Acute kidney injury due to rhabdomyolysis after status epilepticus: Two pediatric case reports
Rabdomiyoliz, travmatik veya non-travmatik sebeplerle çizgili kas hücrelerinin hasara uğramasıdır. Hasar sonrası kas hücre içeriği (miyoglobin, enzim ve elektrolitler) dolaşıma katılır. Rabdomiyoliz teşhis ve tedavi edilmezse akut böbrek hasarı (ABH), hipokalsemi, hiperkalemi, hipovolemi, kas nekrozu, kardiyak aritmi ve kompartman sendromu gibi ciddi komplikasyonlara neden olabilir. Status epileptikus, rabdomiyoliz ve miyoglobinürinin nadirsebeplerindendir. Bu yazıda status epileptikus sonrası miyoglobinüri ve ABH gelişen iki pediatrik olgu sunulmuştur.
Status Epileptikusa bağlı rabdomiyoliz ve akut böbrek hasarı: İki pediatrik olgu sunumu
Rhabdomyolysis is defined as degeneration of skeletalmuscle due to traumatic or non-traumatic causes. Withthe injury of sarcolemma, myocyte contents (myoglobin,enzymes and electrolytes) leakage into the plasma andurine occurs. If rhabdomyolysis is not recognized and untreated, severe even fatal complications such as acutekidney injury (AKI), hypocalcemia, hyperkalemia, hypovolemia, muscle necrosis, cardiac arrythmias and compartment syndrome may occur. Status epilepticus is anuncommon cause of rhabdomyolysis and myoglobinuria.We report here two pediatric patients, who developedmyoglobinuria and AKI due to status epilepticus.
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