Hamdi Cihan EMEKSİZ, Sefa SAĞ, Ümmühan ÇAY, Melike AYAZ, Ulas Emre AKBULUT

Akut Viral Hepatit A Enfeksiyonuna Bağlı Gelişen Akut Taşsız Kolesistit: İki Olgu Sunumu

Akut taşsız kolesistit (ATK), taş ve safra çamuru olmaksızın safra kesesininenflamasyonudur. Gangren, perforasyon ve ampiyem gibi komplikasyonlarasebep olduğu için yüksek mortalite ve morbidite ile ilişkilidir. Altta yatanhastalığa göre medikal veya cerrahi tedavi uygulanabilir. Çocuklarda sepsis,şok, uzamış açlık, total parenteral nutrisyon, çoklu kan transfüzyonu ATKgelişimi için en önemli risk faktörleridir. Ayrıca akut viral hepatitlerin nadir birkomplikasyonu olarak ATK gelişebilir. Bu yazıda hepatit A virüs enfeksiyonusonucu akut kolesistit gelişen ve destekleyici tedaviyle tamamen düzelen ikiolgu sunulacaktır.

Acute Acalculous Cholecystitis Developing in Association with Acute Viral Hepatitis A Infection: Two Case Reports

Acute acalculous cholecystitis (AAC) is defined as the inflammation of the bile duct without stone or biliary sludge. It is associated with high mortality and morbidity since it may lead to complications such as gangrene, perforation and empyema. According to the underlying cause, medical or surgical treatment is performed. The most important risk factors for the development of AAC in children are sepsis, shock, prolonged fasting, total parenteral nutrition and multiple blood transfusions. Acute acalculouscholecystitis also can occur as a rare complication of acute viral hepatitis. This report describes acute cholecystitis in two cases which developed as a result of hepatitis A virüs infection and resolved completely with supportive management.

PDF

___

Ozaras R, Mert A, Yilmaz MH, et al. Acute viral cholecystitis due to hepatitis A virüs infection. J Clin Gastroenterol 2003; 37: 79-81
Kamath SR, Sathiyasekaran M, Raja TE, et al. Profile of viral hepatitis A in Chennai. Indian Pediatr 2009: 46: 642-3
Black MM, Mann NP. Gangrenous cholecystitis due to hepatitis A infection. J Trop MedHyg 1992; 95: 73-4.
Casha P, Rifflet H, Renou C, et al. Acalculous acute cholecystitis and viral hepatitis A. Gastroenterol Clin Biol 2000; 24: 591-2.
Portincasa P, Moschetta A, DiCiaula A, et al. Changes of gallbladder and gastric dynamics in patients with acute hepatitis A. Eur J Clin Invest 2001; 31: 617-22.
Mourani S, Dobbs SM, Genta RM, et al. Hepatitis A virus-associated cholecystitis. Ann Intern Med 1994; 120: 398-400.
Ryu JK, Ryu KH, Kim KH. Clinicalfeatures of acuteacalculouscholecystitis. J ClinGastroenterol 2003;36:166-9.
Tsakayannis DE, Kozakewich HP, Lillehei CW. Acalculous cholecystitis in children. J Pediatr Surg 1996; 31: 127-30
Kaya S, Eskazan AE, Ay N, et al. Acute Acalculous Cholecystitis due to Viral Hepatitis A. Case Rep Infect Dis 2013; 2013: 407182
Huffman JL, Schenker S. Acute acalculous cholecystitis: a review. Clin Gastroenterol Hepatol 2010; 8: 15-22.
Parlak E, Parlak M. Akut Viral Hepatit A Seyri Esnasında Görülen Akut Taşsız Kolesistit. Viral Hepatit Derg 2013; 19: 15
Prashanth GP, Angadi BH, Joshi SN, et al. Unusual cause of abdominal pain in pediatric emergency medicine. Pediatr Emerg Care 2012; 28: 560-1.
Yi DY, Chang EJ, Kim JY, et al. Age, Predisposing Diseases, and Ultrasonographic Findings in Determining Clinical Outcome of Acute Acalculous Inflammatory Gallbladder Diseases in Children. J Korean Med Sci 2016; 31: 1617-23.
Karkera PJ, Sandlas G, Ranjan R, et al. Acute acalculous cholecystitis causing gallbladder perforation in children. J Indian Assoc Pediatr Surg 2010; 15: 139-41.
Uluğ M, Yaman Y, Yapıcı F, Uluğ NC. Çocuk Yaş Grubu Akut Viral Hepatit A Olguları ve Komplikasyonlarının İrdelenmesi. Çocuk Enf Derg 2010; 4: 65-70