Kantaron (Hypericum perforatum L.) bitkisinin eski çağlardan günümüze kullanım şekilleri ile modern tıptaki yeri ve önemi

Kantaron (Hypericum perforatum L.) ülkemizde tarla, yol ve orman kıyılarında doğal olarak bulunan ve binbirdelik otu, kan otu, kılıç otu gibi yöresel adlara sahip çok yıllık otsu bir tıbbi bitkidir. Bitki, naphthodianthronlar ve xanthonlar başta olmak üzere en az on farklı sınıfa dahil biyolojik aktif sekonder metabolit ihtiva etmektedir. Bitkinin sergilediği çok yönlü farmakolojik etkiler yapılan birçok klinik çalışmayla ortaya konmuş olup son yıllarda bilhassa antidepresant olarak kullanımı yaygınlaşmıştır. Günümüzde kantarondan hazırlanan farklı formlardaki farmakolojik ürünlerin satış değeri dünya genelinde her yıl milyonlarca dolara ulaşmaktadır. Ülkemiz Hypericum türleri bakımından önemli bir merkezdir ve mevcut türlerin çoğu endemiktir. Dolayısıyla kantaron ülkemiz için değerlendirilmesi gereken doğal bir zenginliktir.

Anahtar Kelimeler:

Hypericum perforatum, biyoloji, tarih, tıbbi bitkiler, farmakoloji, bitki bileşimi, genel bakış, kullanım yerleri

Using forms from old ages to present time and position and importance of st. John's worth (Hypericum perforatum L.) in modern medicine

St. John's worth living in border of field, road and forest naturally and having local nouns such as binbirdelik otu, kan otu and kılıç otu is perennial and herbaceous medicinal plant. The plant contains namely naphthodianthrons and xanthons, biologically active secondary metabolites belonging to at least ten different classes. Pharmacological activities St. John's worth exhibits are demonstrated by a number of clinical studies and its using, especially as an antidepressant, has increased in recent years. Today, selling values of different forms of pharmacological products prepared St. John's worth has reached millions dollar every years in the world. Our country is an important gene resources centre for Hypericum species and lots of them are endemic. Consequently, St. John's worth is an natural resource to be evaluated for our country.

Keywords:

Hypericum perforatum, biology, history, medicinal plants, pharmacology, plant composition, reviews, uses,

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