Multipl primer tümörler (İki olgu sunumu)

Amaç: Akciğer kanserlerinin seyrinde metastazlar daha sık görülmekle birlikte ender rastlanılan multipl primer tümörlerin tanımlanması amaçlanmıştır. Olgu sunumu: Biri akciğer ve cilt altı, diğeri akciğer ve böbrek yerleşimli eşzamanlı olarak saptanan multipl primer tümörlü iki olgu sunuldu. Cerrahi rezeksiyon uygulanan olgulardan ilkinde histopatoloji; akciğerde adenokarsinom ile gluteal bölgede cilt altında miksoid liposarkom, ikincisinde ise akciğerde küçük hücreli karsinom ve böbrekteki hipernefroma idi. Tedaviyi takiben 1. olgu 20 aydır tümörsüz ve sağlıklı yaşamını sürdürürken 2. olguda ise adjuan kemoterapiyi takiben 16. ayda serebral ve multipl akciğer metastazları saptandı. Sonuç: Eşzamanlı saptanan bu tümörlerin gerek lokalizasyonları gerekse histopatolojik kombinasyonları dolayısıyla ender rastlanmaları nedeniyle, multipl primer tümörler literatür ışığında gözden geçirilmiştir.

Anahtar Kelimeler:

Karsinom, renal hücreli, Akciğer neoplazmları, Neoplazmlar, multipl primer, Adenokarsinom, bronşiyolo-alveolar, Liposarcom, Karsinom, küçük hücreli, Erkek, Erişkin

Multiple primary tumors (Report of two cases)

Objective: it was aimed to report rare multiple primary tumors, however, its metastases in the course of pulmonary carcinomas are more common. Case report: Two patients with multiple primary tumors, synchronous pulmonary/subcutaneous tumors in the first case and pulmonary/kidney tumors in the second were introduced. Ali tumors were treated surgically. Histopathological examination of the first case showed combination of adenocarcinoma in the right lung and myxoid liposarcoma in the right buttock, and the second case showed the right pulmonary small cell carcinoma and hypernephroma in the left kidney. After the surgical treatment, survival of the first case was 20 months without any recurrence. Although adjuvant chemotherapy was performed on the second case, widespread metastases were found in the postoperative 16th month. Conclusion: Synchronous multiple primary tumors are very rare in these localizations with these histopathological combinations. For this reason in this article they were reviewed in the light of literature.

Keywords:

Carcinoma, Renal Cell, Lung Neoplasms, Neoplasms, Multiple Primary, Adenocarcinoma, Bronchiolo-Alveolar, Liposarcoma, Carcinoma, Small Cell, Male, Adult,

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ISSN: 2602-3741
Yayın Aralığı: Yılda 6 Sayı
Başlangıç: 1997
Yayıncı: SELÇUK ÜNİVERSİTESİ > TIP FAKÜLTESİ

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