ALİ HAYDAR KIRMIZIGÜL, MAHİR KAYA, Ali BUMİN, ASLAN KALINBACAK

Evaluation of resistive index parameter in peritoneal dialysis in dogs with experimental bilateral proximal ureteral obstruction

Bu çalışmada, bilateral proksimal üreteral obstrüksiyon oluşturulan köpeklerde, Renkli Doppler Ultrasonografi (RDUS) ile böbreklerdeki patolojik değişiklikler ve fizyolojik parametrelerin bir göstergesi olan Rezistiv İndeks (Rİ) değerindeki değişikliklerin belirlenmesi amaçlandı. Çalışmada 3 dişi, 3 erkek olmak üzere toplam 6 melez köpek kullanıldı. Hayvanlarda, genel anestezi altında deneysel laparatomi yapılarak, bilateral proksimal üreteral obstrüksiyon oluşturuldu. Kanda artan metabolitlerin uzaklaştırılması için peritoneal diyaliz uygulandı. Obstrüksiyon oluşturulmadan önce ve sonra, peritoneal diyaliz sırasında ve üreterlerdeki klipsler çıkarıldıktan sonra 5, 10 ve 15. günlerde böbreklerin RDUS ve Gri Skala Ultrasonografi (GSU) ile muayeneleri yapıldı. RDUS ile elde edilen Rİ değerlerinin peritoneal diyaliz sırasında yükselmediği belirlendi. Sonuç olarak, RDUS ve GSU kombinasyonunun böbrek hastalıklarının değerlendirilmesinde faydalı olduğu ve obstrüktif renal hastalıklarda Rİ artışının peritoneal diyaliz ile önlenebileceği belirlendi.

Anahtar Kelimeler:

deneysel cerrahi, köpek, diyaliz, böbrekler, ultrasonografi

Deneysel bilateral proksimal üreteral obstrüksiyon oluşturulan köpeklerde peritoneal diyaliz uygulamasında rezistiv indeks parametresinin değerlendirilmesi

In this study, resistive index (RI) value that reflects pathologic and physiologic changes in kidneys was investigated after experimental bilateral proximal ureteral obstruction in dogs by Color Doppler Ultrasonography (CDUS). Six mongrel dogs (3 females and 3 males) were used. Bilateral proximal ureteral obstruction was formed interventionally by laparatomy. Peritoneal dialysis was performed for the clearence of metabolites increased in the blood. Kidneys were examined by CDUS and Gray Scala Ultrasonography (GSU) before and after laparatomy, during the peritoneal dialysis, and the 5th, 10th, and 15th days after removal of the clips from the ureters. RDUS revealed that RI values were not increased during the peritoneal dialysis. In conclusion, combination of GSU and CDUS is helpful in evaluation of renal diseases, and increased RI value in obstructive renal diseases can be obviated by peritoneal dialysis.

Keywords:

experimental surgery, dogs, dialysis, kidneys, ultrasonography,

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