Bazı Esansiyel Yağların Metisiline Dirençli Staphylococcus aureus ÜzerineEtkileri

Gıda ve tıp alanlarında mikrobiyal kontaminasyon insan sağlığını yakından ilgilendiren bir durumdur. Kontaminasyona neden olan mikroorganizmaların yüksek antibiyotik direncine sahip olması kontaminasyonun ortadan kaldırılmasını güçleştirmektedir. Hatalı antibiyotik kullanımı veya yeni antibiyotiklerin bulunmaması gibi durumlar mikroorganizmaların çoklu antibiyotik direnci kazanmasına neden olmuştur. Yüksek antibiyotik direncine sahip mikroorganizmaların başında metisiline dirençli S. aureus (MRSA) gelmektedir. MRSA’nın sahip olduğu antibiyotik direnç mekanizmaları ve biyofilm üretim kabiliyeti kendisini çevreye karşı daha dirençli hale getirmiştir. Bu çalışmada Heracleum platytaenium ve Lavandula spp. esansiyel yağlarının MRSA’ya karşı antimikrobiyal aktivitelerinin belirlenmesinde disk difüzyon yöntemi kullanılmış olup sonuçlar ticari antibiyotikler ile kıyaslanmıştır. Ayrıca H. platytaenium ve Lavandula spp. esansiyel yağının MRSA tarafından üretilen biyofilm üzerine etkisi de araştırılmıştır. Bu çalışmada, H. platytaenium ve Lavandula spp. esansiyel yağlarının MRSA’ya karşı bir antimikrobiyal akvitiye sahip olduğunu ortaya koymuştur. H. platytaenium ve Lavandula spp. esansiyel yağlarının antibiyofilm aktiviteye sahip olduğu belirlenmiştir. MRSA kaynaklı kontaminasyonların kontrol edilmesinde ticari antibiyotiklere kıyasla H. platytaenium ve Lavandula spp. esansiyel yağlarının alternatif doğal kaynaklar olabileceği bulunmuştur.

The Effects of Some Essential Oils on Methicilin Resistant Staphylococcus aureus

Microbial contamination in food and medicine is a situation that closely concerns human health. The fact that the microorganism causing the contamination have antibiotic resistance makes it difficult to eliminate the contamination. Deficiencies such as incorrect use of antibiotics or lack of new antibiotics have caused microorganisms to acquire multiple antibiotic resistance. Methicillin-resistant S. aureus (MRSA) is one of the microorganisms with high antibiotic resistance. The antibiotic resistance mechanisms and biofilm production ability of MRSA has made it more resistant to the environment. In this study, disc diffusion method was used to determine the antimicrobial activities of Heracleum platytaenium and Lavandula spp. essential oils against MRSA, and the results were compared with commercial antibiotics. In addition, the effect of H. platytaenium and Lavandula spp. essential oils on the biofilm produced by MRSA was also investigated. In this study, it was determined that H. platytaenium and Lavandula spp. essential oils have antimicrobial activity against MRSA. It was found that H. platytaenium and Lavandula spp. essential oils have antibiofilm activity against MRSA. H. platytaenium and Lavandula spp essential oils can be alternative natural sources compared to commercial antibiotics in controlling infections from MRSA.

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