Fenolik Bileşenler ve Bağırsak Bakterileri Arasında Karşılıklı Etkileşim

Bağırsak bakteri popülasyonunu anaerobik bakteriler olan Clostridium, Bifidobacterium, Peptococcus, Eubacterium, Fusobacterium, Peptostreptococcus, Bacteroides, E. coli, Lactobacillus, Klebsiella, Staphylococcus, Streptococcus ve Bacillus türleri oluşturmaktadır. Bu popülasyonu oluşturan bakterilerin insan sağlığını etkilediği bilinmektedir. Bu nedenle popülasyondaki herhangi bir değişiklik çeşitli hastalıklara (obezite, diyabet, hipertansiyon vb.) sebep olmaktadır. Bozulan bu dengeyi eski haline getirmek ve hastalıklardan korunmak için prebiyotiklere ihtiyaç duyulur. Meyve ve sebze gibi doğal gıdalardan oluşturulmuş bir diyet bağırsak mikrobiyotasının düzenlenmesinde önemli bir rol üstlenmektedir. Kızılcık, kuşburnu, kaki, domates, havuç, soya fasulyesi, ceviz, greyfurt gibi fenolik bileşenlerce zengin pek çok meyve-sebze bu anlamda önemlidir. Bu derlemenin amacı; fenolik bileşikler, genel mikrobiyota ve bağırsak mikrobiyotası hakkında bilgiler vermek ve bağırsak mikrobiyotasının fenolik bileşiklere, fenolik bileşiklerin de bağırsak mikrobiyotasına etkisini açıklamaktır.

Mutual Interaction Between Phenolic Compounds and Intestinal Bacteria

The intestinal bacterial populations constitute the anaerobic bacteria Clostridium, Bifidobacterium, Peptococcus, Eubacterium, Fusobacterium, Peptostreptococcus, Bacteroides, E. coli, Lactobacillus, Klebsiella, Staphylococcus, Streptococcus and Bacillus species. It is known that the bacteria that make up this population are affecting human health. Therefore, any change in the population causes various diseases (obesity, diabetes, hypertension etc.). Prebiotics are needed to restore this disrupted balance and to protect it from diseases. A diet made from natural foods such as fruit and vegetables plays an important role in the regulation of intestinal microbiota. Many fruit and vegetables rich in phenolic components such as corn, rosehip, trabzon, tomato, carrot, soybean, walnut, grapefruit are important in this sense. The purpose of this compilation is; phenolic compounds, general microbiota and intestinal microbiota and explain the effect of intestinal microbiota on phenolic compounds and phenolic compounds on intestinal microbiota.

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