Mitral kapak replasmanı sonrasında pulmoner fonksiyonlarda uzun dönem takipte ortaya çıkan değişiklikler

Amaç: Bu çalışmada, mitral kapak hastalığı nedeni ile mitral kapak replasmanı uygulanmış hastalarda pulmoner fonksiyonlardaki değişikliklerin geri dönüşümlü olup olmadığını Gereç ve yöntem: Kliniğimizde Ocak 2008 ile Haziran 2011 tarihleri arasında mitral kapak replasmanı uyguladığımız 26 hasta değerlendirildi. Aort yetersizliği, koroner arter hastalığı, kronik obstrüktif akciğer hastalığı olan hastalar çalışmaya alınmadı. Hastaların demografik özellikleri, ekokardiyografi bulguları, spirometrik solunum fonksiyon test sonuçları kaydedildi. İstatistiksel analiz için SPSS for Windows 10.0 (statistical package for social sciences) programı Bulgular: Çalışmaya alınan hastalar retrospektif olarak değerlendirildi. FVC, FEV1, FEV1/FVC, FEF 25-75 %, PEF değerleri pre ve postoperatif olarak karşılaştırıldı. p

Alterations of pulmonary functions occuring after mitral valve replacement in long-term follow-up

Objective: In this study, we aimed to evaluate the reversibility of the alterations of pulmonary functions in the group of patients who underwent mitral valve surgery due to mitral valve disease. Methods: In this study, 26 of patients were evaluated who underwent mitral valve replacement in our clinic between January 2008 and June 2011. The patients with aortic regurgitation, coronary artery disease, chronical obstructive lung disease were excluded. Patients' demographic findings and spirometrical pulmonary function test results were recorded. SPSS (statistical package for social sciences) for Windows 10.0 programme was used for statistical analysis. Results: Study group of patients were evaluated retrospectively. FVC, FEV1, FEV1/FVC, FEF 25-75 %, PEF values were compared pre and postoperatively. We considered p<0,001 as statistically significant. All measures we evaluated were statistically significant. Conclusion: We concluded that the important part of the pulmonary dysfunctions due to mitral valve disease are reversible.

___

  • 1.Roberts WC. Morphologic aspects of cardiac valve dysfunction. Am Heart J 1992; 123:1610-17.
  • 2.Schwartz R, Myerson RM, Lawrence LT, et al. Mitral stenosis, massive pulmonary hemorrhage, and emergency valve replacement. N Engl J Med 1966; 275:755-67.
  • 3.Carabello BA. Timing of surgery in mitral and aortic stenosis. Cardiol Clin 1991; 9:229-41.
  • 4.Hygenholtz PG, Ryan TJ, Stein SW, et al. The spectrum of pure mitral stenosis. Am J Cardiol 1962; 10:773-96.
  • 5.Alaa-Basiouni SM, Mohamed SB, Ali AH, et al. Effect of modified ultrafiltration on pulmonary function aftercardiopulmonary bypass. Chest 2005; 128:3447-53.
  • 6.Kirklin JK, Blackstone EH, Kirklin JW. Cardiopulmonary bypass: Studies on its damaging effects. Blood Purif 1987; 5:168-87.
  • 7.Ohno K, Nakahara K, Hirose H, et al. Effect of valvular surgery on overall and regional lung function in patients with mitral stenosis. Chest 1987; 92:224-28.
  • 8.Rhodes KM, Evemy K, Nariman S. Effects of mitral valve surgery on static lung function and exercise performance. Thorax 1985; 40:107-12.
  • 9.Techniques of evaluating pulmonary function in patients with cardiac disease in Hurst's The Heart, 8th ed., Schlant RC, Alexander RW, New York, McGraw-Hill, 1994; 441-45.
  • 10.Wood T, McCleod P, Anthonisen NR. Mechanics of breathing in mitral stenosis. Am Rev Resp 1971; 104:52-60.
  • 11.Rolla G, Bucca C, Caria E. Bronchial responsiveness in patients with mitral valve disease. Eur Respir J 1990; 3:127-31.
  • 12.Snashall P, Chung KR. Airway obstruction and bronchial hyperresponsiveness in left ventricular failure and mitral stenosis. Am Rev Dis 1991; 144:945-55.
  • 13.Nushimura Y, Maeda H, Yokoyama M. Bronchial Hyperreactivity in patients with Mitral Valve Disease. Chest 1990; 98:1085-90.
  • 14.Hryniewiecki T, Rawczynska I, Malinowski R. Analysis of airway function in patients with mitral valve disease in various stages of progression. Przegl Lek 1999; 56:270-75.
  • 15.Cieslewicz G, Juszezyk G, Foremmy J. Inhaled corticosteroid improves bronchial reactivity and decreases symptoms in patients with mitral stenosis. Chest 1998; 114:1070-74.
  • 16.Valvular heart disease in Heart Disease: A textbook of cardiovascular medicine, 2nd ed., Braunwald E, Philadelphia, WB Saunders Company, 1995; 1007-26.