Üriner Sistem Enfeksiyonu Olan Çocuklarda İdiopatik Hiperkalsiüri Sıklığı
Amaç: Çalışmamızda idrar yolu enfeksiyonu olan hastalarda idrar ile kalsiyum atılımının rolünü değerlendirmeyiamaçladık. Yöntem ve Gereçler: İdrar yolu enfeksiyonu tanısı olan 100 çocuk ve sağlıklı 50 çocuk alındı. Çalışmaya alınantüm olguların sabah ikinci idrar örneklerinde, idrar kalsiyum / kreatinin oranı bakılarak 0,21 ve üzerinde değerlerhiperkalsiüri olarak kabul edildiBulgular : Kırıkkale Üniversitesi Tıp Fakültesi Çocuk Nefroloji polikliniğinde görülen idrar yolu enfeksiyonu olanhastalarda hiperkalsiüri birlikteliğini saptamak için yaptığımız çalışmamızda hiperkalsiüri prevalansını, çalışmagrubunda %9,9, kontrol grubunda %8 tespit ettik. Kontrol grubu ile çalışma grubu kıyaslandığında hiperkalsiürisıklığı yönünden fark bulundu Sonuç: İdrar yolu enfeksiyonu olan hastalarda üriner kalsiyum düzeyi bakılmalıdır
Idiopathic Hypercalciuria in Children With Urinary Tract Infection
Aim: We aimed to evaluate the role of urinary calcium excretion in children with urinary tract infections. Material And Methods: This study was performed on 100 children with urinary tract infections and 50 healthy cont- rols. Urinary calcium/creatinine ratio was examined in the second urine samples of all cases obtained in the morning,and any ratio above 0.21 was considered hypercalciuric.Result: In the present study conducted to detect hypercalciuria in the patients seen at the Pediatric Nephrology outpa- tient clinic of Kırıkkale University School of Medicine, prevalence of hypercalciuria was 9,9 % in the patient group,and 8%in the control group. When compared to the control group, prevalence of hypercalciuria was higher. Concluction : The investigation of urinary calcium excretion in children with urinary tract infections is recommended.
___
- 1. Balestracci A, Battaglia LM, Toledo I, Martin SM, Wainsztein RE. Idiopathic hypercalciuria in children with urinary tract infection. Arch Argent Pediatr. 2014;112:428-433.
- 2. Saadeh SA, Mattoo TK. Managing urinary tract infections. Pediatr Nephrol. 2011;26:1967-1976
- 3. Schwaderer A, Srivastava T. Complications of hypercalciuria. Front Biosci (Elite Ed). 2009 ;1:306-315.
- 4. Gordon I, Barkovics M, Pindoria S, Cole TJ, Woolf AS. Primary vesicoureteric reflux as a predictor of renal damage in children hospitalized with urinary tract infection: a systematic review and meta-analysis. J Am Soc Nephrol. 2003;14:739-744.
- 5. Stojanović VD, Milosević BO, Djapić MB, Bubalo JD. Idiopathic hypercalciuria associated with urinary tract infection in children Pediatr Nephrol. 2007;22:1291-1295
- 6. Mahmoodzadeh H, Nikibakhsh A, Karamyyar M, Gheibi S, Gholizadeh S, Hooshmand H. Idiopathic hypercalciuria in children with vesico ureteral reflux and recurrent urinary tract infection. Urol J. 2010;10:95-98.
- 7. Kuo RL, Lingeman JE, Evan AP, et al. Urine calcium and volume predict coverage of renal papilla by Randall's plaque. Kidney Int 2003;64:2150.
- 8. Nikibakhsh A A, Mahmoodzadeh H, Karamyyar M, Ghafari A, Yekta Z, Vafaie M Hypercalciuria Associated with Recurrent Urinary Tract Infections in. Children. Med J. Tabriz university of Med sci 2007; 29:23-26
- 9. Biyikli NK, Alpay H, Guran T. Hypercalciuria and recurrent urinary tract infections: incidence and symptoms in children over 5 years of age. Pediatr Nephrol. 2005 ;20:1435-1438
- 10. López M, Castillo LA, Juan B. Chávez and Carmen Ramones. Hypercalciuria and recurrent urinary tract infection in Venezuelan children. Pediatric Nephrol. 1999;13: 433-437
- 11. Garcia-Nieto V, Siverio B, Monge M, Toledo C, Molini N. Urinary calcium excretion in children with vesicoureteral reflux. Nephrol Dial Transplant. 2003;18:507-511.
- 12. Noe HN, Stapleton FB, Jerkins GR, Roy S, 3rd. Clinical experience with pediatric urolithiasis. J Urol. 1983;129:1166-1168
- 13. Çalışkan S, Ertan T Sever L, Arısoy N. İstanbulda çocuklarda hiperkalsiüri taraması. İstanbul Çocuk Klinik Dergisi 1992:24-36
- 14. Stephen W Leslie, Sahar Fathallah-Shaykh, Vecihi Batuman, Frederick J Kaske http://emedicine.medscape.com/article/2182757 - overview Updated:Aug 26,2013
- 15. Vachvanichsanong P, Malagon M, Moore ES. Recurrent abdominal and flank pain in children with idiopathic hypercalciuria. Acta Pediatr 2001;90: 643648.
- 16. Fallahzadeh MK, Fallahzadeh MH, Mowla A, Derakhshan A. Hypercalciuria in children with urinary tract symptoms. Saudi J Kidney Dis Transpl. 2010 ;21:673-677