The importance of endometrial biopsy in the evaluation of fertility potential of mares in raise horses in Turkey
Çalışmanın amacı, kısraklarda biopsi yöntemi ile endometrial patolojik değişimleri belirlemek, yaygınlığına ve şiddetine göre kategorize etmek, ve bu değişi mlerin yaş ve fertilite ile ola n ilişkisini belirlemektir. Biopsiler en az 2 yıld ır doğuramayan 53 k ısraktan siklusun fark lı dö nemler inde al ındı. Fibr osis (%73.6) ve kr onik infiltratif değ işimler (%50.9) e n yaygın o lmak üzere kısr akların %92.3’ ünde çeşitli endom etrial patolo jik değişimlere rastlandı. Kategorilerde her yaştan kısrak mevcuttu. Endometrial patolojik değişimlere göre 4 kısrak kategori-I, 7 kısrak kat egori-IIa, 10 kıs rak kategori-IIb ve 32 kısrak kateg ori-III grubuna dahil edildi. Biopsi alımından sonraki üreme sezonunda kate gori I, I Ia, IIb ve I II grubu k ısraklar için elde edilen doğum oranları sırası ile %75, 42.6, 10 ve 0 olarak bel irlendi. Sonuçlar, histolojik kategorilerle doğum oranları arasında belirgin bir iliş ki olduğun u gösterme ktedir ve bu neden le de fertilit enin değerl endirilmesinde endometrial biopsin in klinik olarak kullanımının önem taşıdığını göstermektedir.
Türkiye' deki yarış atlarında fertilitenin değerlendirilmesinde endometrial biopsinin önemi
The aim of this study was to detect pathological changes in the endometrium of mares with the endometrial biopsy technique and to classify these changes according to distribution and severity, and finally to investigate the relation of these changes to age and foaling rates. Biopsies were obtained from 53 mares which had not foaled for at least two years who were at different stages of the estrous cycles. Pathological endometrial changes were observed in 92.3 percent of mares with the majority having fibrosis (73.6%) and chronic infiltrative changes (50.9%). All categories included mares of different ages. Four mares were classified as category-I, 7 as category IIa, 10 as category-IIb and 32 as category-III. The foaling rate obtained for categories-I, IIa, IIb and III were 75, 42.8, 10 and 0% respectively for the breeding season following the collection of endometrial biopsy. It is apparent from the data that there is a meaningful association between histological categories and foaling rate indicat ing that endometria l biopsy should be used as a diagnostic technique in the evaluation of fertility potential of mares.
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