Melih ŞAHİN, Mehmet DÜZLÜ, Levent OKTAR, Metin YILMAZ, Baran ÖNAL, Hakan TUTAR, Recep KARAMERT, Furkan KARALOĞLU, Murat UÇAR

Karotis Cisimciği Paragangliomalarında Cerrahi Deneyimimiz ve Literatür Derlemesi

Amaç: Karotis cisimciği paragangliomu (KCP), nöral krest kaynaklı benign birtümördür ve genellikle yavaş seyreder. Tedavide cerrahi ve radyoterapiseçenekleri mevcuttur. Bu çalışma ile KCP hastalarında cerrahi sonuçlarımızısunmayı ve literatür verileriyle karşılaştırmayı amaçladık.Metod: Kliniğimizde 2004-2016 yılları arasında KCP nedeniyle ameliyat edilen24 hasta retrospektif olarak çalışmaya dahil edilmiştir. Hasta dosyaları,radyolojik bulgular ve patoloji kayıtları demografik bilgileri ve perioperatifkomplikasyonları da içerecek şekilde detaylı olarak incelenmiştir.Bulgular: Hastaların 3’ü (% 12.5) erkek 21’i (% 87.5) kadındır ve yaşortalaması 44.4 ±13.6 bulunmuştur. Shamblin tümör grubu sınıflandırılmasıyapılabilen 17 hastanın 6’sında (% 35.3)Tip I, 8’inde (% 47.1) Tip IIve 3’ünde(% 11.6) Tip III olarak saptanmıştır. Yirmi-üç vakada(% 95.8)tümör totalolarak çıkarılmıştır. Takiplerde bir hastada tümör nüksü saptanmıştır. İkihastada ameliyata bağlı kalıcı kraniyal sinir hasarı (% 8.3), bir hastadahemipleji (% 4.2) ve bir hastada (% 4.2) preoperatif embolizasyona bağlıtransient iskemik atak (TİA) gelişmiştir.Sonuç: KCP’nin kesin tedavisi cerrahi eksizyondur. Fakat kraniyal sinir hasarıve nadiren de hemipleji gibi ciddi komplikasyon riskleri vardır. Bizimçalışmamızda da cerrahi başarı oranları oldukça iyi bulunmuş ve hastaların birkısmında literatür verileriyle uyumlu oranlarda çeşitli nörolojikkomplikasyonlar görülmüştür.

Our Surgical Experience on Carotid Body Paragangliomas and Literature Review

Aim: Carotid body paraganglioma (CBP) is a usually slow growing benign tumor originating from neural crest. Surgery and radiotherapy options are available for the treatment. In this study, we aimed to present our surgical results with KCP tumors and to compare them with literature data. Methods: Twenty-four patients who were operated for CBP in our clinic between the years 2004 and 2016 were included in the study. Patient charts, radiological findings and pathology records were examined in detail retrospectively, including demographic information and perioperative complications. Results: Three patients (12.5 %) were male and 21 (87.5 %) patients were female with the mean age 44.4 ± 13.6 years. The Shamblin group of tumors were found to be Type I in 6 (35.3 %), Type IIin 8 (47.1 %) and Type III in 3 (11.6 %) of the 17 patients who were available for classification. In 23 cases (95.8 %) the tumor was totally removed. On follow-up tumor recurrence was detected in one patient. Surgical complications were permanent cranial nerve injury in two patients (8.3 %) and hemiplegia in one (4.2%) patient. Transient ischemic attack (TIA) developed in one case (4.2%) due to preoperative embolization. Conclusion: The definitive treatment of CBP is surgical excision. However, there is risk forsome complications such as cranial nerve damage and rarely hemiplegia. In our study, the surgical success rate was found to be quite good and the rate of various neurological complications seen in some cases is also in compliance with the literature data.

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