Sığırlarda lökosit artışı ile seyreden hastalıklarda, lökosit artışı ile lipit peroksidasyonu arasındaki ilişkinin araştırılması

Bu çalışma, lökosit artışının saptandığı hasta hayvanlarda, lökosit artışı ile lipit peroksidasyonu arasında ne tür bir ilişki olduğunu araştırmak üzere planlandı. Lökosit artışı saptanan 20 hasta ve 20 sağlıklı olmak üzere toplam 40 hayvan çalışmanın deney hayvan materyalini oluşturdu. Bu hayvanlardan alınan kan örneklerinden malondialdehit MDA ve indirgenmiş glutatyon GSH analizleri hemen yapıldı. Malondialdehit değerleri hasta hayvanlarda sağlıklı hayvanlara oranla oldukça yüksek bulunurken, aradaki farkın istatistiksel anlamda önemli olduğu saptandı P

Anahtar Kelimeler:

Lökositozis, granulosit, malondialdehit, glutatyon, sığır

Investigation of the relationship between increased leukocyte levels and blood lipid peroxidation in the sick cattle with leukocytosis

This study was designed to investigate whether there was a relationship between increased leukocyte levels and blood lipid peroxidation in cows with leukocytosis. Elevation or/and activation of leukocytes cause an increase in the production of free radicals leading to the lipid peroxidation. Malondialdehide MDA is the most important marker for lipid peroxidation. Forty cows were investigated. Twenty animals diagnosed with leukocytosis were chosen to represent sick group. Twenty healthy animals were chosen as Controls. Blood samples were drown to measure MDA and glutathione levels. It was found that MDA level was signifıcantly higher P

Keywords:

Leucosytosis, granulocits, malondialdehide, glutathione, cattle,

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