Evre I akciğer adenokarsinomu için prognostik faktörler ve subsolid nodüllerin cerrahi yönetimi

Amaç: Bu çalışmada evre I akciğer adenokarsinomu için prognostik faktörler tespit edildi ve subsolid nodüllerin cerrahi yönetimi değerlendirildi. Çalışma planı: Çalışmaya kliniğimizde Ocak 2007 - Aralık 2015 tarihleri arasında evre I akciğer adenokarsinomu nedeniyle ameliyat edilen 133 hasta (90 erkek, 43 kadın; ort. yaş 64.9 yıl; dağılım, 29-82 yıl) dahil edildi. Klinik, radyolojik ve patolojik veriler geriye dönük olarak değerlendirildi ve bunların nüks ve sağkalım üzerindeki etkileri Kaplan-Meier ve Cox regresyon analizleri ile incelendi. Bulgular: Histopatolojik tümör tipleri patolojik tümör boyutlarına göre karşılaştırıldığında, invaziv adenokarsinom görülme sıklığının artan tümör boyutu ile anlamlı şekilde arttığı tespit edildi (p

Prognostic factors for stage I lung adenocarcinoma and surgical management of subsolid nodules

Background: This study aims to identify the prognostic factorsfor stage I lung adenocarcinoma and to evaluate the surgicalmanagement of subsolid nodules.Methods: The study included 133 patients (90 males, 43 females;mean age 64.9 years; range, 29 to 82 years) who had undergoneoperation in our clinic for stage I lung adenocarcinoma betweenJanuary 2007 and December 2015. Clinical, radiological andpathological data were retrospectively evaluated and their effectson recurrence and survival were examined by Kaplan-Meier andCox regression analyses.Results: Comparing the histopathological tumor types accordingto the pathological tumors size, we determined that the prevalenceof invasive adenocarcinoma significantly increased with increasingtumor size (p

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