Ebru KARAKAYA BİLEN

Köpeklerde Ovariohisterektomi Öncesi ve Sonrası Bazı Hematolojik ve Biyokimyasal Parametrelerin Değerlendirilmesi

Bu çalışma, klinik olarak sağlıklı köpeklerde ovariohisterektominin (OVH) hematolojik ve biyokimyasal parametrelerin rutin ölçümleri üzerine olan etkisini ortaya koymak ve bu parametrelerin sıklıkla yapılan bu ameliyatın herhangi bir komplikasyonunu tanımlamak için kullanıp kullanılamayacağını belirlemek amacıyla yapıldı. Çalışmada gebe olmayan 8 sağlıklı dişi köpek (1-3 yaş) kullanıldı. Kan örnekleri ovariohisterektomi yapılmadan hemen önce ve OVH sonrası 1 ile 7 gün arasında toplandı. Hematolojik parametreler ve aspartat aminotransferaz (AST), alanin aminotransferaz (ALT), kreatin kinaz- miyokard band izoenzimleri (CK-MB), C-reaktif protein (CRP), kolesterol (CHOL), trigliserid (TG), yüksek yoğunluklu lipoproteinler (HDL) ve düşük yoğunluklu lipoproteinler (LDL) seviyeleri belirlendi. Operasyon öncesi ve sonrası istatistiksel farklılıklar, beyaz kan hücresi sayımı (WBC), kırmızı kan hücresi (RBC), AST, CRP ve TG seviyelerinde bulundu. Diğer biyokimyasal parametrelerde anlamlı bir farklılık bulunmadı. Çalışmanın sonuçları, sağlıklı köpeklerin bazı hematolojik ve biyokimyasal parametrelerinin anestezi ve ameliyattan etkilendiğini ortaya koydu.

Evaluation of Some Hematological and Biochemical Parameters Pre- and Post- Ovariohysterectomy in Dogs

The present study was conducted to identify the effect of ovariohysterectomy (OVH) on routine hematological and biochemicalmeasurement variables in clinically healthy dogs and to determine whether these parameters could be used to identify anycomplication of this commonly performed surgery. Non-pregnant 8 healthy female dogs (1-3 years of age) were contained in the study.Blood samples were collected immediately before ovariohysterectomy and between 1 to 7 days throughout after OVH. Hematologicalparameters and levels of aspartate aminotransferase (AST), alanine aminotransferase (ALT), creatine kinase-myocardial bandisoenzymes (CK-MB), C-reactive protein (CRP), cholesterol (CHOL), triglyceride (TG), high-density lipoproteins (HDL), and low-densitylipoproteins (LDL) were determined. The statistical differences were found in the white blood cell count (WBC), red blood cell (RBC),AST, CRP, and TG levels between the pre- and post-operative. There were no significant differences of other biochemical parameters.The results of the study revealed that some hematological and biochemical parameters of healthy dogs are affected by anaesthesia andsurgery.

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