Asuman BİRİNCİ, Tekin AKPOLAT, Şahin ÖZDEMİR, Belma DURUPINAR

Hemodiyaliz hastalarında staphylococcus aureus burun taşıyıcılığı ve izole edilen suşların antibiyotik duyarlılığı

Burunda Staphylococcus aureus taşıyıcılık oranı kronik dermatitlilerde, allerjik rinitlilerde, insulin kullanan diabetiklerde ve hemodiyaliz hastalarında normal popülasyondan daha yüksektir. Hemodiyaliz hastalarında bakteriyemi ataklarında kandan en sık izole edilen mikroorganizmanın S.aureus olması infeksiyonun patogenezinde S.aureus burun kolonizasyonunun rolünü düşündürmektedir. Çalışmada hemodiyaliz hastalarında S.aureus burun taşıyıcılığı ve izole edilen suşların antibiyotik duyarlılığı araştırılmıştır. Araştırılan 59 hemodiyaliz hastasının 36 (%61)'sının burun kültüründe S.aureus saptanmıştır. İzole edilen S.aureus suşlarının antibiyotik direnci ise; metisiline %16.7, penisiline %97.5, tetrasikline %55.6 olarak belirlenmiş, vankomisin ve teikoplanin direncine rastlanmamış; çalışılan diğer antibi-yotiklere (ampisilin-sulbaktam, gentamisin, sefalotin, sefoksitin, sefuroksim, sefepim, siprofloksasin, eritromisin, trimetopim-sulfametaksazol.klindamisin, imipenem) ise %2.8-55.6 arasında değişen direnç saptanmıştır.

Nasal carriage and antibiotic susceptibilities of staphylococcus aureus strains isolated from haemodialysis patients

Nasal carriage rate of Staphylococcus aureus is higher in patients with chronic dermatitis, allergic rhinitis, insulin dependent diabetics and also in haemodialysis patients than the normal population . The most common microorganism isolated from blood during the bacteriemic episodes of haemodialysis patients is S.aureus, so it is thought that nasal carriage of S.aureus has a role in etiopathogenesis of infection,In this study nasal carriage and antiobiotic susceptibility of S.aureus isolates were investigated. S.aureus strains were isolated from 36 (61%) nasal cultures of 59 haemodialysis patients.The antibiotic resistance of S.aureus isolates was found 16.7% to penicillin and 55.6% to tetracyclin; no resistance was detected to vancomycin or teicoplanin; the resistance rates were between 2.8% and 55.6% for the other antibiotics (ampicilin-sulbactam, gentamicin, cefalotin, cefoxitin, cefuroxim, cefepim, ciprofloxacin, eritromicin, trimetopim-sulfametaxazol,clindamicin, imipenem) tested in this study.

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