Gizem TEZ, Eray ALÇIĞIR, HALİT KANCA

Bir Kedide Kısmi Hidatidiform Mol Nedeniyle Gebelik Kaybı

Hayvanlarda plasentanın molar değişiklikleri son derece nadir olup kedilerde yalnızca ölü doğan bir yavruda kısmi hidatidiform mol olgusu bildirilmiştir. 3 yaşlı dişi bir kedi iştahsızlık, kusma, durgunluk ve vaginal akıntı şikayetleri ile getirildi. Abdominal gerginlik ve ağrı kaydedildi. Kedide ayrıca kan sayımı anormallikleri gözlendi. Ultrasonografik muayenede anekojenik içeriğe sahip, septumlu, genişlemiş uterus belirlendi. Ventral orta hattan ovaryohisterektomi yapıldı. Hızlı bir iyileşme gözlendi ve ovaryohisterektomiyi takiben 3. günde tam kan sayımı değerleri normale döndü. Embriyoların bulunması, makroskobik görünüm ve histopatolojik bulgulara dayanılarak kısmi hidatidiform mol tanısı konuldu. Bu raporda, bir kedide gebelik kaybı ile sonuçlanan kısmi hidatidiform mol olgusunun klinik görünümü ve histopatolojik bulguları tanımlanmıştır.

Pregnancy Loss due to Partial Hydatidiform Mole in a Cat

Molar changes of the placenta are exceptionally rare in animals and in the cat, only one case of partial hydatidiform mole in a stillborn kitten was reported. A 3-year-old female cat was referred for anorexia, vomiting, depression and vaginal discharge. Abdominal distention and pain were noted. Blood count abnormalities were also observed in the cat. A septated, enlarged uterus with anechogenic content was diagnosed on ultrasonographic examination. Ventral midline ovariohysterectomy was performed. An uneventful recovery was observed and total blood count was within normal range on day 3 following ovariohysterectomy. Partial hydatidiform mole diagnosis was made based on the presence of embryos, gross appearance and histopathological findings. This report reflects the clinical presentation and histopathological findings of a partial hydatidiform mole leading to pregnancy loss in the cat.

PDF

___

Altieri A, Franceschi S, Ferlay J, Smith J, La Vecchia C: Epidemiology and aetiology of gestational trophoblastic diseases. Lancet Oncol, 4, 670- , 2003. DOI: 10.1016/S1470-2045(03)01245-2
Deep JP, Sedhai LB, Napit J, Pariyar J: Gestational trophoblastic disease. J Chitwan Med College, 3, 4-11, 2013. DOI: 10.3126/jcmc.v3i2.8434
Monchek R, Wiedaseck S: Gestational trophoblastic disease: An overview. JMWH, 57, 255-259, 2012. DOI: 10.1111/j.1542-2011.2012.00177.x
Mazur MT, Kurman RJ: Gestational trophoblastic disease. In, Diagnosis of Endometrial Biopsies and Curettings: A Practical Approach, 2nd ed., 99, Springer-Verlag, New York, 2005.
Gopal T, Leipold HW, Dennis SM: Hydatidiform moles in Holstein cattle. Vet Rec, 107, 395-397, 1980. DOI: 10.1136/vr.107.17.395
Meinecke B, Kuiper H, Drögemüller C, Leeb T, Meinecke-Tillmann S: A mola hydatidosa coexistent with a foetus in a bovine freemartin pregnancy. Placenta, 24, 107-112, 2002. DOI: 10.1053/plac.2002.0872
Morris FJ, Kerr SM, Laven RA, Collett MG: Large hydatidiform mole: an unusual finding in a calving cow. N Z Vet J, 56, 243-246, 2008. DOI: 1080/00480169.2008.36841
Jurka P, Sacharczuk M, Kawka M, Sobczak-Filipiak M, Golicz M: Partial hydatidiform mole diagnosis in a cat: A case report. J Feline Med Surg, 16, 180-182, 2014. DOI: 10.1177/1098612X13496247
Zambelli D, Castagnetti C, Belluzzi S, Bassi S: Correlation between the age of the conceptus and various ultrasonographic measurements during the first 30 days of pregnancy in domestic cats (Felis catus). Theriogenology, 57, 1981-1987, 2002. DOI: 10.1016/S0093-691X(01)00686-0
Monga A: Gynaecology by Ten Teachers. 18th edn., 89-102, CRC Press, Florida, 2006.