Mahmut OK, Merve İDER, Hasan Hüseyin HADİMLİ

Buzağıların solunum sistemi enfeksiyonunun tedavisinde tilmikosin’in klinik etkinliğinin değerlendirilmesi

Amaç: Bu çalışmanın amacı, buzağıların solunum sistemienfeksiyonunun tedavisinde tilmikosin’in klinik etkinliğinideğerlendirmektir.Gereç ve Yöntem: Bu araştırma solunum sistemi enfeksiyonubulunan 30 buzağı üzerinde gerçekleştirildi. Buzağılardanbronkoalveolar lavaj (BAL) sıvısı örnekleri alındı. Mikrobiyolojikmuayeneleri yapıldı ve etkenlerin antibiyotik duyarlılıklarıbelirlendi. Buzağılara tilmikosin (10 mg/kg) deri altıyolla tek doz uygulandı.Bulgular: Toplam 30 BAL sıvısı örneğinin 11’inde bakteriyelüreme olmazken, 19’unda bakteriyel üreme tespit edildi.Örneklerin 14’ünde Pasteurella multocida (P. multocida),3’ünde Trueperella pyogenes (T. pyogenes) ve 2’sinde Escherichiacoli (E. coli) izole edildi. Bakterilere etkili olan antibiyotiklerinise amoksisilin, sefquinom, marbofloksasin, gamitromisinile tilmikosin olduğu saptandı.Öneri: Sonuç olarak, solunum sistemi enfeksiyonlarında dominantbakterinin Pasteurella multocida olduğu, tilmikosin’inbuzağıların solunum sistemi hastalıklarının tedavisinde etkiliolduğu belirlendi.

Evaluation of clinical efficacy of tilmicosin in the treatment of respiratory system infections of calves

Aim: The aim of this study was to evaluate the clinical efficacy of tilmicosin in the treatment of respiratory system infections of calves. Materials and Methods: This study was performed on 30 calves with respiratory system infections. Bronchoalveolar lavage (BAL) fluid samples were taken from the calves. Microbiological examinations of BAL fluid samples were performed and antibiotic susceptibilities of the agents were determined. A single dose of tilmicosin (10 mg/kg SC) was administered to each calves. Results: While bacterial growth was not observed in 11 of 30 BAL samples, bacterial growth of 19 was detected. Pasteurella multocida (P. multocida) was isolated in 14 of the sample. Remaining bacteria were 3 Trueperella pyogenes (T. pyogenes) and 2 Escherichia coli (E. coli). Amoxicillin, sefquinom, marbofloxacin, gamithromycin and tilmicosin were found to be effective antibiotics. Conclusion: As a result, the dominant bacterium in respiratory system infections is Pasteurella multocida and also tilmicosin was effective in the treatment of respiratory diseases of calves.

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