Erkan AYDIN, ÖMER ŞENORMANCI, Kürşat ALTINBAŞ, Erhan KURT

Ketiapin kötüye kullanımı ve olanzapin ile kombinasyonu sonucu gelişen lökopeni: Bir olgu sunumu

Ketiapin, kötüye kullanım potansiyeli taşıyan atipik bir antipsikotiktir. Olanzapin ise, yapıca ketiapine benzeyen ve literatürde nadiren lökopeniye neden olduğu bildirilmiş bir atipik antipsikotiktir. Burada, yüksek doz ketiapin kötüye kullanımı ve eş zamanlı olanzapin kullanımı sonucu lökopeni gelişen, ketiapinin uzun salınımlı formuna geçiş yapılarak ilaç dozlarının düşürülmesi neticesinde kısa zamanda kan değerleri düzelen bir olgu sunulmuştur.

Leucopenia due to quetiapine abuse and combination with olanzapine: A case report

Quetiapine is an atypical antipsychotic that can be abused. Olanzapine is an another atypical antipsychotic that is similar to quetiapine in chemical structure and cases of leucopenia after olanzapine use have rarely been presented in the literature. In this report, we presented a case of high dose quetiapine abuse and olanzapine combination treatment leading to leucopenia. Blood levels returned to normal levels in a short period of time both by passing to extended release quetiapine and decreasing the daily dosage.

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