SADIK YAYLA, CİHAN KAÇAR, ENGİN KILIÇ, SEMRA KAYA, MUSHAP KURU, CELAL ŞAHİN ERMUTLU, İSA ÖZAYDIN, Ürfettin HÜSEYİNOĞLU, METİN ÖĞÜN

The Effects of Intrathecal Administration of Bupivacaine or Ropivacaine Following Administration of Propofol in Dogs Undergoing Ovariohysterectomy

Bu çalışmanın amacı ovariohisterektomi operasyonu yapılan köpeklere propofol verildikten sonra bupivacaine ve ropivacaine'in intratekal (IT) uygulamasının karşılaştırılması idi. Randomize ve prospektif olan bu klinik araştırmada 16 köpeğe propofol verildikten sonra IT anestezi lumbosakral boşluğa verilen ya 20 mg bupivacaine (Bupivacaine Grubu, BG, n=8) ya da 30 mg ropivacaine (Ropivacaine grubu, RG, n=8) ile sağlandı. Propofol uygulamasından sonra ve IT enjeksiyondan sonraki 150. dakikaya kadar noninvaziv olarak sistolik, diastolik ve ortalama arteriyel kan basınçları ile nabız, solunum sayısı ve rektal ısı kayıt edildi. Ovariohisterektomi operasyonu sırasında sensorik blokajın başlangıcı, süresi ve derinliği iğne pikürü ile yeterli derinlikte anestezi olup olmadığı değerlendirildi. Anestezi süresi (BG: 89.5±7.6 dk; RG: 64.75±6.8 dk) bakımından gruplar arasında istatistiki olarak önemli derecede bir farklı bulundu (P

Ovariohisterektomi Yapılan Köpeklerde Propofol Uygulamasını Takiben Bupivacaine ya da Ropivacainin İntratekal Uygulamasının Etkileri

The aim of this study was to compare intrathecal (IT) administration of bupivacaine and ropivacaine after propofol was given to dogs undergoing ovariohysterectomy operation. After propofol was administered to 16 dogs, IT anesthesia was performed with either 20 mg of bupivacaine (bupivacaine group, BG, n=8) or 30 mg ropivacaine (ropivacaine group, RG, n=8) in the lumbosacral space in this randomized, prospective, clinical trial. Noninvasively systolic, diastolic and mean arterial blood pressure, heart rate, respiratory rate and rectal temperatures were recorded after propofol and up to 150 min after IT injections. Onset, duration and the extent of sensory block were determined by using the needle prick during the ovariohysterectomy operation. The duration of IT anesthesia (BG: 89.5±7.6 min; RG: 64.75±6.8 min) was significantly different between the groups (P<0.05). The values in each group were within the reference range although there were differences in terms of arterial blood pressure (systolic, diastolic and mean), heart rate, respiratory rate and rectal temperatures. In conclusion, this study showed that IT bupivacaine and ropivacaine following administration of propofol can provide safe and effective anesthesia in dogs undergoing ovariohysterectomy operations

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