MORINGA OLEIFERA’NIN ETKİNLİK VE GÜVENLİĞİ
Amaç: Moringa oleifera Lamarck, Orta Doğu, Afrika ve Asya Ülkeleri’nde yetişen bir bitki olup; bu ülkelerde özellikle bitkinin tohumları ve yaprakları gıda olarak tüketilmektedir.
SAFETY AND EFFICACY OF MORINGA OLEIFERA
Objective: Moringa oleifera Lamarck is a plant grown in Middle East, Africa and Asian countries, where seeds and leaves of the plant are consumed as food in these countries.
___
- 1. Ghazali, Hasanah Mohd, & Mohammed, Abdulkarim Sabo. (2011). Moringa (Moringa oleifera) Seed Oil. In Nuts and Seeds in Health and Disease Prevention (pp. 787-793).
- 2. Abd Rani, N. Z., Husain, K., & Kumolosasi, E. (2018). Moringa Genus: A Review of Phytochemistry and Pharmacology. Front Pharmacol, 9, 108. [CrossRef]
- 3. The Plant List Web site. (2021), http://www.theplantlist.org/tpl1.1/search?q=moringa, Erişim tarihi: 21 Mart 2021.
- 4. Saa, Romuald Willy, Fombang, Edith Nig, Ndjantou, Elie Baudelaire, & Njintang, Nicolas Yanou. (2019). Treatments and uses of Moringa oleifera seeds in human nutrition: A review. Food science & nutrition, 7(6), 1911-1919.
- 5. Mahfuz, S., & Piao, X. S. (2019). Application of Moringa (Moringa oleifera) as Natural Feed Supplement in Poultry Diets. Animals (Basel), 9(7). [CrossRef]
- 6. Parrotta, J. A. (1993). Moringa Oleifera Lam: Resedá, Horseradish Tree, Moringaceae, Horseradish-tree Family. International Institute of Tropical Forestry. US Department of Agriculture, Forest Service.
- 7. Leone, A., Spada, A., Battezzati, A., Schiraldi, A., Aristil, J., & Bertoli, S. (2015). Cultivation, Genetic, Ethnopharmacology, Phytochemistry and Pharmacology of Moringa oleifera Leaves: An Overview. Int J Mol Sci, 16(6), 12791-12835. [CrossRef]
- 8. Richter, Nahid, Siddhuraju, Perumal, & Becker, Klaus. (2003). Evaluation of nutritional quality of moringa (Moringa oleifera Lam.) leaves as an alternative protein source for Nile tilapia (Oreochromis niloticus L.). Aquaculture, 217(1-4), 599-611. [CrossRef]
- 9. Leone, A., Spada, A., Battezzati, A., Schiraldi, A., Aristil, J., & Bertoli, S. (2016). Moringa oleifera Seeds and Oil: Characteristics and Uses for Human Health. Int J Mol Sci, 17(12). [CrossRef]
- 10. Kayode, R. M., & Afolayan, A. J. (2015). Cytotoxicity and effect of extraction methods on the chemical composition of essential oils of Moringa oleifera seeds. J Zhejiang Univ Sci B, 16(8), 680-689. [CrossRef]
- 11. Gharsallah, Karima, Rezig, Leila, Msaada, Kamel, Chalh, Abdellah, & Soltani, Taoufik. (2021). Chemical composition and profile characterization of moringa oleifera seed oil. South African Journal of Botany, 137, 475-482. [CrossRef]
- 12. Zhao, Beibei, Li, Hua, Lan, Tao, Wu, Di, & Chen, Zhicheng. (2019). Characterization of the Chemical Composition of Chinese Moringa oleifera Seed Oil. Journal of the American Oil Chemists' Society, 96(5), 523-533. [CrossRef]
- 13. Mbah, B. O., Eme, P. E., & Ogbusu, O. F. (2012). Effect of cooking methods (boiling and roasting) on nutrients and anti-nutrients content of Moringa oleifera seeds. Pakistan Journal of Nutrition, 11(3), 211. [CrossRef]
- 14. Tsaknis, J., Lalas, S., Gergis, V., Dourtoglou, V., & Spiliotis, V. (1999). Characterization of Moringa oleifera variety Mbololo seed oil of Kenya. Journal of Agricultural and food chemistry, 47(11), 4495-4499. [CrossRef]
- 15. Brunelli, D., Tavecchio, M., Falcioni, C., Frapolli, R., Erba, E., Iori, R., . . . D'Incalci, M. (2010). The isothiocyanate produced from glucomoringin inhibits NF-kB and reduces myeloma growth in nude mice in vivo. Biochem Pharmacol, 79(8), 1141-1148. [CrossRef]
- 16. Singh, R. G., Negi, P. S., & Radha, C. (2013). Phenolic composition, antioxidant and antimicrobial activities of free and bound phenolic extracts of Moringa oleifera seed flour. Journal of functional foods, 5(4), 1883-1891.
- 17. Teixeira, E. M., Carvalho, M. R., Neves, V. A., Silva, M. A., & Arantes-Pereira, L. (2014). Chemical characteristics and fractionation of proteins from Moringa oleifera Lam. leaves. Food Chem, 147, 51-54. [CrossRef]
- 18. Özcan, M. M., Ghafoor, K., Al Juhaimi, F., Ahmed, I. A. M., & Babiker, E. E. (2019). Effect of cold-press and soxhlet extraction on fatty acids, tocopherols and sterol contents of the Moringa seed oils. South African Journal of Botany, 124, 333-337. [CrossRef]
- 19. Koike, M. K., Kochi, A. K., & Pinto, D. Y. G. (2020). Use of Moringa Oleifera Seeds in Water Treatment. Arq Bras Cardiol, 114(6), 1038-1039. [CrossRef]
- 20. Gopalakrishnan, Lakshmipriya, Doriya, Kruthi, & Kumar, Devarai Santhosh. (2016). Moringa oleifera: A review on nutritive importance and its medicinal application. Food Science and Human Wellness, 5(2), 49-56. [CrossRef]
- 21. Kou, X., Li, B., Olayanju, J. B., Drake, J. M., & Chen, N. (2018). Nutraceutical or Pharmacological Potential of Moringa oleifera Lam. Nutrients, 10(3). [CrossRef]
22. Dhakad, A. K., Ikram, M., Sharma, S., Khan, S., Pandey, V. V., & Singh, A. (2019). Biological, nutritional, and therapeutic significance of Moringa oleifera Lam. Phytother Res, 33(11), 2870-2903. [CrossRef]
- 23. Jacques, A. S., Arnaud, S. S., Fr&ejus, O. O., & Jacques, D. T. . (2020). Review on biological and immunomodulatory properties of Moringa oleifera in animal and human nutrition. . Journal of Pharmacognosy and Phytotherapy, 12(1), 1-9. [CrossRef]
- 24. Li, Y. J., Ji, Q. Q., Wang, Z., Shen, L. H., & He, B. (2020). Moringa oleifera seeds mitigate myocardial injury and prevent ventricular failure induced by myocardial infarction. Am J Transl Res, 12(8), 4511-4521.
- 25. Fatoumata, B. A., MamadouSaïdou, B. A. H., Mohamet, Sene, Joseph, Koulanzo Sambou, Modou, Mbacké Gueye, & El, HadjiMakhtar B. A. (2020). Antidiabetic properties of Moringa oleifera: A review of the literature. Journal of Diabetes and Endocrinology, 11(1), 18-29. [CrossRef]
- 26. Gupta, R., Mathur, M., Bajaj, V. K., Katariya, P., Yadav, S., Kamal, R., & Gupta, R. S. (2012). Evaluation of antidiabetic and antioxidant activity of Moringa oleifera in experimental diabetes. J Diabetes, 4(2), 164-171. [CrossRef]
- 27. Ma, Z. F., Ahmad, J., Zhang, H., Khan, I., & Muhammad, S. (2020). Evaluation of phytochemical and medicinal properties of Moringa (Moringa oleifera) as a potential functional food. South African Journal of Botany, 129, 40-46. [CrossRef]
- 28. Villarruel-Lopez, A., Lopez-de la Mora, D. A., Vazquez-Paulino, O. D., Puebla-Mora, A. G., Torres-Vitela, M. R., Guerrero-Quiroz, L. A., & Nuno, K. (2018). Effect of Moringa oleifera consumption on diabetic rats. BMC Complement Altern Med, 18(1), 127. [CrossRef]
- 29. Vargas-Sanchez, K., Garay-Jaramillo, E., & Gonzalez-Reyes, R. E. (2019). Effects of Moringa oleifera on Glycaemia and Insulin Levels: A Review of Animal and Human Studies. Nutrients, 11(12). [CrossRef]
- 30. Haber, S. L., McMahon, R. P., Barajas, J., Hayes, A. R., & Hussein, H. (2020). Effects of Moringa oleifera in patients with type 2 diabetes. Am J Health Syst Pharm, 77(22), 1834-1837. [CrossRef]
- 31. Suphachai, Charoensin. (2014). Antioxidant and anticancer activities of Moringa oleifera leaves. Journal of Medicinal Plants Research, 8(7), 318-325. [CrossRef]
- 32. Islam, Z., Islam, S. M. R., Hossen, F., Mahtab-Ul-Islam, K., Hasan, M. R., & Karim, R. (2021). Moringa oleifera is a Prominent Source of Nutrients with Potential Health Benefits. Int J Food Sci, 2021, 6627265. [CrossRef]
- 33. Wisitpongpun, P., Suphrom, N., Potup, P., Nuengchamnong, N., Calder, P. C., & Usuwanthim, K. (2020). In Vitro Bioassay-Guided Identification of Anticancer Properties from Moringa oleifera Lam. Leaf against the MDA-MB-231 Cell Line. Pharmaceuticals (Basel), 13(12). [CrossRef]
- 34. Karim, N. A. A., Ibrahim, M. D., Kntayya, S. B., Rukayadi, Y., Hamid, H. A., & Razis, A. F. A. (2016). Moringa oleifera Lam targeting chemoprevention. Asian Pacific Journal of Cancer Prevention, 17(8), 3675-3686.
- 35. Varalakshmi, K. N., & Nair, Shruti. (2011). Anticancer, cytotoxic potential of Moringa oleifera extracts on HeLa cell line. Journal of Natural Pharmaceuticals, 2(3). [CrossRef]
36. Al-Asmari, A. K., Albalawi, S. M., Athar, M. T., Khan, A. Q., Al-Shahrani, H., & Islam, M. (2015). Moringa oleifera as an anti-cancer agent against breast and colorectal cancer cell lines. PloS one, 10(8), e0135814. [CrossRef]
- 37. Szlachetka, Kinga, Kut, Paulina, & Stępień, Agnieszka. (2020). Cytotoxic and anticancer activity of Moringa oleifera. European Journal of Clinical and Experimental Medicine, 18(3), 214-220. [CrossRef]
- 38. Saleem, Ammara, Saleem, Mohammad, & Akhtar, Muhammad Furqan. (2020). Antioxidant, anti-inflammatory and antiarthritic potential of Moringa oleifera Lam: An ethnomedicinal plant of Moringaceae family. South African Journal of Botany, 128, 246-256. [CrossRef]
- 39. Mansour, M., Sherif, M., Ismail, Y., Abd Elhameed, A., & Awad, S. (2021). Study of The Possible Effect of Fluoxetine, Moringa Oleifera and Methotrexate in A Rat Model Of Rheumatoid Arthritis. Benha Medical Journal. [CrossRef]
- 40. V. Balamurugan*, L . Muruganandam. (2021). IN-VITRO ANTI-INFLAMMATORY AND ANTI-ARTHRITIC ACTIVITY OF CARDIOSPERMUM HALICACABUM AND MORINGA OLEIFERA LEAVES EXTRACT. Journal of Advanced Scientific Research.
- 41. Kumar, V., Verma, A., Ahmed, D., Sachan, N. K., Anwar, F., & Mujeeb, M. (2013). Fostered antiarthritic upshot of moringa oleifera lam. stem bark extract in diversely induced arthritis in wistar rats with plausible mechanism. International journal of pharmaceutical sciences and research, 4(10), 3894-01. [CrossRef]
- 42. Wang, F., Bao, Y., Zhang, C., Zhan, L., Khan, W., Siddiqua, S., . . . Xiao, J. (2021). Bioactive components and anti-diabetic properties of Moringa oleifera Lam. Crit Rev Food Sci Nutr, 1-25.
- 43. Anwar, F., & Rashid, U. (2007). Physico-chemical characteristics of Moringa oleifera seeds and seed oil from a wild provenance of Pakistan. Pak. J. Bot, 39(5), 1443-1453.
- 44. Oyeyinka, Adewumi T., & Oyeyinka, Samson A. (2018). Moringa oleifera as a food fortificant: Recent trends and prospects. Journal of the Saudi Society of Agricultural Sciences, 17(2), 127-136. [CrossRef]
- 45. Lin, Mengfei, Zhang, Junjie, & Chen, Xiaoyang. (2018). Bioactive flavonoids in Moringa oleifera and their health-promoting properties. Journal of Functional Foods, 47, 469-479. [CrossRef]
- 46. Kumar, G., Giri, A., Arya, R., Tyagi, R., Mishra, S., Mishra, A. K., & Datta, J. . (2019). Multifaceted applications of different parts of Moringa species: Review of present status and future potentials. International Journal of Chemical Studies, 7(2), 835-842.