Ahmet ÇAY, E. Perrin AKÇAKOCA KUMBASAR, Çiğdem AKDUMAN

ÇÖZGEN KARIŞIMLARININ ELEKTROLİF ÇEKİM YÖNTEMİ İLE ÜRETİLMİŞ TERMOPLASTİK POLİÜRETAN NANOLİFLERİNİN MORFOLOJİSİNE ETKİSİ

Termoplastik poliüretan (TPU) çözeltilerinin elektrolif çekim yöntemine göre çekilebilirliklerine ve elde edilen termoplastik poliüretan nanoliflerinin morfolojik görünümlerine çözgen karışımlarının etkileri taramalı electron mikroskopu (SEM) ile nitel olarak incelenmiştir. Çözgen olarak N,N-dimetilformamid (DMF), tetrahidrofuran (THF) ve etilasetat (EA) kullanılmıştır. TPU-DMF/THF ve TPU-DMF/EA çözeltileri ve elde edilen nanolifler, TPU-DMF sistemi ile elde edilen nanolifler ile karşılaştırılmıştır. Lif çapları artan THF hacim oranı ile artmıştır. 50/50 ve 40/60 DMF/THF karışımlarında lifler birbirlerie yapışmıştır ve elektrolif çekimi THF’nin düşük iletkenliği ve kaynama noktası ve hazırlanan çözeltilerin yüksek viskozitelerine bağlı olarak zorlaşmıştır. Diğer taraftan, 90/10 ve 80/20 DMF/EA ile hazırlanan çözeltilerden daha ince lif çapı olan nanolifler elde edilmiştir. Bu nedenle TPU çözeltilerini %10 veya %20 EA ile seyreltmek elektrolif çekim yöntemine gore elde edilen nanolifler üzerine olumlu etki yapmaktadır

Anahtar Kelimeler:

Termoplastik poliüretan, elektrolif çekimi, nanolifler, çözgenler

EFFECTS OF SOLVENT MIXTURES ON THE MORPHOLOGY OF ELECTROSPUN THERMOPLASTIC POLYURETHANE NANOFIBRES

The effects of solvent mixtures on the electro-spinnability of the thermoplastic polyurethane (TPU) solutions and the morphological appearance of the electrospun thermoplastic polyurethane nanofibres were investigated qualitatively by means of a scanning electron microscope (SEM). N,N-dimethylformamide (DMF), tetrahydrofuran (THF) and ethylacetate (EA) were used as solvents. TPUDMF/THF and TPU-DMF/EA solutions and the resultant nanofibres were compared to those produced by TPU-DMF system. Fibre diameters increased with the increasing THF volume fraction. At 50/50 and 40/60 DMF/THF mixtures fibres were fused to adjacent fibres and electrospinning is restricted due to low conductivity and low boiling point of the THF, and the high viscosity of the prepared solution. On the other hand, 90/10 and 80/20 DMF/EA solutions led to lower nanofibre diameters. Therefore, diluting TPU solutions with 10 or 20 % of EA had positive effect on electrospun nanofibres

Keywords:

Thermoplastic polyurethane, electrospinning, nanofibres, solvents,

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1- Gopa, R., Kaur, S., Maa, Z., Chanc, C., Ramakrishna, S., Matsuura, T., 2006, “Electrospun nanofibrous filtration membrane”, Journal of Membrane Science, 281, 581-586.
2- Qin, X., Wang, S., 2006, “Filtration properties of electrospinning nanofibers”, Journal of Applied Polymer Science, 102, 1285-1290.
3- Yun, K.M., Hogan Jr., C.J., Matsubayashi, Y., Kawabe, M., Iskandar, F., Okuyama, K., 2007, “Nanoparticle filtration by electrospun polymer fibers”, Chemical Engineering Science, 62, 4751-4759.
4- Uyar, T., Havelund, R., Nur, Y., Hacaloglu, J., Besenbacher, F., Kingshott, P., 2009, “Molecular filters based on cyclodextrin functionalized electrospun fibers”, Journal of Membrane Science, 332, 129-137.
5- Chunder, A., Sarkar, S., Yu, Y., Zhai, L., 2007, “Fabrication of ultrathin polyelectrolyte fibers and their controlled release properties”, Colloids and Surfaces B: Biointerfaces, 58, 172-179.
6- Dotti, F., Varesano, A., Montarsolo, A., Aluigi, A., Tonin, C., Mazzuchetti, G., 2007, “Electrospun porous mats for high efficiency filtration”, Journal of Industrial Textiles, 37, 151-162.
7- Qin, X., Wang, S., 2008, “Electrospun nanofibers from crosslinked poly(vinyl alcohol) and its filtration efficiency”, Journal of Applied Polymer Science, 109, 951-956.
8- Sill, T.J., von Recum, H.A., 2008, “Electrospinning: Applications in drug delivery and tissue engineering”, Biomaterials, 29, 1989-2006.
9- Menga, Z.X., Zhenga, W., Lia, L. , Zheng, Y.F., 2011, “Fabrication, characterization and in vitro drug release behavior of electrospun PLGA/chitosan nanofibrous scaffold”, Materials Chemistry and Physics, 125, 606-611.
10- Liang, D., Hsiao, B.S., Chu, B., 2007, “Functional electrospun nanofibrous scaffolds for biomedical applications”, Advanced Drug Delivery Reviews, 59, 1392-1412.
11- Verreck, G., Chun, I., Rosenblatt, J., Peeters, J., Dijck A.V., Mensch, J., Noppe, M., Brewster, M.E., 2003, “Incorporation of drugs in an amorphous state into electrospun nanofibers composed of a water-insoluble, nonbiodegradable polymer”, Journal of Controlled Release, 92, 349- 360.
12- Kim, K., Luu, Y.K., Chang, C., Fang, D., Hsiao, B.S., Chu, B., Hadjiargyrou, M., 2004, “Incorporation and controlled release of a hydrophilic antibiotic using poly(lactide-co-glycolide)-based electrospun nanofibrous scaffolds”, Journal of Controlled Release, 98, 47- 56.
13- Kenawy, E., Bowlin, G.L., Mansfield, K., Layman, J., Simpson, D. G., Sanders, E. H., Wnek, G. E., 2002, “Release of tetracycline hydrochloride from electrospun poly(ethylene-co-vinylacetate), poly(lactic acid), and a blend”, Journal of Controlled Release, 81, 57-64.
14- Kenawy, E., Abdel-Haya, F.I., El-Newehya, M.H., Wnekb, G.E., 2009, “Processing of polymer nanofibers through electrospinning as drug delivery systems”, Materials Chemistry and Physics, 113, 296-302.
15- Zeng, J., Xu, X., Chen, X., Liang, Q., Bian, X., Yang, L., Jing, X., 2003, “Biodegradable electrospun fibers for drug delivery”, Journal of Controlled Release, 92, 227-231.
16- Xu, X., Zhong, W., Zhou, S., Trajtman, A., Alfa, M., 2010, “Electrospun PEG–PLA nanofibrous membrane for sustained release of hydrophilic antibiotics”, Journal of Applied Polymer Science, 118, 588-595.
17- Zong, X., Ran, S., Kim, K., Fang, D., Hsiao, B.S., Chu, B., 2003, “Structure and morphology changes during in vitro degradation of electrospun poly(glycolide-co-lactide) nanofiber membrane”, Biomacromolecules, 4, 416-423.
18- Zeng, J., Yang, L., Liang, Q., Zhang, X., Guan, H., Xu, X., Chen, X., Jing, X., 2005, “Influence of the drug compatibility with polymer solution on the release kinetics of electrospun fiber formulation”, Journal of Controlled Release, 105, 43-51. 19- Teo, W.E., Ramakrishna, S., 2006, “A review on electrospinning design and nanofibre assemblies”, Nanotechnology, 17, 89-106.
20- Ramakrishna, S., Fujihara, K., Teo, W., Lim, T., Ma, Z., 2005, An introduction to electrospinning and nanofibers, World Scientific Publishing Co. Pte. Ltd., Singapore.
21- Wannatong, L., Sirivat, A., Supaphol, P., 2004, “Effects of solvents on electrospun polymeric fibers: preliminary study on polystyrene”, Polymer International, 53, 1851-1859.
22- Son, W.K, Youk, J.H, Lee, T.S. Park, W.H., 2004, “The effects of solution properties and polyelectrolyte on electrospinning of ultrafine poly(ethylene oxide) fibers”, Polymer, 45, 2959-2966.
23- Lee, K.H., Kim, H.Y., Ra, Y.M., Lee, D.R., 2003, “Characterization of nanostructured poly(e-caprolactone) nonwoven mats via electrospinning”, Polymer, 44, 1287-1294.
24- Hsu, C.M., Shivakumar, S., 2004, “N,N-dimethylformamide additions to the solution for the electrospinning of poly(e-caprolactone) nanofibers”, Macromolecular Materials Engineering, 289, 334-340.
25- Jarusuwannapoom, T., Hongrojjanawiwat, W., Jitjaicham, S., Wannatong, L., Nithitanakul, M., Pattamaprom, C., Koombhongse, P., Rangkupan, R., Supaphol, P., 2005, “Effect of solvents on electro-spinnability of polystyrene solutions and morphological appearance of resulting electrospun polystyrene fibers”, European Polymer Journal, 41, 409-421.
26- Theron, S.A., Zussman, E., Yarin, A.L., 2004, “Experimental investigation of the governing parameters in the electrospinning of polymer solutions”, Polymer, 45, 2017-2030.
27- Megelski, S., Stephens, J.S., Chase, D.,B., Rabolt, J.F., 2002, “Micro- and nanostructured surface morphology on electrospun polymer fibers”, Macromolecules, 35, 8456-8466.
28- Song, J., Kim, H.E., Kim, H.W., 2008, “Production of electrospun gelatin nanofiber by water-based co-solvent approach”, Journal of Materials Science: Materials in Medicine, 19, 95-102.
29- Tungprapa, S., Puangparn, T., Weerasombut, M., Jangchud, I., Fakum, P., Semongkhol, S., Meechaisu, C., Supaphol, P., 2007, “Electrospun cellulose acetate fibers: effect of solvent system on morphology and fiber diameter”, Cellulose, 14, 563-575.
30- Huynh, T.T.N.Y, Padois, K., Sonvico, F., Rossi, A., Zani, F., Pirot, F., Doury, J., Falson, F., 2010, “Characterization of a polyurethane-based controlled release system for local delivery of chlorhexidine diacetate”, European Journal of Pharmaceutics and Biopharmaceutics, 74, 255-264.
31- http://www.snsnano.com/products.asp#prod, available on January 2015.
32- Akduman, Ç., Özgüney, I., Akçakoca Kumbasar, E. P., 2014, “Electrospun thermoplastic polyurethane mats containing naproxen-cyclodextrin inclusion complex, Autex Research Journal, 14(4), 239-246.
33- Yanılmaz, M., Kalaoğlu, F., Karakaş, H., 2012, “Study on optimising the morphology of electrospun polyurethane nanofibers”, Tekstil ve Konfeksiyon, 22(3), 212-217.
34- Dasdemir, M., Topalbekiroglu, M., Demir, A., 2013, “Electrospinning of thermoplastic polyurethane microfibers and nanofibers from polymer solution and melt, Journal of Applied Polymer Science, 127, 1901-1908.
35- Mi, H.-Y., Jing, X., Jacques, B.R., Turng, L.-S., Peng, X.-F., 2013, “Characterization and properties of electrospun thermoplastic polyurethane blend fibers: Effect of solution rheological properties on fiber formation”, Journal of Materials Research, 28(17), 2339-2350.
36- Yanilmaz, M., Kalaoglu, F., Karakas, H., 2013, “Investigation on the effect of process variables on polyurethane nanofibre diameter using a factorial design”, Fibres & Textiles in Eastern Europe, 21, 19-21.
37- http://www.rowak.ch/en/glossary/Polyurethane.php, available on September 2014.
38- Mondal, S., 2014, “Influence of solvents properties on morphology of electrospun polyurethane nanofiber mats”, Polymers Advanced Technologies, 25, 179-183.
39- http://www.sigmaaldrich.com/content/dam/sigma-aldrich/docs/Aldrich/General_Information/polymer_solutions.pdf, available on September 2014.
40- Akçakoca Kumbasar, E.P., Akduman, Ç., Çay, A., 2013, “Electrospinning parameters for thermoplastic polyurethane (TPU) nanofibers”, Proceedings of the 13th AUTEX World Textile Conference, Eds: Dörfel, A., Sankaran V., Dresden, Germany.
41- Wendorff, J.H., Agarwal, S., Greiner, A., 2012, “Nature of the Electrospinning Process – Experimental Observations and Theoretical Analysis” in Electrospinning, Materials, Processing, and Applications, Wiley-VCH Verlag & Co. KGaA, Weinheim, 36-52.
42- http://www.specialchem4adhesives.com/tds/pearlstick-45-50-29/merquinsa/15245/index.aspx, available on September 2014.
43- http://www.matweb.com/search/datasheettext.aspx?matguid=ea84676406bf4cc18951b8ec16f125f5, available on September 2014.
44- Mit-uppatham, C., Nithitanakul, M., Supaphol, P., 2004, “Ultrafine electrospun polyamide-6 fibers: effect of solution conditions on morphology and average fiber diameter”, Macromolecular Chemistry and Physics, 205, 2327-2338.