Ejder KARDEŞOĞLU, Mustafa Arpacı, Ömer UZ, Namık ÖZMEN, Bekir Sıtkı CEBECİ, Turgay ÇELİK, Atilla İYİSOY

Kronik sigara içiminin aortik elastikiyet üzerine etkisi

AMAÇ: Çalışmadaki amacımız, kronik sigara içiminin aortik elastikiyet üzerine etkilerini incelemektir. YÖNTEM: Çalışmaya kronik sigara kullanıcısı, tamamen sağlıklı ve orta düzeyde aktif olan 20 erkek birey (21,8±1,4 yıl) alındı (Sigara İçenler Grubu). Sigara içenler grubu; en az 3 yıl süre ile günde 10 adetten fazla sigara içmekte olan bireylerden oluşturulmuştur. Kontrol grubu ise tamamen sağlıklı, orta düzeyde aktif ve yaş ortalaması 21,6±1,5 yıl olan 25 erkek bireyden oluşturulmuştur. Öncelikle bireylerin nabız, sistolik kan basıncı (SKB) ve diyastolik kan basıncı (DKB) ölçülerek kayıt edildi. Ekokardiyografi ile modifiye parasternal uzun eksen görüntüden asendan aortanın M mod kayıtları alınarak aortun sistolik ve diyastolik çapları ölçüldü. Yapılan ölçümlerden Aortik elastikiyetin belirteçleri olan aortik strain (AS), aortik distensibilite (AD) ve beta sertlik indeksi (BSİ) standart formüller ile hesaplandı. Her iki grubun ölçülen ve hesaplanan parametreleri karşılaştırıldı. BULGULAR: Sigara içenler grubunda, sigara içme süresi 5,5±1,9 yıl ve sigara miktarı 16,2±3,8 adet/gün olarak belirlendi. İki grup arasında nabız, SKB, DKB, ejeksiyon fraksiyonu bakımından anlamlı fark tespit edilmedi. Ancak aortik strain ve aortik distensibilite Sigara İçenler Grubunda kontrol grubuna göre istatistiki olarak anlamlı derecede düşük, beta sertlik indeksi anlamlı derecede yüksek bulundu. SONUÇ: Sonuç olarak kronik sigara içen sağlıklı genç bireylerde aortik elastikiyet anlamlı derecede azalmış olduğu çalışmamızda gösterilmiştir.

Anahtar Kelimeler:

Tanı teknik ve işlemleri, Aort, Kan basıncı, Elastikiyet, Sigara içme

Effect of chronic smoking on aortic elasticity

AIM/BACKGROUND: In this study, we aimed to determine the effects of chronic smoking on aortic elasticity in healthy young individuals. METHODS: The study population was composed of healthy and moderately active 20 volunteer males (21.8±1.4 years old) who have smoked more than 10 cigarettes/day for at least 3 years and moderately active (Smoker Group). Twenty five healthy males were enrolled to the study as the control group (21.6 ±1.5 years old). Heart rate, systolic and diastolic blood pressures (SBP, DBP) of each subject were measured. Systolic and diastolic diameters of aorta were measured from ascending aorta at modified parasternal long axis views by M mode echocardiography. Parameters of aortic elasticity such as aortic strain (AS), aortic distensibility (AD) and stiffness index beta (SIB) were calculated using standart formulas. The parameters of groups were compared to each other. RESULTS: In the smoker group the mean duration of smoking and number of cigarettes were 5.5±1.9 years and 16.2±3.8 cigarettes per day, respectively. We did not find any statistical difference between groups in terms of ejection fraction, heart rate, SBP, and DBP. Aortic Strain and Aortic Distensibility were lower whereas stiffness index beta was higher in smoker group comparison to control group. CONCLUSION: In the conclusion, aortic elasticity was significantly decreased in chronically smoking healthy youths.

Keywords:

Diagnostic Techniques and Procedures, Aorta, Blood Pressure, Elasticity, Smoking,

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