Merih TEPEOĞLU, Ozgur GUNDUZ, Onder BOZDOGAN, Ilker YAZİCİ, Şebnem KUPANA AYVA

Eş Zamanlı Saptanan İki Kutanöz Kollizyon Tümör Olgusu

Kutanöz kollizyon tümörler, anatomik olarak yakın ancak birbirinden net sınırlarla ayrılan iki bağımsız tümördür. Biz burada aynı zamanda, farklı lokalizasyonlarda iki kutanöz kollizyon tümörü olan 83 yaşında bir kadın hastayı sunduk. Sol burun kanadında izlenen ilk kollizyon tümör skuamöz hücreli karsinom ve bazal hücreli karsinom’dan oluşmakta iken, ikinci kollizyon tümör sağ dudak kenarında izlenen Malign melanom (Clark Level IV) ve bazal hücreli karsinom idi. Kollizyon tümörler literatürde sıklıkla bildirilen, çok da nadir olmayan tümörler olmakla birlikte, bildiğimiz kadarıyla bu vaka aynı hastada eş zamanlı olarak saptanan iki kollizyon tümör birlikteliğini gösteren ilk vakadır.

A Case of Two Synchronous Cutaneous Collision Tumors

Cutaneous collision tumors are known as two independent tumors which areclose anatomically and separated from one another by well boundaries. We,herein report a 83-year-old female patient with two cutaneous collisiontumors in two different localizations at the same time. First cutaneouscollision tumor located on left ala nasi was squamous cell carcinoma andbasal cell carcinoma and second one located on the right commisure wascomposed of malignant melanoma (Clark Level IV) and basal cell carcinoma.However, the presence of collision tumors is not uncommon and is oftenreported in the literature, to the best of our knowledge, it is the first casewhich shows the association of two synchronous cutaneous collision tumorin the same individual.

PDF

___

Bhatia S, Estrada-Batres L, Maryon T, Bogue M, Chu D. Second primary tumors patient with cutaneous malignant melanoma. Cancer 1999;86:2014-20.
Hallaji Z, Rahimi H, Mirshams-Shahshahani M. Comparison of risk factors of single basal cell carcinoma with multiple basal cell carcinomas. Indian J Dermatol 2011;56:398-402.
Giorgi V, Sestini S, Alfaioli B, Carelli G, Carli P. Cutaneous collision tumour (melanocytic naevus, basal cell carcinoma, seborrhoeic keratosis): a clinical, dermoscopic and pathological case report. Br J Dermatol 2005;152:787-90.
Satter EK, Metcalf J, Lountzis N, Elston DM. Tumors composed of malignant epithelial and melanocytic populations: a case series and review of the literatüre. J Cutan Pathol 2009;36:211-9.
Papa G, Grandi G, Pascone M. Collision tumor of malignant skin cancers: A case of melanoma in basal cell carcinoma. Pathol Res Pract 2006;202:691-4.
Hirakawa E, Miki H, Kobayashi S, Nomura Y, Ohmori M. Collision tumor of cutaneaous malignant melanoma and basal cell carcinoma. Pathol Res Pract 1998;194:649-53.
Piérard GE, Fazaa B, Henry F, Kamoun MR, Piérard- Franchimont C. Collision of primary malignant neoplasms on the skin: the connection between malignant melanoma and basal cell carcinoma. Dermatology 1997;194:378-9.
Burkhalter A, White WL. Malignant melanoma in situ colonizing basal cell carcinoma. A simulator of invasive melanoma. Am J Dermatopathol 1997;19:303-7.
Belisle A, Gautier MS, Ghozali F, Plantier F, Wechsler J. A Collision Tumor Involving Basal Cell Carcinoma and Lentigo Maligna Melanoma. Am J Dermatopathol 2005;27:319-21.
Slaughter DP, Southwıck HW, Smejkal W. Field cancerization in oral stratified squamous epithelium; clinical implications of multicentric origin. Cancer 1953;6:963-8.