Sefa KELEKÇİ, Selma TOKUÇOĞLU, İsmet İNAN

Comparison of ethacridine lactate and misoprostol in second trimester medical abortion

Amaç: İkinci trimester medikal abortus için henüz ideal bir metod bulunmaması nedeni ile çalışmamızda ethacridine laktat ve misoprostol'ü oksitosin infilzyonu ile kombine ederek ve tek baslarına metodların etkinliğini ve emniyetini karşılaştırdık. Methodlar: Bu çalışma 1996-1999 yıllan arasında iki merkezde 168 ikinci trimester medikal abortus olgusunda yapıldı. Hastalar misoprostol (n=40), ethacridine laktat (n=34),. ethacridine laktat ve oksitosin (n-46) ve misoprostol ve oksitosin (n=48) gruplarına randomize edildi. Bulgular: Gruplar arasında başarılı abortus oranları açısından fark saptanamazken ortalama indüksiyon abortus misoprostol ve oksitosin grubunda daha kısa idi (p

İkinci trimester medikal abortus olgularında misoprostol ile ethacridine laktat'ın karşılaştırılması

Purpose: : The ideal method for second-trimester termination has yet to be defined. In. this study, our goal is to compare ethacridine lactate and misoprostol with or without oxytoein infusion in second trimester medical abortion cases. Methods: This prospective study vas performed on 168 women requiring second trimester medical abortions between 1996 and 1999 in two centers. Patients were randomly assigned to ethacridine lactate group (n=34), misoprostol group (n=40), ethacridine lactate combined with oxytoein infusion group (n-46) or. misoprostol combined with oxytoein infusion group (n=48). The mean induction-abortion time and successful abortion rates for each group were determined and compared by x and student t-test Results: There were no significant differences between the groups for successful abortion rates, whereas the mean induction-abortion time was shorter in the misoprostol and oxytoein infusion groups (p

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