Erhan Renan UÇAROĞLU, Erol ŞENER, Levent ÇETİN, Ayşegül KUNT, Mete HIDIROĞLU, Aslıhan KÜÇÜKER

İki gebe hastada gelişen mekanik kalp kapağı trombozunun düşük molekül ağırlıklı heparin tedavisi ile takibi: Olgu sunumu

Mekanik kalp kapağı olan hastalarda tromboembolik olayları önlemek için, ömür boyu antikoagülan tedavi zorunludur. Ancak mekanik kalp kapağı olan gebe hastaların tedavisinde hangi antikoagülan tedavi protokolünün en iyi olduğu hala tartışmalıdır. Bu yazıda, gebelik döneminde düşük molekül ağırlıklı heparin (DMAH) ile takip edilen ve mekanik kapaklarda tromboz gelişen iki gebe hasta sunuldu. Gebelik döneminde fetal yan etkilerden korunmak amacıyla oral antikoagülanlar kesilerek DMAH tedavisine geçirilen bu hastalar, gebelik dönemlerinin 10. haftası ve altıncı ayında gelişen mekanik kalp kapak trombozu nedeniyle acil olarak ameliyata alındı. Fetüs ve bebek kaybı gelişmesine rağmen, hastalar ameliyat sonrası dönemde iyileşti ve şifa ile taburcu edildi.

Mechanical heart valve thrombosis in two pregnant patients followed up with low-molecular weight heparin therapy: A case report

Life-long anticoagulation therapy is mandatory for patients with mechanical heart valves in order to prevent thromboembolic events. However, controversy still exists concerning which anticoagulant therapy protocol is best for pregnant patients with mechanical heart valves. In this article, we present two pregnant cases of mechanical heart valve thrombosis who were followed up with low-molecular weight heparin (LMWH) therapy. The patients, who were switched from anticoagulants to LMWH to prevent fetal side effects during pregnancy, underwent emergency surgery due to mechanical heart valve thrombosis in the 10th w eek a nd s ixth m onth o f pregnancy, respectively. Although fetal and baby loss occurred, the patients recovered in the postoperative period and were discharged uneventfully.

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