Murat Sırrı AKOSMAN, Aysun ÇEVİK DEMİRKAN, Esra BAŞARAN

Volumetric analysis of the total and subcomponents of the chinchilla kidneys

Amaç: Böbreklerin ve alt bileşen hacimlerinin bilinmesi tedavide ya da gerçekleştirilecek olan çalışmalarda göz önünde bulundurulması gereken kritik önemi olan bölgelerdir. Sunulan bu çalışma beş adet erkek ve beş adet dişi yetişkin şinşillanın sağ ve sol böbrekleri üzerinde gerçekleştirilmiş olup böbreklerin total ve alt bileşenlerinin hacimlerinin hesaplanması amaçlanmıştır.Gereç ve Yöntem: Çalışmada beş adet dişi ve beş adet erkek yetişkin şinşillanın sağ ve sol böbreklerinin toplam ve alt bileşenlerinin hacimleri hesaplandı. Arşimet prensibi sadece toplam hacim ölçümünde kullanılırken Cavalieri metodu böbreklerin hem toplam hem de alt bileşenlerinin hacim hesaplanmasında kullanıldı.Bulgular: Analizler sonucunda ortalama böbrek hacimleri Arşimet prensibine göre erkekler için 1.11 cm³ iken dişiler için 0.94 cm³ olarak bulundu. Cavalieri metoduna göreyse bu değer erkekler için 0.97 cm³ iken dişiler içinse 0.84 cm³ olarak hesaplandı. Korteks, medulla ve pelvisin yüzde oranları da erkekler için %71, %26, %3 ve dişiler içinde %71, %27, %2 olarak bulundu. Metotlar ve cinsler arasında, cinsler içinde ve böbrekler arasında istatistiksel olarak karşılaştırma yapıldığında herhangi bir önem (p>0.05) bulunamadı.Öneri: Böbreğin toplam hacmi hem Arşimet prensibi hem de Cavalieri metoduyla ölçülebilir. Ancak böbreğin alt bileşenleri sadece Cavalieri metoduyla hesaplanabilir. Sunulan bu çalışmada şinşilla böbreğinin toplam ve alt bileşenlerinin hacimleri morfolojik olarak ortaya konmuştur. Böbrek üzerinde yapılacak olan deneysel çalışmalarda bu bölgelerin hacimlerinin ölçülmesi çalışmaya katkı sağlayacaktır.

Şinşilla böbreğinin total ve alt bileşenlerinin hacim analizi

Aim: It is critically important to know the volume of the kidneys, which are vital for the body, in order to use the volume data for the treatment or to contribute to other studies. Thus present study aimed to estimate the total and subcomponent volume of the kidney in the chinchilla.Materials and Methods: The present study was estimated the total and subcomponents volume of left and right kidneys of five male and five female adult chinchillas. The kidneys' total volume was measured by both Archimedean Principle and Cavalieri method while the volumes of the subcomponents were estimated by Cavalieri method. All estimated parameters were compared by statistically.Results: The mean volume of the kidneys' was estimated as 1.11 cm³ for males and 0.94 cm³ for females by Archimedean principle. However it was 0.97 cm³ for males and 0.84 cm³ for females by Cavalieri method. The volume fractions of the kidney cortex, medulla and pelvis were 71%, 26%, 3% for the male and 71%, 27%, 2% for the female, respectively. Moreover all parameters such as weight, volume and volume fractions were statistically evaluated and no significant difference (p>0.05) was observed between the right and left kidneys and between the genders.Conclusion: The total volume of the kidney could be estimated by both Archimadean principle and Cavalieri method. However, the volume of the subcomponents in the kidney could only be estimated by Cavalieri method. Actually, total and subcomponent volume estimations of the kidney will contribute the findings of the experimental studies. It was concluded that this stereological study could provide a valuable contribution to future studies performed on kidney.

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