Alireza SAZMAND, Javad TAJIK, Seyed Hossein HEKMATİMOGHADDAM, Mohamad Reza SHIRAZI

Evaluation of serum concentration of cardiac troponin I in normal racing thoroughbred horses

Amaç: Safkan yarış atlarında serum kardiyak troponin I düzeylerini belirlemektir.Gereç ve Yöntem: Klinik olarak sağlıklı 49 adet safkan yarış atından elde edilen serumlardan troponin I düzeyi ticari olarak satılan ELISA kiti ile belirlendi.Bulgular: Serum troponin I düzeyi ortalaması 0.504±0.083 ng/mL (

Safkan yarış atlarında serum kardiyak troponin I düzeylerinin değerlendirilmesi

Aim: Evaluation of serum concentration of cardiac troponin I in racing thoroughbred horses.Materials and Methods: Serum concentration of troponin I was measured in 49 clinically healthy thoroughbred horses using commercial ELISA detection kits.Results: The mean serum concentrations of troponin I was 0.504±0.083 ng/mL (

PDF

___

Adams JE, Bodor GS, Davila-Roman VG, Delmez JA, Apple FS, Ladenson JH, Jaffe AS, 1993. Cardiac troponin IA marker with high specificity for cardiac injury. Circulation, 88, 101-106.
Adin DB, Milner RJ, Berger KD, Engel C, Salute M, 2005. Cardiac troponin I concentrations in normal dogs and cats using a bedside analyzer. J Vet Cardiol, 7, 27-32.
Basbugan Y, Agaoglu A, Yuksek N, 2010. An investigation on serum troponin concentration in healthy ruminants. Kafkas Univ Vet Fak Derg, 16, 641-645.
Begg LM, Hoffmann KL, Begg AP, 2006. Serum and plasma cardiac troponin I concentrations in clinically normal Thoroughbreds in training in Australia. Aust Vet J, 84, 336-337
Buczinski S, Belanger AM, 2010. Bovine tricuspid endocarditis as a cause of increased serum concentration of cardiac troponins. Can Vet J, 51, 195
Cornelisse CJ, Schott HC, Olivier BN, Mullaney TP, Koller A, Wilson DV, Derksen FJ, 2000. Concentration of cardiac troponin I in a horse with a ruptured aortic regurgitation jet lesion and ventricular tachycardia. J Am Vet Med Assoc, 217, 231-235.
Hekmatimoghaddam S, Sazmand A, Tajik J, Shirazi M, 2011. Serum cardiac troponin I concentrations in the camel and buffalo. Online J Vet Res, 15, 514-519.
Karapinar T, Dabak DO, Kuloglu T, Bulut H, 2010. High cardiac troponin I plasma concentration in a calf with myocarditis. Can Vet J, 51, 397-399.
Kraus MS, Jesty SA, Gelzer AR, Ducharme NG, Mohammed HO, Mitchell LM, Soderholm LV, Divers TJ, 2011. Measurement of plasma cardiac troponin I concentration by use of a point-of-care analyzer in clinically normal horses and horses with experimentally induced cardiac disease. Am J Vet Res, 71, 55-59.
Lucia P, Coppola A, Manetti LL, Sebastiani ML, Colliardo A, Cerroni F, De Martinis C, Strappini PM, 2001. Cardiac troponin I in acute coronary ischemic syndromes. Epidemiological and clinical correlates. Int J Cardiol, 77, 215-222.
Nath LC, Anderson GA, Hinchcliff KW, Savage CJ, 2012. Serum cardiac troponin I concentrations in horses with cardiac disease. Australian Vet J, 90, 351-357.
Nostell K, Brojer J, Hoglund K, Ender A and Haggstrom J, 2012. Cardiac troponin I and the occurrence of cardiac arrhythmias in horses with experimentally induced endotoxaemia. Vet J, 192, 171-175.
Nostell K, Haggstrom J, 2008. Resting concentrations of cardiac troponin I in fit horses and effect of racing. J Vet Cardiol, 10, 105-109.
O'Brien PJ, 2008. Cardiac Troponin is the most effective translational safety biomarker for myocardial injury in cardiotoxicity. Toxicol, 245, 206-218.
OBrien PJ, Smith DEC, Knechtel TJ, Marchak MA, Pruimboom Brees I, Brees DJ, Spratt DP, Archer FJ, Butler P, Potter AN, Provost JP, Richard J, Snyder PA, Reagan WJ, 2006. Cardiac troponin I is a sensitive, specific biomarker of cardiac injury in laboratory animals. Laborat Anim, 40, 153-171.
Peek SF, Apple FS, Murakami MA, Crump PM, Semrad SD, 2008. Cardiac isoenzymes in healthy Holstein calves and calves with experimentally induced endotoxemia. Can J Vet Res, 72, 356-361
Phillips W, Giguere S, Franklin RP, Hernandez J, Adin D, Peloso J G, 2003. Cardiac Troponin I in pastured and race-training Thoroughbred horses. J Vet Intern Med, 17, 597-599.
Radostis OM, Gay CC, Hichcliff KW, Constable PD, 2007. Veterinary Medicine. 10th edition, WB Saunders Company, Edinburgh, UK, p: 409.
Reef VB, Mc Guirk SM, 2008. Diseases of the cardiovascular system. In: Smith BP, (ed). Large Animal Internal Medicine, 4th edition, St. Louis, Missouri: Elsevier-Saunders, London, UK, pp: 453-489.
Schwarzwald C, Hardy J, Buccellato M, 2003. High cardiac troponin I concentration in a horse with multiforme ventricular tachycardia and myocardial necrosis. J Vet Intern Med, 17, 364-368.
Varga A, Schober KE, Walker WL, Lakritz J, Michael Rings D, 2009a. Correlation of Serum Cardiac Troponin I and Myocardial Damage in Cattle with Monensin Toxicosis. J Vet Intern Med, 23, 1108-1116.
Varga A, Schober KE, Walker WL, Lakritz J, Michael Rings D, 2009b. Validation of a commercially available immunoassay for the measurement of bovine cardiac troponin I. J Vet Intern Med, 23, 359-365.
Varga A, 2008. Use of cardiac troponin for early detection of myocardial damage in dairy cows, M.S. Thesis, OSU College of Veterinary Medicine, Ohio State University, USA, pp: 1-8.