Kemik İyileşmesinde hyaluronik asitin etkinliğinin değerlendirilmesi: derleme

Kemik defektleri; tümör cerrahisi, kist enükleasyonları, enfeksiyonlar, konjenital ve gelişimsel malformasyonlar, travma, kist enükleasyonları gibi çeşitli nedenlerle oluşabilmektedir. Kemik defektlerinin onarımında çeşitli greft materyalleri, distraksiyon ve yönlendirilmiş doku rejenerasyonu gibi teknikler uygulanmaktadır. Özellikle boyutları artan kemik defektlerinin iyileşme süresinin uzun olması, bu defektlerde estetik ve fonksiyonel olarak tam bir onarımın zorluğu araştırmacıları bu süreci hızlandırmak ve uygulanan tekniklerin etkinliğini arttırmak için yeni materyal arayışlarına yönlendirmiştir. Bu derleme çalışmasında, hyaluronik asitin kemik iyileşmesine olan etkilerinden ve hyaluronik asitle yapılan hayvan deney çalışmalarındaki etkinliğinden bahsedilecektir.

Anahtar Kelimeler:

Hyaluronik asit, kemik iyileşmesi

Evaluation the efficacy of hyaluronic acid in bone healing: review

Bone defects; Tumor surgery, cyst enucleations, infections, congenital and developmental malformations, trauma, cyst enucleations. Techniques such as various graft materials, distraction and directed tissue regeneration are applied to repair bone defects.In particular, the length of the healing period of bone defects, which are increasing in size, and the difficulty of a complete aesthetic and functional repair of these defects, have prompted researchers to search for new materials in order to accelerate this process and increase the effectiveness of applied techniques. This review study will discuss the effects of hyaluronic acid on bone healing and the effectiveness of animal experiments with hyaluronic acid.

Keywords:

Hyaluronic acid, bone healing,

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