Evcil Hayvanların Kronik Yaralarında Debridement Yöntemleri
Hayvanlarda iyileşmesi uzun zaman alan kronik yaraların tedavileri önemli bir sorun olmaya devametmektedir. Kronik yaralar genel olarak diyabetik yaralar, dekubital yaralar, yanık yaraları venöziskemikülserler ve arteriyel yetmezlik yaraları olarak sınıflandırılmaktadır. Kronik yaralarda anatedavi cerrahi müdahaledir. Debridement bu amaçla uygulanan yöntemlerden birisidir.Debridement; cerrahi, mekanik, otolitik, enzimatik ve biyolojik debridement olarakbölümlendirilmektedir. Yara bölgesindeki nekrotik dokuların ve metabolik artıkların bölgedeki canlıdokular gözleninceye kadar bölgeden uzaklaştırılması işlemi olarak tanımlanan debridement ileyara iyileşmesinin hızlandırılması amaçlanmaktadır. Bu derlemede evcil hayvanlarda oluşabilecekkronik yaralar ve tedavileri ile ilgili son gelişmeler hakkında bilgiler verildi. Cerrahi, mekanik, otolitik,enzimatik ve biyolojik debridement yöntemleri ile bu yöntemlerin avantaj ve dezavantajları hakkındabilgi verilerek bu konuda yapılan çalışmaların sonuçları değerlendirildi.
Debridement Methods in Chronic Wounds of Domestic Animals
Treatment of chronic wounds which take a long time to heal remains an important problem in animals. Generally, chronic wounds are studied as diabetic wounds, pressure wounds, burn wounds, venous-ischemic ulcers and arterial insufficiency wounds. The main treatment in chronic wounds is surgical intervention. Debridement is one of the methods applied for this purpose. Debridement is classified as surgical, mechanical, autolytic, enzymatic and biological debridement. It is aimed to accelerate wound healing by debridement, which is defined as the removal of necrotic tissues and the removal of metabolic debris from the wound area until living tissue in the region is observed. In this review, information on recent developments related to chronic wounds and their treatments in domestic animals have provided. Surgical, mechanical, autolytic, enzymatic and biological debridement methods and advantages and disadvantages of these methods have been given and the results of these studies have been evaluated.
___
- Han MC, Durmuş AS, Sağlıyan A, et al. Effects of Nigella
sativa and Hypericum perforatum on wound healing. Turk
J Vet Anim Sci 2017; 41: 99-105.
- Olczyk P, Mencner L, Komosinska-Vassev K. The role of
the extracellular matrix components in cutaneous wound
healing. Biomed Res Int 2014; 2014: 1-8.
- Velnar T, Bailey T, Smrkolj V. The wound healing process:
An overview of the cellular and molecular mechanisms. J
Int Med Res 2009; 37: 1528-1542.
- Diegelmann RF, Evans MC. Wound healing: An overview
of acute, fibrotic and delayed healing. Front Biosci 2004; 9:
283-289.
- Durgun T, Durmuş AS, Kaplan M. Klinik ve deneysel
çalışmalarda lokal diphenylhydantoin’in yara iyileşmesi
üzerine etkisi. FÜ Sağlık Bilimleri Dergisi 1999; 13: 151-
157.
- Erkuş B, “Kronik Yara Çeşitleri”. http://www.
acibademhemsirelik.com/e-dergi/yeni_tasarim/files/
KRONİK%20YARA%20ÇEŞİTLERİson.pdf/ 11.11.2017.
- Yapucu Güneş Ü. Kronik yaraların değerlendirilmesi. CÜ
Hemşirelik Yüksekokulu Dergisi 2007; 11: 38-44.
- Uccioli L, İzzo V, Meloni M, et al. Non-healing foot ulcers in
diabetic patients: General and local interfering conditions
and management options with advanced wound dressings.
J Wound Care 2015; 24: 35-42.
- Aktaş Ş. Kronik yarada lokal faktörler ve yardımcı
tedaviler. ANKEM Derg 2012; 26: 217-222.
- Hong WX, Hu MS, Esquivel M, et al. The role of hypoxiainducible
factor in wound healing. Adv Wound Care 2014;
3: 390-399.
- Osman AH, Kamel MM, Wahdan MH, Al-gazaly Mahmoud.
Assesment to the effects of low power diode laser on
wound healing in diabetic rats. Life Sci J 2013; 10: 1313-
1321.
- Görgül OS, Yavru N, Atalan G, ve ark. Veteriner Özel
Cerrahi. Malatya: Medipres Yayınları, 2012.
- Topsakal Ş, Özmen Ö. İnsan ve hayvanlarda diabetes
mellitus. MAE Vet Fak Derg 2016; 1: 47-57.
- Jude EB, Apelqvist J, Spraul M, Martini J. Prospective
randomized controlled study of Hydrofiber dressing
containing ionic silver or calcium alginate dressings in nonischaemic
diabetic foot ulcers. Diabet Med 2007; 24: 280-
288.
- Reddy GK, Stehno-Bittel L, Enwemeka CS. Laser
photostimulation accelerates wound healing in diabetic
rats. Wound Repair Regen 2001; 9: 248-255.
- Nteleki B, Houreld NN. The use of phototherapy in the
treatment of diabetic ulcers. JEMDSA 2012; 17: 128-132.
- Hofman D. The autolytic debridement of venous leg ulcers.
Wound Essentials 2007; 2: 68-73.
- Durmus AS, Yaman M, Can HN. Effects of extractum
cepae, heparin, allantoin gel and silver sulfadiazine on
burn wound healing: An experimental study in a rat model.
Veterinarni Medicina 2012; 57: 287-292.
- Han MC, Durmuş AS, Karabulut E, Yaman İ. Effects of
Turkish propolis and silver sulfadiazine on burn wound
healing in rats. Revue Med Vet 2005; 156: 624-627.
- Yaman İ, Durmuş AS, Çeribaşı S, Yaman M. Effects of
Nigella sativa and silver sulfadiazine on burn wound
healing in rats. Veterinarni Medicina 2010; 55: 619-624.
- Kurtoğlu AH, Karataş A. Yara tedavisinde güncel
yaklaşımlar: Modern yara örtüleri. Ankara Ecz Fak Derg
2009; 38: 211-232.
- Steed DL. Debridement. Am J Surg 2004; 187: 71S-74S.
- Falabella AF. Debridement and wound bed preparation.
Dermatol Ther 2006; 19: 317-325.
- Taşdemir N, Yavuz M. Yara bakımında debridman
yöntemleri. Maltepe Üniversitesi Hemşirelik Bilim ve Sanat
Dergisi 2008; 1: 69-75.
- Elraiyah T, Domecq JP, Prutsky G, et al. A systematic
review and meta-analysis of debridement methods for
chronic diabetic foot ulcers. J Vasc Surg 2016; 63: 37S45S.
- Nisbet HÖ. Yara sağaltımında konservatif yöntemler.
Türkiye Klinikleri J Vet Sci Surg-Special Topics 2016; 2:
16-24.
- Smith F, Dryburgh N, Donaldson J, Mitchell M.
Debridement for surgical wounds. Cochrane Database
Syst Rev 2013; 9: 1-38.
- Gordon KA, Lebrun EA, Tomic-Canic M, Kirsner RS. The
role of surgical debridement in healing of diabetic foot
ulcers. Skinmed 2012; 10: 24-26.
- Sorensen JL, Jorgensen B, Gottrup F. Surgical treatment
of pressure ulcers. Am J Surg 2004; 188: 42S-51S.
- Gurunluoglu R. Experiences with waterjet hydrosurgery
system in wound debridement. World J Emerg Surg 2007;
2: 10.
- Kawecki M, Mikuś-Zagórska K, Glik J, Nowak M. The
efficiency of burn wounds debridement with use of
hydrosurgery - our experience. Pol Przegl Chir 2015; 87:
1-5.
- Rennekampff HO, Schaller HE, Wisser D, Tenenhaus M.
Debridement of burn wounds with a water jet surgical tool.
Burns 2006; 32: 64-69.
- Demir A, Demirtaş Y, Çifçi M, Öztürk N, Karacalar A.
Topikal negatif basınç (vakum yardımlı kapama [VAC])
uygulamalarımız. Türk Plast Rekonstr Est Cer Derg 2006;
14: 171-177.
- Durmuş AS, Han MC, Yaman İ. Comperative evaluation of
collagenase and silver sulfadiazine on burned wound
healing in rats. FÜ Sağ Bil Vet Derg 2009; 23: 135-139.
- Hamilton L, Kožár M. Efficiency of enzymatic debridement
in the healing process of chronic wounds in small animal
practice. Folia Vet 2017; 61: 38-42.
- Choudhary V, Choudhary M, Pandey S, Chauhan VD,
Hasnani JJ. Maggot debridement therapy as primary tool
to treat chronic wound of animals. Veterinary World 2016;
9: 403-409.
- Chan DC, Fong DH, Leung JY, Patil NG, Leung GK.
Maggot debridement therapy in chronic wound care. Hong
Kong Med J 2007;13: 382-386.
- Parnés A, Lagan KM. Larval therapy in wound
management: A review. Int J Clin Pract 2007; 61: 488-493.
- Kocisova A, Pistl J, Link R, Conkova E, Goldova M.
Maggot debridement therapy in the treatment of footrot
and foot scald in sheep. Acta Vet Brno 2006; 75: 277-281.
- Mumcuoğlu KY, Taylan Özkan A. Supuratif kronik
yaraların maggot debrideman tedavisi. Türkiye Parazitol
Derg 2009; 33: 307-315.
- Tanyüksel M, Koru Ö, Araz RE, et al. Kronik yaraların
tedavisinde steril Lucilia sericata larva uygulamaları.
Gülhane Tıp Derg 2014; 56: 218-222.
- Yağız S, Baltacı Göktaş S. Bası yarasında maggot
debridman tedavisi: Olgu sunumu. IAAOJ Health Science
2015; 3: 21-29.
- Yıldız Ş, Tanyüksel M, Araz E, et al. Biological
debridement with maggots in chronic wounds: A case
series. TAF Prev Med Bull 2016; 15: 336-341.
- Gunjegaonkar SM, Kshirsagar SS. Bayas JP. Bio-surgical
therapy- overview. IJPR 2016; 6: 133-137.
- Sherman RA. Maggot versus conservative debridement
therapy for the treatment of pressure ulcers. Wound
Repair Regen 2002; 10: 208-214.
- Burba D. Traumatic foot injuries in horses: Surgical
management. Compend Contin Educ Vet 2013; 35: E5.
- Polat E, Çakan H, İpek T. Larva debridman tedavisi (LDT).
Türk Aile Hek Derg 2010; 14: 188-191.
- Bras RJ, Morrison S. Retrospective case series of 20
horses (2002–2009) sustaining puncture wounds to the
navicular bursa with maggot debridement therapy as an
adjunctive treatment. Proceedings of the Annual
Convention of the American Association Equine
Practitioners. Las Vegas (NV): AAEP 2009; 55: 241-250.
- Sherman RA, Stevens H, David NG, Iversen E. Treating
wounds in small animals with maggot debridement
therapy: A survey of practitioners. Vet J 2007; 173: 138-
143.
- Lepage OM, Doumbia A, Perron-Lepage MF, Gangl M.
The use of maggot debridement therapy in 41 equids.
Equine Vet J 2012; 44: 120-125.
- Sherman RA, Morrison S, David NG. Maggot debridement
therapy for serious horse wounds-A survey of
practitioners. Vet J 2007; 174: 86-91.