Mustafa DURGUN, Emre İNÖZÜ, Ali Teoman TELLİOĞLU, Avni Tolga ERYILMAZ, Enver ARPACI, Uğur HOROZ

Bazal hücreli karsinom: 5 yıllık deneyim

Amaç: Bazal hücreli karsinom en sık görülen kanser türüdür. En sık pilosebase bezlerin yoğun olduğu ve güneşe maruziyetin belirgin olduğu baş-boyun bölgesinde görülür. Yavaş büyür, lokal invazyon gösterir ve uzak metastazı nadirdir. Cerrahi olarak tümörün çıkartılması ve histolojik olarak cerrahi sınırların temiz olduğunun gösterilmesi ile tedavi sağlanır. Yöntem ve Gereçler: Kliniğimizde 2006 - 2011 yılları arasında bazal hücreli karsinom nedeniyle cerrahi tedavi uygulanan 436 vaka retrospektif olarak değerlendirilmiştir. Hastaların yaşı, cinsiyeti ile tümörün boyutu, anatomik lokalizasyonu, histolojik alt tipi kaydedildi. Cerrahi sınır pozitifliği ve nüks oranları belirlendi. Bulgular: Hastaların ortalama yaşı 58,4 idi. Lezyonların büyük kısmı yüz bölgesinde (%82,6) lokalizeydi. En sık nodüler tip görülürken, en fazla nüks infiltratif tipte izlendi. Histopatolojik inceleme sonucunda 29 hastada (%6,7) cerrahi sınır pozitifliği görüldü. Ortalama 30,6 ay takip edilen hastaların 13’ünde (%3,4) nüks, 6’sında (%1,6) yeni oluşan bir bazal hücreli karsinom izlendi. Sonuç: Bazal hücreli karsinomların cerrahi tedavisinin başarısında eksizyon sınırlarının doğru olarak belirlenmesi önemlidir. Bunun için risk faktörleri iyi değerlendirilmelidir. Histolojik tip cerrahın tedavi yaklaşımını, dolayısıyla olası nüks oranını etkilemektedir.

Basal cell carcinoma: 5 years of experience

Aim: Basal cell carcinoma is the most common form of cancer. It usually occurs at sites with the greatest concentration of pilosebaceous follicles, and it is directly related to sun exposure. It grows slowly and shows local invasion but distant metastases is rare. The complete excision of basal cell carcinoma and histological confirmation of tumor clearance allows disease control. Material and Methods: The present group of 436 cases surgically treated between 2006 and 2011 in our department were retrospectively analyzed. Patient and tumor characteristics recorded were: age, gender, tumor size, anatomic location, histologic subtype, excisional margins and recurrence rate. Results: The mean age of the patient was 58,4 years. The lesions were primarily localized to the face (82.6%). The most frequent histological type was the nodular. Infiltrative type had a high recurrence rate. The average follow-up period in this report was 30.6 months. Incomplete excisions occurred in 21(6.7%) cases. The rate of basal cell carcinom recurrence was 3.4% (13 cases). Conclusion: The success of surgical treatment of basal cell carcinoma is essential to determine the correct exicional boundaries. Also risc factors must be evaluated. Histological type influence the surgical treatment and rate of recurrence.

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