Suat Erol ÇELİK, Yavuz SAMANCI, Sadiye SARATAŞ

Limbus vertebra tanılı kadınlarda kemik mineral yoğunluğu

Amaç: Her ne kadar genetiğin ve kümülatif mekanik stresin immatür bir iskelet sistemi üzerindeki etkilerinin limbus vertebra (LV) gelişiminde rol oynadığı öne sürülse de, LV tanılı hastalarda kemik yapı ile ilgili bir veri yoktur. Bu çalışmanın amacı LV tanısı olan kadınlarda kemik mineral yoğunluğunu (KMY) ve osteoporoz prevalansını değerlendirmek ve yaş ve vücut kitle indeksi (VKİ) eşleştirilmiş sağlıklı kadınlarla karşılaştırmaktı. Yöntem: Bu çalışma LV tanılı 171 kadın (40-49 yaş aralığında) ve LV tanısı olmayan 190 kadın üzerinde yapıldı. Lomber omurga KMY değerleri dual enerji X-ışını absorpsiyometrisi ile elde edildi. Bulgular: Çalışmaya toplam 361 kadın dahil edildi. LV tanılı hastalarda ortalama total KMY değeri istatistiksel olarak anlamlı düşük (sırasıyla 0.876 ± 0.155 ve 0.966 ± 0.187 g / cm2, p

Bone mineral density status in women with limbus vertebra

Objective: Although genetics and cumulative mechanical stress on an immature skeleton have beenproposed to play a role in the development of the limbus vertebra (LV), there is no data concerning the actualdegree of bone strength and bone loss in patients with LV.The aim of this study was to evaluate the bone mineral density (BMD) and the prevalence of osteoporosis inwomen with LV and compare with age- and body mass index-matched women.Method: This study was carried out on 171 women (aged 40–49 years) with LV and 190 women withoutLV. Lumbar spine BMD values were obtained by dual-energy X-ray absorptiometry.Results: A total of 361 patients were included in the study. The mean total BMD value was significantlylower (0.876 ± 0.155 vs. 0.966 ± 0.187 g/cm2, p < 0.0001), and the mean T-score value was significantlyhigher (-1.6 ± 1.41 vs. -0.8 ± 1.71, p < 0.0001) in patients with LV. Although the frequency of bothosteopenia and osteoporosis were higher in patients with LV, the difference reached statistical significanceonly for osteoporosis (p = 0.007).Conclusions: Women with LV have lower BMD values and higher osteoporosis rates than age- and BMImatchedcontrols; therefore, osteoporosis should be evaluated in these patients.

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