Effect of Acarbose on Ruminal Function and Variations of Serum Acute Phase Proteins in Dairy Cows with Subacute Ruminal Acidosis

Bu çalışmada, subakut rumen asidozlu (SARA) süt ineklerinin rasyonuna tedavi amaçlı ilave edilen akarbozun, rumenin fermentasyon özellikleri ve akut faz proteinlerinin (APP) düzeylerine olan etkileri araştırılmıştır. Çalışmada her birinde 6 hayvan olmak üzere, 4 grupta toplam 24 SARA pozitif Holstein inek kullanılmıştır. Tedavi olarak 1) 1 mg akarboz / kg CA, 2) 2 mg akarboz / kg CA, 3) 3 mg akarboz / kg CA ve 4) kontrol (herhangi bir katkı maddesi yok) kullanılmıştır. Rumen sıvısı örnekleri, sabah yemlemesi sonrasından 12 saate kadar 4er saatlik aralıklarla alınmıştır. Kontrol grubu ile karşılaştırıldığında, akarbozun yemlemeden sonra tüm gruplarda rumen pH değerini arttırdığı görülmüştür (P

Subakut Ruminal Asidoz Teşhis Edilen Süt İneklerinde Serum Akut Faz Proteinlerdeki Değişiklikler ve Akarbozun Ruminal Fonksiyon Üzerine Olan Etkisi

The aim of this study was to investigate the effects of acarbose addition to the ration of dairy cows on changes in ruminal fermentation characteristics and variations of acute phase proteins (APPs) in dairy cows with subacute ruminal acidosis (SARA). A total of 24 SARA positive Holstein cows that were divided into 4 groups containin 6 cows in each were used in the study. Treatments were 1) 1 mg of acarbose/kg of BW, 2) 2 mg of acarbose/kg of BW, 3) 3 mg of acarbose/kg of BW and 4) control, no additive. Rumen fluid samples were taken starting from immediately after morning feding and at 4-h intervals until 12 h period. Acarbose increased ruminal pH in all groups immediately after feeding compared to control group (P

___

  • 1. Gumus H. Akarbozun asidozis üzerine etkisi. MAKÜ Sag Bil Enst Derg 2014; 2: 42-49. 2. Owens FN, Secrist DS, Hill WJ, Gill DR. Monensin and abomasal protein passage of steers. J Anim Sci 1998; 76, 275-282. 3. Nocek JE. Bovine acidosis: Implications on laminitis. J Dairy Sci 1997; 80: 1005-1028. 4.McLaughlin CL, Thompson A, Greenwood K, Sherington J, Bruce C. Effect of acarbose on acute acidosis. J Dairy Sci 2009; 92: 2758-2766. 5. Kleen JL, Hooijer GA, Rehage J, Noordhuizen JPTM. Subacute Ruminal Acidosis (SARA): A Review. J Vet Med A 2003; 50: 406-414. 6. Nordlund KV, Garrett EF, Oetzel GR. Herd-based rumenocentesis: A clinical approach to the diagnosis of subacute rumen acidosis. Compend Contin Educ Pract Vet 1995; 17: 48-56. 7.Owens F, Secrist D, Hill J, Gill D. A new look at acidosis. Conf Proc Southwest Nutr Mgmt Conf Phoenix, AZ, 1996: 1-16. 8. Garry FB. Indigestion in ruminants. In: Smith BP. (Editor). Large Animal Internal Medicine, 3rd Edition, St Louis, Baltimore: Mosby, 2002: 722-747. 9. Keunen JE, Plaizier JC, Kyriazakis L, et al. Effects of a subacute ruminal acidosis model on the diet selection of dairy cows. J Dairy Sci 2002; 85: 3304-3313. 10. Russell JB, Allen MS. Physiological basis for interactions among rumen bacteria using Streptococcus bovis and Megasphaera elsdenii as a model in Current Perspectives in Microbial Ecology. Washington, DC: American Society for Microbiology, 1984: 239-247. 11. Plaizier JC, Krause DO, Gozho GN, McBride BW. Subacute ruminal acidosis in dairy cows: The physiological causes, incidence and consequences. Vet J 2008; 176: 21- 31. 12. Yu-Yang Y, Yu-Jie L, Wei-Yun Z, Sheng-Yong MB. Effects of Acarbose addition on ruminal bacterial microbiota, lipopolysaccharide levels and fermentation characteristics in vitro. Asian Australas. J Anim Sci 2014; 27: 1726-1735. 13. Cannizzo C, Gianesella M, Giudice E, et al. Serum acute phase proteins in cows with SARA (Subacute Ruminal Acidosis) suspect. Arq Bras Med Vet Zootec 2012; 64: 15- 22. 14. Enemark JMD, Jorgensen RJ, Enemark P. Rumen acidosis with special emphasis on diagnostic aspects of subclinical Rumen acidosis: A review. Veterinarijair ir Zootechnika 2002; 20: 16-29. 15. Enemark JMD. The monitoring prevention and treatment of subacute ruminal acidosis (SARA): A review. Vet J 2008; 176: 32-43. 16. Mohebbi M, Sajedianfard J, Nazifi S, Samimi AS. Changes of serum amyloid A, haptoglobin, ceruloplasmin, fibrinogen, and lipid-associated sialic acid in sheep fed high grain rations with altered digestive functions. Comp Clin Pathol 2010; 19: 541-546. 17.Edmonson AJ, Lean IJ, Weaver LD, Farver T, Webster G. A body condition scoring chart for Holstein Dairy Cows. J Dairy Sci 1989; 72: 68-78. 18. AOAC. Official Methods of Analysis of AOAC International, 16th Edition, Washington, DC: Association of Official Analytical Chemists, 1997. 19.Van Soest PJ. Development of a Comprehensive system of feed analyses and its application to forages. J Anim Sci 1967; 26: 119-128. 20. Ding X, Long R, Dan R, Jiao T, Zhang X. A determination method based on gas chromatography for analysis of volatile fatty acids in rumen fluid. J Gansu Agric University 2006; 41: 24-26. 21. Petit HV, Flipot PM. Source and feeding of nitrogen on growth and carcass characteristics of beef steers fed grass as hay or silage. J Anim Sci 1992; 3: 867-875. 22. Nagaraja TG, Avery TB, Gilitzert SJ, Holman DL. Effect of ionophore antibiotics on experimentally induced lactic acidosis in cattle. Am J Vet Res 1985; 46: 2444-2452. 23. Reynolds CK. Production and metabolic effects of site of starch digestion in dairy cattle. Anim Feed Sci Technol 2006; 130: 78-94. 24. Baumann H, Gauldie J. The acute phase response. Immunology Today 1994; 15: 74-80. 25. Gozho GN, Plaizier JC, Krause DO, Kennedy AD, Wittenberg KM. Subacute ruminal acidosis induces ruminal lipopolysaccharide release and triggers an inflammatory response. J Dairy Sci 2005; 88: 1399-1403. 26. Gozho GN, Krause DO, Plaizier JC. Effects of gradual adaptation to concentrate and subsequent induction of subacute ruminal acidosis in steers on ruminal lipopolysaccharide and acute phase proteins. J Dairy Sci 2006; 89: 4404-4413. 27. Gozho GN, Krause DO, Plaizier JC. Ruminal lipopolysaccharide concentration and inflammatory response during grain induced subacute ruminal acidosis in dairy cows. J Dairy Sci 2007; 90: 856-866. 28. Khafipoor E, Krause DO, Plaizier JC. Influence of grain induced sub-acute ruminal acidosis (SARA on lipopolysaccharide endotoxin (LPS) and acute phase proteins. Canadian J Anim Sci 2006; 86: 577.
Fırat Üniversitesi Sağlık Bilimleri Veteriner Dergisi-Cover
  • ISSN: 1308-9323
  • Yayın Aralığı: Yılda 3 Sayı
  • Yayıncı: Prof.Dr. Mesut AKSAKAL
Sayıdaki Diğer Makaleler

Anestezi Sırası ve Sonrasında Görülen Kaza ve Komplikasyonlar ve Bunların Sağaltımları

Sami ÜNSALDI

Aksaray Malaklı Köpeği ile Kangal Köpeği Neurocranium ve Splanchnocranium Kemiklerinin Bazı Osteometrik Ölçümlerinin Karşılaştırılmalı Olarak İncelenmesi

Ramazan İLGÜN, Zait Ender ÖZKAN

Yün Yeme Hastalığı Olan Koyunlarda Bazı İz Elementler ve Serum Biyokimyası

Ersoy BAYDAR, Mehtap ÖZÇELİK, Abdulllah GAZİOĞLU

Tavukçuluk Atıklarından Biyogaz Üretimi

Fatma YENİLMEZ

Kayseri'deki Köpeklerde Canine Adenovirus Seroprevalansı

Kezban ŞAHNA CAN, Öznur ASLAN

Yaban Domuzlarında (Sus scrofa) Neurocranium'u Oluşturan Kemiklerin Makro-Anatomik Olarak İncelenmesi

Sadık YILMAZ, Meryem KARAN

Effects of Use of Lactic Acid Bacteria Isolated from Whole Crop Corn as Inoculant on Corn Silage Fermentation and Aerobic Stability

Ökkeş YILMAZ, Mehmet Ali AZMAN, Seda MUTLU İFLAZOĞLU, Fatma TERLEMEZ, Mehmet YILMAZ

Elazığ İlinde Koyunlarda Mera Öncesi, Mera Dönemi ve Mera Sonrası Kan Serumlarında Bazı Mineral Madde Düzeylerinin Tespiti

Mehmet ÇİFTÇİ, Mehtap ÖZÇELİK, Osman GÜLER, Uğur ORAK, Bayram KABADAYI

Effect of Injection of Vitamin E and Selenium Administered Immediately Before the Ovsynch Synchronization on Conception Rate, Antioxidant Activity and Progesterone Levels in Dairy Cows

Atilla YILDIZ, Engin BALIKÇI, Fuat GÜRDOĞAN

Bir Köpekte Kondrosarkom Olgusu

Burak KARABULUt, Murat TANRISEVER, Hatice ERÖKSÜZ, İbrahim CANPOLAT