Dev Kondiloma Aküminata Olgusunun Cerrahi Eksizyon ile Tedavisi

Dev kondiloma aküminata, Buschke-Löwenstein Tümörü olarak bilinen, seksüel yolla bulaşan ve ano-genital bölgede görülen bir cilt lezyondur. Dev kondiloma aküminata, ağrısız, karnıbahar görünümünde ve basit kondilomanın aksine, lokal agresiv ve destrüktiftir. Histolojik olarak bening görünmesine rağmen, malign karakterde davranabilmektedir. Bu raporda, 55 yaşında evli bir erkek hastada penis, skrotum, perineum ve inguinal bölgeyi kaplayan dev kondiloma aküminata olgusu sunulmuştur. Geniş ve agresif cerrahi eksizyon yapılarak oluşan defekt kısmi kalınlıktaki deri grefti ile onarılmıştır. Postoperatif dönemde tamamen iyileşen hastada yapılan 4 yıllık takibinde nüks görülmemiştir.

Treatment of A Giant Condyloma Acuminatum by Surgical Excision

Giant condyloma acuminatum, also known as Buschke-Löwenstein tumor that occurs in ano-genital region and transmitted by sexual way. Giant condyloma acuminatum is an indolent cauliflower-like tumor, but unlike simple condyloma, it is locally aggressive and destructive. In spite of its histologically benign appearance, it may behave malignantly. We present in this report a 55 years old married male with giant condyloma located at the involving penis, scrotum, perineum, and inguinal region. An extensive and aggressive surgical excision was performed. The entire wound was repaired with a split thickness graft. He was healthy without any evidence of tumor at the end of four postoperative years.

PDF

___

1. Buschke A, Lowenstein L. Uber carcinomahnliche condylomata acuminata des penis. Klin Wochenschr 1925; 4: 1726-28.
2. Papiu HS, Dumnici A, Olariu T, et al. Perianal giant condyloma acuminatum (Buschke-Löwenstein tumor). Case report and review of the literature. Chirurgia (Bucur) 2011; 106: 535-39.
3. Yaman I, Bozdag AD, Derici H, Tansug T, Reyhan E. Verrucous carcinoma arising in a giant condyloma acuminata (Buschkelowenstein Tumour): ten-year follow-up. Ann Acad Med Singapore 2011; 40: 104-5.
4. Hicheri J, Jaber K, Dhaoui MR, Youssef S, Bouziani A, Doss N. Giant condyloma (Buschke-Löwenstein tumor). A case report. Acta Dermatovenerol Alp Panonica Adriat 2006; 15: 181-83.
5. Renzi A, Giordano P, Renzi G, Landolfi V, Del Genio A, Weiss EG. Buschke-Lowenstein tumor successful treatment by surgical excision alone: a case report. Surg Innov 2006; 13: 69-72.
6. Gholam P, Enk A, Hartschuh W. Successful surgical management of giant condyloma acuminatum (Buschke-Löwenstein tumor) in the genitoanal region: a case report and evaluation of current therapies. Dermatology 2009; 218: 56-59.
7. Türkdogan P, Bastürk O, Demir MA, Zeytinoglu A, Seyhan A. Giant condyloma acuminatum - two cases with microinvasive foci in one. J Aegean Pathology 2004; 1: 62-65.
8. Gross G, Pfister H. Role of human papillomavirus in penile cancer, penile intraepithelial squamous cell neoplasias and in genital warts. Med Microbiol Immunol 2004; 193: 35-44.
9. Bogomoletz WV, Potet F, Molas G. Condylomata acuminata, giant condyloma acuminatum (Buschke-Loewenstein tumour) and verrucous squamous carcinoma of the perianal and anorectal region: a continuous precancerous spectrum? Histopathology 1985; 9: 1155-69.
10. Chu QD, Vezeridis MP, Libbey NP, Wanebo HJ. Giant condyloma acuminatum (Buschke-Lowenstein tumor) of the anorectal and perianal regions. Analysis of 42 cases. Dis Colon Rectum 1994; 37: 950-57.