Aynur DEMİR, Dilek OLGUN ERDİKMEN, Zeynep TOL SEVİM, Yusuf ALTUNDAĞ

Kedilerde Desmatoselin Eşlik Ettiği Derin Kornea Ülserlerinde PRF Membran Kullanılarak Cerrahi Tedavinin Değerlendirilmesi: Retrospektif Çalışma (2019- 2021)

Sunulan bu çalışmada kedilerde desmatoselin eşlik ettiği derin kornea ülserlerinde yeni nesil trombositten zengin fibrin (PRF) membran greft i uygulamasının oküler yüzey rekonstrüksiyonu cerrahisindeki sonuçları değerlendirildi ve Mayıs 2019 ile Ağustos 2021 arasını kapsayan retrospektif karşılaştırmalı olmayan bir çalışma yapıldı. Kornea ülseri olan hastalara rutin cerrahi prosedürlerin ardından ülser bölgesine yeni nesil otolog PRF membran greft i nakledildi. Çalışmada on dokuz göz değerlendirildi (14 erkek, beş dişi). Tedavi sonrası tüm olgularda korneanın bütünlüğü ve gözde görme sağlandı. 10. günden itibaren tüm kedilerde göz içi basıncı ölçümü yapıldı ve tonometre oküler tonus seviyelerini rahatlıkla belirledi. Membran transplantasyonundan sonra herhangi bir enfeksiyon veya yangı belirtisi tespit edilmedi. PRF membran dikişlerle kornea defekt bölgesine nakledildi ve kusurun aciliyetini ortadan kaldırma, korneayı destekleme ve korneal iyileşmeyi hızlandırmada etkili olduğu belirlendi. PRF membranının kornea entegrasyonu, postoperatif ayrılma veya gerilme olmaksızın tüm vakalarda başarılı olduğu görüldü. PRF membran greft inin uygulandığı bu serideki desmatoselli olgularda elde edilen %89.4 başarı oranı ile kedilerde derin kornea ülserlerinin cerrahi tedavisinin yönetiminde diğer kornea rekonstrüksiyon yöntemlerine benzer şekilde güvenli ve etkili olarak kullanıldığı bulundu.

Evaluation of Surgical Treatment Using PRF Membrane in Deep Corneal Ulcers Accompanied by a Descemetocele in Cats: Retrospective Study (2019-2021)

In the present study, the results of the new generation platelet-rich fibrin (PRF) membrane graft application in deep corneal ulcers accompanying descemetocele in cats in ocular surface reconstruction surgery were evaluated, and a retrospective non-comparative study covering the period between May 2019 and August 2021 was conducted. Patients underwent routine surgical procedures for corneal ulcers, and then a new-generation autologous PRF membrane graft was transplanted to the ulcer site. Nineteen eyes were analyzed (14 males, five females). Corneal integrity and vision were achieved in all cases aft er treatment. No signs of infection and infl ammation were noted aft er membrane transplantation. Th e PRF membrane was transplanted to the defected area with sutures generating highly eff ective results in eliminating the defect’s urgency, supporting the cornea, and accelerating the corneal healing. Corneal integration of the PRF membrane was successful in all cases without postoperative separation or stretching. In conclusion, the PRF membrane graft ing was safely and eff ectively utilized in the surgical treatment of deep corneal ulcers in cats with a success rate of 89.4% in descemetocele cases.

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