Murat ULUTAŞ, Haydar SEKMEN, Mehmet SEÇER, Soner ŞAHİN

Subaraknoid kanama sonrası erken beyin hasarı

Subaraknoid kanama, dünya nüfusu göz önüne alındığında en önemli morbidite ve mortalite nedenlerinden biridir. Geç komplikasyonların (tekrar kanama,hidrosefali,geç iskemik nörolojik defisit,elektrolit imbalansı) yönetimi,sonuçların daha iyi olmasını sağlayabilir. Fakat,serebral hemodinamiğin apopitoz patofizyolojik süreçler, önlenemeyen erken heyin hasarına subaraknoid kanama sonrası serebral kan akımının önemi ve erken beyin hasarına yol açan patofizyolojik mekanizmalar özetlenmiştir.

Early brain injury after subarachnoidal hemorrhage

Subarachnoidal hemorrhage is one of the most important causes of mortality and morbidity among the world's population. Management of late hydrocephaly, late ischemic neurological deficit, or electrolyte imbalance) can improve outcomes. However, pathophysiological processes, such as deterioration development of vascular-neuronal apoptosis, and genetic factors that occur with the hemorrhage, lead to early brain injury that cannot be prevented. In this review, the significance of the cerebral hemorrhage and pathophysiological mechanisms that lead to early brain injury are summarized.

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