Olga NABOKA, Olga FİLİPTSOVA, Marina KOBETS, Yulia KOBETS

Ukrayna’da Farmakogenetik Testler: Ekonomik Bakış

Amaç: Modern tıpta anahtar bir yaklaşım;bireysel hastanın spesifik özelliklerine dayalı olarak ilaç ve doz seçim taktiklerini kullanmak ve organizmanın genetik özelliklerine dayalı tedavi rejimlerini belirlemektir. Bu yaklaşım, bireysel tıbbın bir parçasıdır ve farmakogenetik testlere dayanmaktadır. Farmakogenetik testlerin yürütülmesinin gerçek imkanlarını incelemek için Ukrayna nüfusunun araştırılması ilk kez gerçekleştirildi ve DNA testlerini gerçekleştirmenin ekonomik boyutu da incelendi. Yöntem: Bu çalışmada saha araştırmaları yapılmıştır. Ukrayna'da Eczacılık, Tıp ve Biyoloji gibi yüksek öğretimde öğrenim gören öğrenciler ile Tıp ya da Eczacılık alanıyla ilgisi olmayan kişiler de sorgulandı. Çalışmamızda 3143 katılımcı yer aldı. Bulgular: Farklı meslek gruplarında görüşülen erkek ve kadınların üçte birinin tedavinin maliyetine bağlı olarak test için ödeme yapmaya hazır olduğu tespit edilmiştir. Katılımcıların yarısından fazlasının (%71.8 erkek ve %78.6 kadın) önemli bir yatırım gerektirmesine rağmen Ukrayna'da DNA testleri yapılabileceğini düşündüğü saptanmıştır. Sonuç: Ukrayna'da ekonomik açıdan dikkate alınarak farmakogenetik test yapma fırsatları incelenmiştir. Çalışmalar, klinik uygulamaya daha ileri farmakogenetik testlerin getirilmesi amacıyla Ukrayna nüfusu için farmakogenetik testler hakkındaki farkındalığının arttırılması gerektiğini gösterdi.

Pharmacogenetic Tests in Ukraine: Economic Aspect

Background: A key approach in modern medicine is the use of tactics ofchoosing drugs and their doses based on the specific characteristics of theindividual patient, as well as determination of treatment regimens based onthe genetic traits of the organism. This approach is part of personalizedmedicine and is based on pharmacogenetic testing. To study the realpossibilities of conducting pharmacogenetic tests the questioning of thepopulation of Ukraine has been performed for the first time, and theeconomic aspect of carrying out DNA tests has been studied.Methods: Field investigations were used in this work. The students ofpharmaceutical, medical and biological specialties of higher schools ofUkraine, the medical staff, as well as persons having no relevance to the fieldof medicine or pharmacy were questioned. In our study 3143 respondentstook part.Results: It has been determined that one third of the males and femalesinterviewed in different occupational groups are ready at the moment to payfor testing depending on the cost of treatment. It has been shown that morethan half of the respondents (71.8% males and 78.6% females) consider itpossible to conduct DNA tests in Ukraine although it requires a significantinvestment.Conclusion: The opportunities of conducting pharmacogenetic testing inUkraine taking into account the economic aspect have been studied. Thestudies have shown that it is necessary to raise the awareness of thepopulation of Ukraine about pharmacogenetics with the purpose of furtherintroduction of pharmacogenetic testing into clinical practice.

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