRİNÇÇİ, İ.: Protozoonları Etkileyen İlaçlar. Yay.: 2, Medisan Yayın Serisi, Ankara, 457, 1997.

20. KUBENA, L.F., HARVEY, R.B., BAILEY, R.H., BUCKLEY, S.A., ROTTINGHAUS, G.E.: Effects of a Hydrated Sodium Calcium Aluminosilicate (T- Bind) on Mycotoxicosis in Young Broiler Chickens. Poultry Sci. 77: 1502-1509, 1998.

21. LEACH, R.M., NESHEIM, M.C.: Nutritional, Genetic and Morphological Studies of an Abnormal Cartilage Formation in Young Chicks. J. Nutr. 86: 236-244, 1965.

22. LEDOUX, D.R., ROTTINGHAUS, G.E., BERMUDEZ, A.J., ALONSO-DEBOLT, M.: Efficacy of a Hydrated Sodium Calcium Aluminosilicate to Ameliorate the Toxic Effects of Aflatoxin in Broiler Chicks. Poultry Sci., 78:204- 210, 1999.

23. MONGIN, P.: Recent Advances in Dietary Anion Cation Balance in Poultry. COLE, D.J.A., HARESIGN, W. eds. Recent Developments in Poultry Nutrition, Anchor Press Ltd, Essex, UK. 94-104, 1989.

24. MUMPTON, F.A., FISHMAN, P.H.: The Application of Natural Zeolites in Animal Science and Aquaculture. J. Anim. Sci. 45: 1188-1203, 1977.

25. OLVER, M.D.: Effect of Feeding Clinoptilolite (Zeolite) to the Tree Strains of Laying Hens. British Poultry Sci. 30:115-121, 1989.

26. OYAWOYE, E.O., KRUEGER, W.F.: The Potential of Monensin For Body Weight Control and Ad Libitum Feeding of Broiler Breeders from Day- Old to Sexual Maturity. Poultry Sci. 65: 884- 891, 1986.

27. PRAUL, C.A., FORD, B.C., GAY, C.V., PINES, M., LEACH, R.M.: Gene Expression and Tibial Dyschondroplasia. Poultry Sci. 79: 1009-1013, 2000.

28. RABON, H.W., ROLAND, D.A., BRYANT, M.M.: Absorption of Silicon and Aluminium by Hens Fed Sodium Zeolite A with Various Levels of Dietary Cholecalciferol. Poultry Sci. 74: 352-359, 1995.

29. RAND, M.C., GREENBERG, A.E., TARAS, M.J., FRANSON, M.A.: Standard Methods For the Examination of Water and Waste Water, 14 th Edition, APHA-AWWA-WPCF, 234-235, 1975.

30. RAND, M.C., GREENBERG, A.E., TARAS, M.J., FRANSON, M.A.: Standard Methods For the Examination of Water and Waste Water, 14 th Edition, APHA-AWWA-WPCF, 250-253, 1975.

31. SORRIBAS, V., ARRUEBO, M.P., NAVARRO, H., ALCALDE, A.I.: Nicarbazin Stimulates Intestinal Transport of L - Leucine in Rabbit. Journal of Vet. Pharm. Therapeutics. 16: 32-7, 1993.

32. Suda Çözünebilir Klorür Tayini, Resmi Gazete, Sayı: 19034, 9-10, 1986.

33. SÜMBÜLLÜOĞLU, K.: Bioistatistik, 6. Baskı, Özdemir Yayıncılık, Ankara, 1995.

34. SWEENNEY, D.J., KENNINGTON, A., DONOHO, A.L.: Tissue Residues and Metabolism of Narasin in Chicken. Journal of Agricaltural Food Chemistry, 44: 2829- 2834, 1996.

35. ŞENEL, H.S.: Interrelationship and Effects of Calcium and Vitamin D on Growth, Feed Efficiency and Bone Ash Weanlingrats. Ankara Üniv. Vet. Fak. Dergisi, Ankara Üniv. Basımevi, 15:1, 1968.

36. ŞENGÜLER, İ., YILMAZ, H.: Depolama Alanla rında Oluşan Gazın Çevresel Etkileri ve Ekonomik Potansiyeli. Jeoloji Mühendislik Dergisi, 44-66, 1994.

37. T.C. MADEN TETKİK ARAMA GENEL MD. MADEN ANALİZLERİ VE TEKNOLOJİSİ DAİRESİ BAŞKANLIĞI: Zeolit Madeninin Minerolojik, Kimyasal, Fiziksel Özellikleri, Ek.2.MAT Dai. BŞK’.nın 5.12.1994 tarih ve 1174 sayılı raporu, Ankara, 1994.

38. TANRIVERMİŞ, H., GÜNDOĞMUŞ, E.: Türkiye Tavukçuluğunda Dikey Entegrasyon Eğilimleri. YUTAV 99, Uluslararası Tavukçuluk Fuarı ve Konferansı, İstanbul, Türkiye, 564-565, 1999.

39. VALTEC.: Reagent Set For Quantitative Determination of Chloride in Serum and Plasma. Valdes Compania Limitada, Las Dalias 1900, Nunoa, Santiago-Chile.

40. VISEK, W.J.: The Mode of Growth Promotion by Antibiotics. Journal of Animal Sci. 46: 1447-1469, 1978.

41. WARD, T.L., WATKINS, K.L., SOUTHERN, L.L.: Interactive Effects of Sodium Zeolite A (Ethacal) and Monensin in Uninfected and Eimeria Acervulina - Infected Chicks, Poultry Sci., 69: 276- 280, 1990.