Konjenital İntestinal Atrezili Buzağılarda Bazı Hematolojik Parametreler ile Serum Kardiyak Belirteçlerin Düzeyinin Araştırılması

Ruminantlarda görülen konjenital anomaliler dünyadaki çeşitli araştırmacılar tarafından yaygınolarak bildirilmektedir. İntestinal atrezi, buzağılarda bağırsağın çeşitli bölümlerinin tıkanıklığı olaraktanımlanır. İntestinal atrezi anüs ve/veya rektum, jejenum, kolon ve ileumda görülebilir. Atrezia anive atrezia koli, intestinal atrezinin en sık görülen şeklidir. Bu çalışmada intestinal atrezi vakalarınınkardiyak belirteçlerinin ve hematolojik parametrelerinin sağlıklı buzağılar ile oluşturulan gruba göredeğerlendirilmesi amaçlandı. Çalışmada kliniğimize getirilen 36 adet intestinal atrezili buzağınınhematolojik ve biyokimyasal parametreleri değerlendirildi. Hematolojik ve biyokimyasal değerler için1-10 günlük sağlıklı 10 adet buzağı ile kontrol grubu oluşturuldu. Hematolojik muayene veterinerkan sayım cihazı ile yapıldı. Elde edilen serumlarda kardiyak troponin I (cTn-I), myokard kökenlikreatin kinaz (CK-MB) ve myoglobin değerleri ticari test kitleri kullanılarak ölçüldü.İntestinal atrezili buzağıların ortalama trombosit hacmi (MPV), trombosit dağılım genişliği (PDWc),nötrofil (NEU), nötrofil yüzdesi (NEU%) değerlerinde kontrol grubuna göre istatistiksel açıdananlamlı bir artış gözlenirken lenfosit yüzdesi (LY%) değerinde istatistiksel açıdan anlamlı bir azalmasöz konusudur. İntestinal atrezili buzağılarda lökosit (WBC), cTn-I ve CK-MB düzeylerindeistatistiksel olarak anlamlı olmayan bir artış gözlenmiştir.Sonuç olarak, intestinal atrezili buzağılarda sağlıklı gruba göre hematolojik ve kardiyakparametrelerde istatistiksel olarak anlamlı değişiklikler gözlenmiştir. İntestinal atrezili buzağılardahematolojik ve kardiyak parametrelerin birlikte değerlendirilmesinin bu hastalarda prognostik önemtaşıyabileceği kanısına varıldı.

Investigation of levels of some cardiac biomarkers and serum haematological parameters in calves with congenital intestinal atresia

Congenital anomalies in ruminants are widely reported by various researchers around the world. Intestinal atresia is defined as the atresia of various segments of intestine in calves. Intestinal atresia can be seen in anus and/or rectum, jejunum, colon, and ileum. Atresia ani and atresia coli are most commonly seen form of atresia. In the present study, it was aimed to compare the cardiac indicators and hematological parameters of calves with intestinal atresia to those of healthy calves The study cases were 36 calves accepted to our clinic evaluated for hematology and biochemistry results of intestinal atresias. Hematological and biochemical analyzes of 10 healthy calves at 1-10 days old were performed as a control group. Haematological examinations were made by veterinary blood counter. Cardiac troponin I (cTn-I), myocardial creatin kinase (CK- MB) and myoglobin levels were determined by commercial kits as using in the obtained serum samples. Hematologic and biochemical parameters and statistical differences of healthy and intestinal atresi calves were presented. mean platelet volume (MPV), platelet distribution width (PDWc), neutrophil (NEU), percentage of neutrophils (NEU%) values was significantly higher compared the control group, but percentage of leucosyte (LY%) value was significantly lower compared to control group. There is a statistically insignificant increase in white blood cells (WBC), cTn-I and CK-MB levels in calves with intestinal atresia. In conclusion, changes were observed in hematological and cardiac parameters in calves with atresia coli. Also, according to results of this study, it was concluded that co-evaluation of hematologic and cardiac parameters was found to be crucial for prognosis in intestinal atresias.

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