Köpeklerin Atipik Endokrinal Dermatozu, Alopesi X

Alopesi X, köpeklerin genç yetişkin dönemlerinde görülen, yüksek progesteron, düşük androjen,değişken östrojen ve kortizolde hafif artışla seyreden, yangı ve kaşıntının gözlenmediği kıldöngüsünün durması ile karakterize bir dermatozdur. Alaska Malamutu, Çov-Çov, Keeshond,Norveç Elkhound, Pomeryan ve Samoyed ırkları hastalığa daha yatkınlık ve duyarlılıkgöstermektedir. Klinik bulgular dermatolojik bulguların yanısıra psikojenik olarak da ortayaçıkabilmektedir. Baş ve distal ektremite dışındaki bölgelerde alopesi, simetrik bilateral alopesi,hiperpigmentasyon ve travma sonrası kılların yeniden uzaması önemli klinik bulgulardır. Tanıdaanamnez, biyokimyasal parametreler ve dermatohistopatolojik bulgular temeldir. Ayırıcı tanıda,hiperadrenokortisizm, hipotroidizm ve kongenital alopesi gözönünde bulundurulmalıdır. Tedavidekastrasyon, melatonin, mitotan ve trilostan uygulamalarını kapsamaktadır. Son yıllarda, beşerîhekimlikte ve kozmetik endüstrisinde kullanılan mikroiğneleme yöntemi önem arz etmektedir.Sonuç olarak, hastalığın seyrine göre uygulanabilecek tedavi seçeneklerinin geliştirilmesi açısındandaha etkin tanısal yaklaşımlara ihtiyacın olduğu dikkati çekmektedir.

Atypical Endocrinal Dermatosis of Dogs, Alopecia X

Alopecia X is a type of dermatosis seen in young adult dogs and characterized by cessation of haircycle, high progesterone, low androgen, variable estrogen and mild increase in cortisol, withoutinflammation and itching. Alaskan Malamute, Chow-Cow, Keeshond, Norwegian Elkhound,Pomeranian and Samoyed breeds show more susceptibility and susceptibility to the disease.Clinical findings may occur as psychogenic as well as dermatological findings. Alopecia in areasother than head and distal extremities, bilateral symmetrical alopecia, hyperpigmentation, and post traumatic hair regrowth are important clinical findings. Anamnesis, biochemical parameters anddermatohistopathological findings are basics for diagnosis. In the differential diagnosis,hyperadrenocorticism, hypothyroidism and congenital alopecia should be considered. Thetreatment includes castration, melatonin, mitotane and trilostane applications. In recent years,microneedling method used in human medicine and cosmetics industry is important. In conclusion,it is noteworthy that more effective diagnostic approaches are needed in order to develop treatmentoptions that can be applied according to the course of the disease.

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